{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T18:35:34Z","timestamp":1793212534613,"version":"4.5.0"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>This study was performed to investigate the effect of prescribing remifentanil, along with paracetamol and gabapentin in comparison of fentanyl and morphine, on pain relief and faster recovery of patients undergoing coronary artery bypass graft (CABG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Method:<\/jats:title>\n                    <jats:p>A double-blind controlled randomized clinical trial study was performed on 60 CABG candidates. In the control group, the patients underwent anesthesia drugs, analgesic drugs (fentanyl and morphine), and muscle relaxant drugs (without premedication with paracetamol, gabapentin, and remifentanil). In the intervention group, in addition to the control group medications, and bolus doses of remifentanil were used as an analgesic during the operation if analgesia was needed. Also, gabapentin 300 mg orally 1 h before surgery; gabapentin 300 mg every 8 h in the ICU; paracetamol 1 g as an intravenous infusion 30 min before the induction of anesthesia; Paracetamol 1 g every 6 h in the ICU for 3 days were prescribed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The pain scores mean in the intervention group on the first, second, and third days after CABG were significantly lower than the control group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05). Also, the percentage of delirium in the control group was significantly higher than the intervention group in the first and second days after CABG (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>According to the results, administration of remifentanil as a short-acting intraoperative opioid, and the gabapentin to treat nerve pain along with paracetamol before and after CABG surgery could effectively control pain and hemodynamic stability of patients with the least side effects besides reducing the need for additional opioids.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/abr.abr_192_24","type":"journal-article","created":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T18:00:26Z","timestamp":1793210426000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Coronary Artery Bypass Grafting Using Two Different Anesthetic Techniques: Postoperative Outcome"],"prefix":"10.4103","volume":"15","author":[{"given":"Mojtaba","family":"Mansouri","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gholamreza","family":"Massoumi","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Anesthesiology and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, Iran, Department of Surgery, Isfahan University of Medical Science, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohsen","family":"MirMohammad-Sadeghi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Mir-Mohammad Sadeghi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi","family":"Shafizadeh","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,5]]},"reference":[{"key":"R1-20261028","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1016\/j.hlc.2020.12.009","article-title":"Location and patterns of persistent pain following cardiac surgery","volume":"30","author":"Katijjahbe","year":"2021","journal-title":"Heart Lung Circ"},{"key":"R2-20261028","doi-asserted-by":"crossref","first-page":"200","DOI":"10.4103\/aca.ACA_241_18","article-title":"Pain relief following sternotomy in conventional cardiac surgery: A review of non-neuraxial regional nerve blocks","volume":"23","author":"Kar","year":"2020","journal-title":"Ann Card Anaesth"},{"key":"R3-20261028","first-page":"373","article-title":"Study of patient pain management after heart surgery","volume":"3","author":"Sattari","year":"2013","journal-title":"Adv Pharm Bull"},{"key":"R4-20261028","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1111\/ors.12073","article-title":"Non\u2010steroidal anti\u2010inflammatory drugs for pain after oral surgery","volume":"7","author":"Bailey","year":"2014","journal-title":"Oral Surg"},{"key":"R5-20261028","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1177\/0003134820952834","article-title":"Are NSAIDs safe? 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