{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:25:39Z","timestamp":1787775939349,"version":"build-2784847793"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Irritable bowel syndrome (IBS) is one of the most common disorders among young adults. Various studies have demonstrated that the use of probiotics can reduce the overall symptom of IBS, and thus, our aim was to evaluate the efficacy of probiotic products in the reduction of IBS syndrome after colonoscopy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      Our patients were divided among three groups, including immediate probiotic users, start use of probiotics 1 month after colonoscopy, and placebo group. All the patients were interviewed for having common IBS symptoms (stool consistency and frequency, gas, abdominal pain, and flatulence) at baseline, 3\n                      <jats:sup>rd<\/jats:sup>\n                      month of follow-up, and 6\n                      <jats:sup>th<\/jats:sup>\n                      month of follow-up.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mean reduction in abdominal pain was 3.05 \u00b1 1.21, 3.86 \u00b1 0.94, and 3.82 \u00b1 0.63 in the control group, immediate probiotic users, and 1 month after colonoscopy, respectively (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). The symptoms of the disease, such as stool consistency, the frequency of defecation, and flatulence (except gas) in the first quarter, in the two treatment groups were significantly improved more than in the control group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05). In contrast, the frequency of defecation was not significantly different in the treatment group receiving the probiotics month after colonoscopy compared to the placebo users (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &gt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>According to our results, the use of probiotics had the beneficial effect on IBS symptoms. Furthermore, it can be said that reductions in symptoms and pain in the two treatment groups were not significantly different, but after 6 months of treatment, the effect of probiotics in patients who immediately use it after colonoscopy was more visible and more stable.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/abr.abr_216_17","type":"journal-article","created":{"date-parts":[[2018,6,25]],"date-time":"2018-06-25T06:15:25Z","timestamp":1529907325000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":12,"title":["Effect of Probiotic Administration Immediately and 1 Month after Colonoscopy in Diarrhea-predominant Irritable Bowel Syndrome Patients"],"prefix":"10.4103","volume":"7","author":[{"given":"Mahsa","family":"Khodadoostan","sequence":"first","affiliation":[{"name":"From the Department of Gastroentrology and Hebatology, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad","family":"Shavakhi","sequence":"additional","affiliation":[{"name":"From the Department of Gastroentrology and Hebatology, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Sherafat","sequence":"additional","affiliation":[{"name":"From the Department of Gastroentrology and Hebatology, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alireza","family":"Shavakhi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine School of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2018,6,25]]},"reference":[{"key":"R1-20251008","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.bpg.2010.12.010","article-title":"Epidemiology of constipation in children and adults: A systematic review","volume":"25","author":"Mugie","year":"2011","journal-title":"Best Pract Res Clin Gastroenterol"},{"key":"R2-20251008","doi-asserted-by":"crossref","first-page":"21","DOI":"10.2165\/00019053-200624010-00002","article-title":"Costs of irritable bowel syndrome in the UK and US","volume":"24","author":"Maxion-Bergemann","year":"2006","journal-title":"Pharmacoeconomics"},{"key":"R3-20251008","doi-asserted-by":"crossref","first-page":"S98","DOI":"10.1097\/MCG.0b013e31821fbf44","article-title":"Quality of life in patients with irritable bowel syndrome","volume":"45","author":"M\u00f6nnikes","year":"2011","journal-title":"J Clin Gastroenterol"},{"key":"R4-20251008","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1177\/0148607114545329","article-title":"Irritable bowel syndrome: Contemporary nutrition management strategies","volume":"38","author":"Mullin","year":"2014","journal-title":"JPEN J Parenter Enteral Nutr"},{"key":"R5-20251008","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1038\/ajg.2011.201","article-title":"Severity in irritable bowel syndrome: A Rome foundation working team report","volume":"106","author":"Drossman","year":"2011","journal-title":"Am J Gastroenterol"},{"key":"R6-20251008","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.gtc.2010.12.004","article-title":"Traditional thoughts on the pathophysiology of irritable bowel syndrome","volume":"40","author":"Hasler","year":"2011","journal-title":"Gastroenterol Clin North Am"},{"key":"R7-20251008","doi-asserted-by":"crossref","first-page":"G1075","DOI":"10.1152\/ajpgi.00537.2011","article-title":"Irritable bowel syndrome: Methods, mechanisms, and pathophysiology. 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