{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:19:18Z","timestamp":1787771958790,"version":"build-2784847793"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"Abstract<\/jats:title>\n \n Background:<\/jats:title>\n This study evaluates the effect of misoprostol alone in comparison with misoprostol with Foley catheter in preparing the cervix for induction of labor in women with premature rupture of the amniotic sac.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n This randomized clinical trial study was performed from 2017 to 2019 on 206 pregnant women with singleton pregnancy and gestational age more than 36 weeks, whose rupture of the amniotic sac had occurred less than 12 hours and had a Bishop score less than 4. These women were randomly assigned to two groups of Foley catheters with misoprostol (intervention group,\n P<\/jats:italic>\n = 103) or misoprostol alone (control group,\n P<\/jats:italic>\n = 103) to induce labor. In both groups, sublingual misoprostol (25 micrograms) was administered at intervals of 4\u20136 hours. The collected data were analyzed by SPSS.21 software.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n There is no significant difference between age and Bishop score in the two groups (\n P<\/jats:italic>\n = 0.19,\n P<\/jats:italic>\n = 0.31, respectively). Lower doses (0 to 3) of misoprostol were used in the intervention group versus 0 to 5 doses in the control group (\n P<\/jats:italic>\n = 0.001). Delivery time was shorter in the intervention group (10.83 hours vs. 13.10 hours in the control group,\n P<\/jats:italic>\n = 0.001). Also, the probability of complications such as fever, tachysystole, and hospitalization of an infant in the neonatal intensive care unit (NICU) did not increase.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n An intracervical Foley catheter with misoprostol is more effective in inducing labor in pregnancies with premature rupture of the membranes than using misoprostol alone and can be a safe and effective option.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/abr.abr_78_23","type":"journal-article","created":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T07:00:18Z","timestamp":1708930818000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Comparison of Misoprostol with Foley Catheter vs Misoprostol alone for Cervical Ripening and Induction of Labor in Patients with Premature Rupture of Membrane: A Randomized Clinical Trial Study"],"prefix":"10.4103","volume":"13","author":[{"given":"Seyyedeh Azam","family":"PoorHosseini","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masoumeh","family":"Mirteimouri","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maliheh","family":"RakhshaniFar","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyede Houra","family":"Mousavi Vahed","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fedyeh","family":"Haghollahi","sequence":"additional","affiliation":[{"name":"Vali-E- Asr Reproductive Health Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,2]]},"reference":[{"key":"R1-20240830","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.18203\/2320-1770.ijrcog20171419","article-title":"A comparative study of 25\u03bcg versus 50\u03bcg vaginal misoprostol for induction of labour at term premature rupture of membrane","volume":"6","author":"Sinha","year":"2017","journal-title":"Int J Reprod Contracept Obstet Gynecol"},{"key":"R2-20240830","doi-asserted-by":"crossref","first-page":"e165","DOI":"10.1097\/AOG.0000000000001712","article-title":"Practice Bulletin No 172: Premature rupture of membranes","volume":"128","author":"Ehsanipoor","year":"2016","journal-title":"Obstet Gynecol"},{"key":"R3-20240830","first-page":"5388","article-title":"Study of patients with premature rupture of membranes","volume":"4","author":"Ahirwar","year":"2015","journal-title":"J of Evolution of Med and Dent Sci"},{"key":"R4-20240830","doi-asserted-by":"crossref","first-page":"202","DOI":"10.18203\/2320-1770.ijrcog20151625","article-title":"A comparative study between PGE1 and PGE 2 for induction of labour in premature rupture of membrane at term","volume":"5","author":"Oza","year":"2016","journal-title":"Int J Reprod Contracept Obstet Gynecol"},{"key":"R5-20240830","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1056\/NEJM199604183341601","article-title":"Induction of labor compared with expectant management for prelabor rupture of the membranes at term","volume":"334","author":"Hannah","year":"1996","journal-title":"TERMPROM Study Group. N Engl J Med"},{"key":"R7-20240830","first-page":"40","article-title":"Comparative study of intra-cervical foley catheter and vaginal misoprostol for pre-induction cervical ripening","volume":"3","author":"Fareed","year":"2015","journal-title":"IJSS"},{"key":"R8-20240830","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1186\/s13063-017-2106-1","article-title":"Evaluation of a bespoke training to increase uptake by midwifery teams of NICE Guidance for membrane sweeping to reduce induction of labour: A stepped wedge cluster randomised design","volume":"18","author":"Kenyon","year":"2017","journal-title":"Trials"},{"key":"R9-20240830","doi-asserted-by":"crossref","first-page":"360.e1","DOI":"10.1016\/j.ajog.2017.04.038","article-title":"A randomized trial of Foley bulb for labor induction in premature rupture of membranes in nulliparas (FLIP)","volume":"217","author":"Amorosa","year":"2017","journal-title":"Am J Obstet Gynecol"},{"key":"R10-20240830","doi-asserted-by":"crossref","first-page":"114","DOI":"10.4103\/1596-3519.188890","article-title":"Induction to delivery interval using transcervical Foley catheter plus oxytocin and vaginal misoprostol: A comparative study at Aminu Kano Teaching Hospital, Kano, Nigeria","volume":"15","author":"Garba","year":"2016","journal-title":"Ann Afr Med"},{"key":"R11-20240830","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15436\/2380-5595.15.015","article-title":"Cervical ripening with an osmotic dilator (Dilapan-S) in term pregnancies \u2013 An observational study","volume":"1","author":"Maier","year":"2015","journal-title":"J Gynecol Neonatal Biol"},{"key":"R12-20240830","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1055\/s-0036-1580608","article-title":"Foley catheter or oral misoprostol for induction of labor in women with term premature rupture of membranes: A randomized multicenter trial","volume":"33","author":"Kruit","year":"2016","journal-title":"Am J Perinatol"}],"container-title":["Advanced Biomedical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/abr.abr_78_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:23:02Z","timestamp":1787768582000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/abr.abr_78_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":11,"URL":"https:\/\/doi.org\/10.4103\/abr.abr_78_23","relation":{},"ISSN":["2277-9175"],"issn-type":[{"value":"2277-9175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"2023-02-26","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-31","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}