{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T21:38:45Z","timestamp":1788817125772,"version":"build-2803163510"},"reference-count":34,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Background:<\/jats:title>\n Bloodstream infections (BSIs) are one of the causes of morbidity and mortality in hospitalised patients. This study evaluated BSI's incidence, trend, antimicrobial susceptibility patterns and mortality in AL Zahra Hospital in Isfahan, Iran.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n This retrospective study was conducted in AL Zahra Hospital from March 2017 to March 2021. The Iranian nosocomial infection surveillance system was used for data gathering. The data included demographic and hospital data, type of bacteria, and antibiotic susceptibility findings and were analysed in SPSS-18 software.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The incidence of BSIs was 1.67% and 0.47%, and the mortality was 30% and 15.2% in the intensive care unit (ICU) and non-ICU wards, respectively. In the ICU, the mortality was correlated with the use of the catheter, type of organism and year of study, but in non-ICU, correlated with age, gender, use of the catheter, ward, year of study and duration between the incidence of BSIs and discharging\/death.\n Staphylococcus epidermidis<\/jats:italic>\n ,\n Acinetobacter<\/jats:italic>\n spp. and\n Klebsiella<\/jats:italic>\n spp. were the most frequent germs isolated in all wards. Vancomycin (63.6%) and Gentamycin (37.7%) for ICU and Vancomycin (55.6%) and Meropenem (53.3) for other wards were the most sensitive antibiotics.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Despite the few rate of BSI in the last four years in AL Zahra Hospital, our data showed that its incidence and mortality in the ICU ward are significantly more than in other hospital wards. We recommend prospective multicentre studies to know the total incidence of BSI, local risk factors and patterns of pathogens causing BSI.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/abr.abr_320_22","type":"journal-article","created":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T07:04:32Z","timestamp":1682579072000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":9,"title":["Epidemiology of Bloodstream Infections and Antimicrobial Susceptibility Pattern in ICU and Non-ICU Wards: A Four-Year Retrospective Study in Isfahan, Iran"],"prefix":"10.4103","volume":"12","author":[{"given":"Nazila","family":"Kassaian","sequence":"first","affiliation":[{"name":"Nosocomial Infection Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shadnosh","family":"Nematbakhsh","sequence":"additional","affiliation":[{"name":"Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammadreza","family":"Yazdani","sequence":"additional","affiliation":[{"name":"Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soodabeh","family":"Rostami","sequence":"additional","affiliation":[{"name":"Nosocomial Infection Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zary","family":"Nokhodian","sequence":"additional","affiliation":[{"name":"Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Behrooz","family":"Ataei","sequence":"additional","affiliation":[{"name":"Nosocomial Infection Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,4]]},"reference":[{"key":"R1-20240830","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1016\/S1473-3099(17)30394-8","article-title":"Trends in antimicrobial resistance in bloodstream infection isolates at a large urban hospital in Malawi (1998\u20132016): A surveillance study","volume":"17","author":"Musicha","year":"2017","journal-title":"Lancet Infect Dis"},{"key":"R2-20240830","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1056\/NEJMoa1306801","article-title":"Multistate point-prevalence survey of health care\u2013associated infections","volume":"370","author":"Magill","year":"2014","journal-title":"N Engl J Med"},{"key":"R3-20240830","doi-asserted-by":"crossref","DOI":"10.1128\/microbiolspec.DMIH2-0031-2016","article-title":"Bloodstream infections","volume":"4","author":"Martinez","year":"2016","journal-title":"Microbiol Spectr"},{"key":"R4-20240830","doi-asserted-by":"crossref","first-page":"e013665","DOI":"10.1136\/bmjopen-2016-013665","article-title":"Incidence of bloodstream infections: A nationwide surveillance of acute care hospitals in Switzerland 2008\u20132014","volume":"7","author":"Buetti","year":"2017","journal-title":"BMJ Open"},{"key":"R5-20240830","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S2213-2600(18)30063-8","article-title":"The global burden of paediatric and neonatal sepsis: A systematic review","volume":"6","author":"Fleischmann-Struzek","year":"2018","journal-title":"Lancet Respir Med"},{"key":"R6-20240830","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1164\/rccm.201504-0781OC","article-title":"Assessment of global incidence and mortality of hospital-treated sepsis. 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