{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:30:34Z","timestamp":1787758234492,"version":"build-2784847793"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Transfusion rates in cardiac surgery are high.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To determine if intraoperative autologous blood removal without volume replacement is associated with fewer homologous blood transfusions without increasing acute kidney injury.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting and Design:<\/jats:title>\n                    <jats:p>Retrospective, comparative study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Adult patients undergoing cardiac surgery, excluding those who underwent ventricular assist device surgery, heart transplants, or cardiac surgery without cardiopulmonary bypass were excluded, who had 1\u20133 units of intraoperative autologous blood removal were compared to patients without blood removal for determination of volume replacement, vasopressor support, acute kidney injury, and transfusions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Autologous blood removal was associated with fewer patients receiving homologous transfusions: intraoperative red cell transfusions fell from 75% (Control) to 48% (1 unit removed), 40% (2 units), and 30% (3 units),\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001. Total intraoperative and postoperative homologous RBC units transfused were lower in the blood removal groups: median (interquartile range) 3 (1, 6) in Control patients and 0 (0, 2), 0 (0, 2) and 0 (0, 1) in the 1, 2, and 3 units removed groups,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001. Similarly, plasma, platelet, and cryoprecipitate transfusions decreased. After adjustment for confounders, increased amounts of autologous blood removal were associated with increased intravenous fluids, only when 2 units were removed, and trivially increased vasopressor use. However, it was not associated with acidosis or acute kidney injury.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Intraoperative autologous blood removal without volume replacement of 1\u20133 units for later autologous transfusion is associated with decreased homologous transfusions without acidosis or acute kidney injury.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/aca.aca_30_21","type":"journal-article","created":{"date-parts":[[2022,10,7]],"date-time":"2022-10-07T10:50:57Z","timestamp":1665139857000},"page":"399-407","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Intraoperative Blood Collection Without Fluid Replacement for Cardiac Surgery \u2013 A Retrospective Analysis"],"prefix":"10.4103","volume":"25","author":[{"given":"Jennifer L.","family":"Vance","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Irwin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth S.","family":"Jewell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milo","family":"Engoren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-3-20240901","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1111\/j.1540-8191.2007.00428.x","article-title":"Bloodless cardiac surgery is associated with decreased morbidity and mortality","volume":"22","author":"Whitson","year":"2007","journal-title":"J Card Surg"},{"key":"R2-3-20240901","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1056\/NEJMoa1711818","article-title":"Restrictive or liberal red-cell transfusion for cardiac surgery","volume":"377","author":"Mazer","year":"2017","journal-title":"N Engl J Med"},{"key":"R3-3-20240901","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1016\/S0003-4975(02)03766-9","article-title":"Effect of blood transfusion on long-term survival after cardiac operation","volume":"74","author":"Engoren","year":"2002","journal-title":"Ann Thorac Surg"},{"key":"R4-3-20240901","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1056\/NEJMoa070403","article-title":"Duration of red-cell storage and complications after cardiac surgery","volume":"358","author":"Koch","year":"2008","journal-title":"N Engl J Med"},{"key":"R5-3-20240901","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/S1010-7940(96)80338-1","article-title":"Cardiopulmonary bypass leads to preferential loss of activated platelets. 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