{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:48:58Z","timestamp":1787071738721,"version":"build-2736575974"},"reference-count":4,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:p>Hypernatremia is a condition that can lead to severe neurological symptoms, including flaccid paralysis, cognitive impairment, encephalopathy, and coma. Osmotic demyelination syndrome (ODS), which encompasses central pontine myelinolysis and extrapontine myelinolysis (EPM), is a known complication of the rapid correction of sodium levels. Limited data exist on the occurrence of ODS in post-partum women, particularly those with hypernatremia. Here, we present a case of a post-partum lady who presented in an unconscious and agitated state with hypernatremia and was found to have imaging characteristics consistent with hypernatremic demyelination. Despite a moderately elevated sodium level, she exhibited typical symptoms and imaging findings of EPM. While previously reported cases often involve patients with significantly higher sodium levels, this case highlights the importance of maintaining a low threshold for suspicion of ODS, particularly in post-partum women with hypernatremia, to prevent catastrophic consequences.<\/jats:p>","DOI":"10.4103\/aian.aian_567_25","type":"journal-article","created":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T05:00:09Z","timestamp":1765170009000},"page":"898-900","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["An Unusual Case of Extrapontine Myelinolysis in a Post-partum Woman with Hypernatremia"],"prefix":"10.4103","volume":"28","author":[{"given":"Abhishek","family":"Rathore","sequence":"first","affiliation":[{"name":"Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atchayaram","family":"Nalini","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Netravathi","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravi","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravindranadh C","family":"Mundlamuri","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seena","family":"Vengalil","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pritam","family":"Raja","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,12,6]]},"reference":[{"key":"R1-20251222","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.jns.2010.01.014","article-title":"Seasonal post-partum hypernatremic encephalopathy with osmotic extrapontine myelinolysis and rhabdomyolysis","volume":"291","author":"Naik","year":"2010","journal-title":"J Neurol Sci"},{"key":"R2-20251222","first-page":"1","article-title":"Assessment of cultural beliefs and practices during the postnatal period in a coastal town of South India: Mixed-method research study","volume":"3","author":"Rao","year":"2014","journal-title":"Glob J Med Public Health"},{"key":"R3-20251222","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1056\/NEJM198402163100707","article-title":"Transient vasopressin-resistant diabetes insipidus of pregnancy","volume":"310","author":"Barron","year":"1984","journal-title":"N Engl J Med"},{"key":"R4-20251222","doi-asserted-by":"crossref","first-page":"106","DOI":"10.4103\/0972-2327.107719","article-title":"\u2032Wine Glass\u2032 sign in recurrent post-partum hypernatremic osmotic cerebral demyelination","volume":"16","author":"Saroja","year":"2013","journal-title":"Ann Indian Acad Neurol"}],"container-title":["Annals of Indian Academy of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/aian.aian_567_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:52:59Z","timestamp":1787068379000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aian.aian_567_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":4,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/aian.aian_567_25","relation":{},"ISSN":["0972-2327","1998-3549"],"issn-type":[{"value":"0972-2327","type":"print"},{"value":"1998-3549","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"2025-06-11","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-01","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}