{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:37:57Z","timestamp":1787071077182,"version":"build-2736575974"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background and Aims:<\/jats:title>\n                    <jats:p>Post-sternotomy pain management remains a key concern in adult cardiac surgery. This study evaluated the efficacy and safety of ropivacaine infiltration via a presternal multi-orifice catheter for postoperative analgesia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>A prospective randomized controlled trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>A single tertiary care center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods:<\/jats:title>\n                    <jats:p>\n                      A total of 175 adult patients undergoing cardiac surgery via median sternotomy were randomized into three groups: Group A (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 58): Received 0.375% ropivacaine as continuous infusion at 5 mL\/hour, Group B (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 58): Received 5 mL of 0.375% ropivacaine as intermittent boluses every 8 hours, and Group C (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 59): Received conventional intravenous tramadol. Pain was assessed using the visual analogue scale (VAS) for 48 hours post-extubation. Intravenous tramadol was used as rescue analgesia if VAS\u22653.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Group B reported significantly lower VAS scores and rescue tramadol requirements (56 \u00b1 35 mg) compared to Group A (155 \u00b1 32 mg) and Group C (135 \u00b1 45 mg). No significant differences were observed among the groups regarding hemodynamic parameters, catheter-related infections, time to extubation, or intensive care unit (ICU) stay.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Presternal infiltration of 0.375% ropivacaine is safe and effective for post-sternotomy analgesia. The intermittent bolus technique provides superior pain relief and reduces opioid consumption compared to continuous infusion and standard intravenous analgesia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/aca.aca_181_25","type":"journal-article","created":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T16:00:08Z","timestamp":1768579208000},"page":"104-109","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy of Ropivacaine Infiltration by Presternal Multi-orifice Catheter for Post-Sternotomy Pain Relief in Adult Patients Undergoing Cardiac Surgery\u2014A Prospective, Randomized, Control Study"],"prefix":"10.4103","volume":"29","author":[{"given":"L. S. Naga","family":"Swetha","sequence":"first","affiliation":[{"name":"Department of Cardiac Anesthesia and Critical Care, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohit","family":"Prakash","sequence":"additional","affiliation":[{"name":"Department of Cardiac Anesthesia and Critical Care, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suruchi","family":"Hasija","sequence":"additional","affiliation":[{"name":"Department of Cardiac Anesthesia and Critical Care, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B Sushama","family":"Gayatri","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery, All India Institute of Medical Sciences, New Delhi, 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