{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T06:25:12Z","timestamp":1790922312568,"version":"4.1.0"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,7]]},"abstract":"\n Background:<\/jats:title>\n Dental caries is one of the most common chronic childhood diseases and is a cause of continuous discomfort through impaired function and esthetics. To control dental caries, the removal of plaque is of utmost importance, and that further necessitates the use of chemotherapeutic agents. Several side effects associated with chlorhexidine have stimulated the search for an alternative chemotherapeutic agent.<\/jats:p>\n <\/jats:sec>\n \n Aims:<\/jats:title>\n \n This study aims to compare the effectiveness of probiotic mouth rinse with kidodent mouth rinse, and placebo against mutans\n Streptococcus<\/jats:italic>\n and\n Lactobacillus acidophilus<\/jats:italic>\n (LA).\n <\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n The present study was a randomized parallel double-blinded clinical study which included 90 children of ages 6\u201315 years who were randomly allocated into three groups: Group 1 \u2013 placebo (\n n<\/jats:italic>\n = 30), Group 2 \u2013 kidodent (\n n<\/jats:italic>\n = 30), and Group 3 \u2013 probiotic (\n n<\/jats:italic>\n = 30). Stimulated salivary samples were collected from all the children after rinsing with distilled water (first reading), and after rinsing with respective mouthwash (placebo\/kidodent\/probiotic mouth rinse) of their groups during the first visit (second readings). Samples were collected again after using mouth rinse for 14 days (third readings) and used for detection of pH, and levels of\n Streptococcus mutans<\/jats:italic>\n (SM) and LA counts. Data were subjected to statistical analysis.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n Statistically significant difference was seen between placebo versus kidodent, placebo versus probiotic but there was no statistically significant difference between kidodent versus probiotic after the immediate rinse and post 15 days of rinse.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Kidodent and probiotic mouth rinse are more efficacious and have equivalent efficacy in reducing SM and LA.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/aam.aam_95_22","type":"journal-article","created":{"date-parts":[[2023,7,7]],"date-time":"2023-07-07T01:27:27Z","timestamp":1688693247000},"page":"365-372","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":8,"title":["Effectiveness of Three Mouth Rinsing Agents Against Mutans Streptococcus and Lactobacillus Species \u2013 A Comparative Study"],"prefix":"10.4103","volume":"22","author":[{"given":"Vijaya Lakshmi","family":"Bolla","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Jyothi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanthan Reddy","family":"Mettu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mallela G.","family":"Manoj Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kakumanu Nageswara","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Munnangi Surendra","family":"Reddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradeep","family":"Koppolu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20-20240831","doi-asserted-by":"crossref","first-page":"242","DOI":"10.4103\/jispcd.JISPCD_157_17","article-title":"Comparison between antibacterial effect of chlorhexidine 0.2% and different concentrations of Cyperus rotundus extract: An In vitro study","volume":"7","author":"Haghgoo","year":"2017","journal-title":"J Int Soc Prev Community Dent"},{"key":"R2-20-20240831","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/BF03262809","article-title":"A comparative evaluation of probiotics on salivary mutans streptococci counts in Indian children","volume":"12","author":"Jindal","year":"2011","journal-title":"Eur Arch Paediatr 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comparative evaluation of the efficacy of probiotic and chlorhexidine mouthrinses on clinical inflammatory parameters of gingivitis: A randomized controlled clinical study","volume":"19","author":"Nadkerny","year":"2015","journal-title":"J Indian Soc Periodontol"},{"key":"R10-20-20240831","doi-asserted-by":"crossref","first-page":"71","DOI":"10.4103\/2229-5194.126862","article-title":"Role of probiotics on oral health: A randomized, double-blind, placebo-controlled study","volume":"3","author":"Dhawan","year":"2013","journal-title":"J Interdiscip Dent"},{"key":"R11-20-20240831","doi-asserted-by":"crossref","first-page":"S86","DOI":"10.1097\/01.mcg.0000128925.06662.69","article-title":"Bacillus clausii probiotic strains: Antimicrobial and immunomodulatory activities","volume":"38","author":"Urdaci","year":"2004","journal-title":"J Clin Gastroenterol"},{"key":"R12-20-20240831","doi-asserted-by":"crossref","first-page":"179","DOI":"10.4103\/0970-4388.73799","article-title":"Efficacy of a probiotic and chlorhexidine mouth rinses: A short-term clinical study","volume":"28","author":"Harini","year":"2010","journal-title":"J Indian Soc Pedod Prev Dent"},{"key":"R13-20-20240831","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.archoralbio.2004.08.007","article-title":"Influence of sample type and collection method on Streptococcus mutans and Lactobacillus spp. Counts in the oral cavity","volume":"50","author":"Motisuki","year":"2005","journal-title":"Arch Oral Biol"},{"key":"R14-20-20240831","first-page":"1","article-title":"Effectiveness of different preventive proceduresin the control of cariogenic risk factors in children","volume":"55","author":"Juri","year":"2011","journal-title":"Paediatr Croat"},{"key":"R15-20-20240831","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/S2221-1691(11)60106-8","article-title":"Efficacy of xylitol and fluoride mouthrinses on salivary Mutans 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