{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T13:41:39Z","timestamp":1786714899043,"version":"build-2736575974"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asian J Androl"],"published-print":{"date-parts":[[2018]]},"DOI":"10.4103\/aja.aja_8_17","type":"journal-article","created":{"date-parts":[[2017,4,5]],"date-time":"2017-04-05T03:21:00Z","timestamp":1491362460000},"page":"24","source":"Crossref","is-referenced-by-count":9,"title":["Aldosterone induces inflammatory cytokines in penile corpus cavernosum by activating the NF-\u03baB pathway"],"prefix":"10.4103","volume":"20","author":[{"given":"Qiang","family":"Ding","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zu-Quan","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan-Hua","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Meng","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian-Qing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao-Wen","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/1008-682X.203807-1","first-page":"57","volume-title":"Prevalence and correlates of erectile dysfunction by race and ethnicity among men aged 40 or older in the United States: from the male attitudes regarding sexual health survey","author":"Laumann","year":"2007","journal-title":"J Sex Med"},{"key":"key-10.4103\/1008-682X.203807-2","first-page":"54","volume-title":"Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study","author":"Feldman","year":"1994","journal-title":"J Urol"},{"key":"key-10.4103\/1008-682X.203807-3","first-page":"S46","volume-title":"Erectile dysfunction in the cardiac patient: how common and should we treat?","author":"Kloner","year":"2003","journal-title":"J Urol"},{"key":"key-10.4103\/1008-682X.203807-4","first-page":"32","volume-title":"Prevalence of erectile dysfunction and associated factors in Korean older adults with coronary artery disease","author":"Son","year":"2016","journal-title":"J Gerontol Nurs"},{"key":"key-10.4103\/1008-682X.203807-5","first-page":"411","volume-title":"Pathophysiology of erectile dysfunction","author":"Matsui","year":"2015","journal-title":"Curr Drug Targets"},{"key":"key-10.4103\/1008-682X.203807-6","first-page":"3823","volume-title":"Emerging role for TNF-alpha in erectile dysfunction","author":"Carneiro","year":"2010","journal-title":"J Sex Med"},{"key":"key-10.4103\/1008-682X.203807-7","first-page":"872","volume-title":"The association between TNF-alpha and erectile dysfunction complaints","author":"Matos","year":"2013","journal-title":"Andrology"},{"key":"key-10.4103\/1008-682X.203807-8","first-page":"311","volume-title":"TNF-alpha infusion impairs corpora cavernosa reactivity","author":"Carneiro","year":"2009","journal-title":"J Sex Med"},{"key":"key-10.4103\/1008-682X.203807-9","first-page":"49","volume-title":"TNF biology, pathogenic mechanisms and emerging therapeutic strategies","author":"Kalliolias","year":"2016","journal-title":"Nat Rev Rheumatol"},{"key":"key-10.4103\/1008-682X.203807-10","first-page":"a000158","volume-title":"The IKK complex, a central regulator of NF-kappaB activation","author":"Israel","year":"2010","journal-title":"Cold Spring Harb Perspect Biol"},{"key":"key-10.4103\/1008-682X.203807-11","first-page":"313","volume-title":"Linear ubiquitination-mediated NF-\u03baB regulation and its related disorders","author":"Tokunaga","year":"2013","journal-title":"J Biochem"},{"key":"key-10.4103\/1008-682X.203807-12","first-page":"77","volume-title":"Regulation of NF-\u03baB by ubiquitination and degradation of the I\u03baBs","author":"Kanarek","year":"2012","journal-title":"Immunol Rev"},{"key":"key-10.4103\/1008-682X.203807-13","first-page":"1326","volume-title":"On the mechanism of action of aldosterone on sodium transport: the role of RNA synthesis","author":"Porter","year":"1964","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key-10.4103\/1008-682X.203807-14","first-page":"999","volume-title":"Elevated plasma aldosterone is an independent risk factor for erectile dysfunction in men","author":"Wu","year":"2016","journal-title":"World J Urol"},{"key":"key-10.4103\/1008-682X.203807-15","first-page":"500","volume-title":"Effect of aldosterone on isolated human penile corpus cavernosum tissue","author":"Muguruma","year":"2008","journal-title":"BJU Int"},{"key":"key-10.4103\/1008-682X.203807-16","first-page":"21","volume-title":"Mineralocorticoid receptor expression in human penile corpus cavernosum","author":"Kishimoto","year":"2013","journal-title":"J Med Invest"},{"key":"key-10.4103\/1008-682X.203807-17","first-page":"2773","volume-title":"Up-regulation of VEGF by small activator RNA in human corpus cavernosum smooth muscle cells","author":"Chen","year":"2011","journal-title":"J Sex Med"},{"key":"key-10.4103\/1008-682X.203807-18","first-page":"1289","volume-title":"SCF(\u03b2-TRCP) suppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2","author":"Shaik","year":"2012","journal-title":"J Exp Med"},{"key":"key-10.4103\/1008-682X.203807-19","doi-asserted-by":"crossref","unstructured":"Shao R, Guo X. Human microvascular endothelial cells immortalized with human telomerase catalytic protein: a model for the study of in vitro angiogenesis. Biochem Biophys Res Commun 2004; 321: 788-94.","DOI":"10.1016\/j.bbrc.2004.07.033"},{"key":"key-10.4103\/1008-682X.203807-20","first-page":"5789","volume-title":"High mobility group box 1 protein is methylated and transported to cytoplasm in clear cell renal cell carcinoma","author":"Wu","year":"2013","journal-title":"Asian Pac J Cancer Prev"},{"key":"key-10.4103\/1008-682X.203807-21","first-page":"434","volume-title":"SCF (Fbw7) modulates the NF\u03baB signaling pathway by targeting NF\u03baB2 for ubiquitination and destruction","author":"Fukushima","year":"2012","journal-title":"Cell Rep"},{"key":"key-10.4103\/1008-682X.203807-22","first-page":"414","volume-title":"Noncanonical NF-\u03baB signaling in health and disease","author":"Cildir","year":"2016","journal-title":"Trends Mol Med"},{"key":"key-10.4103\/1008-682X.203807-23","first-page":"125","volume-title":"The noncanonical NF-\u03baB pathway","author":"Sun","year":"2012","journal-title":"Immunol Rev"},{"key":"key-10.4103\/1008-682X.203807-24","first-page":"1782","volume-title":"Anti-inflammatory therapies for cardiovascular disease","author":"Ridker","year":"2014","journal-title":"Eur Heart J"},{"key":"key-10.4103\/1008-682X.203807-25","first-page":"621","volume-title":"Drugs targeting the renin-angiotensin-aldosterone system","author":"Zaman","year":"2002","journal-title":"Nat Rev Drug Discov"},{"key":"key-10.4103\/1008-682X.203807-26","first-page":"1009","volume-title":"Aldosterone induces superoxide generation via Rac1 activation in endothelial cells","author":"Iwashima","year":"2008","journal-title":"Endocrinology"},{"key":"key-10.4103\/1008-682X.203807-27","first-page":"2213","volume-title":"Aldosterone administration to mice stimulates macrophage NADPH oxidase and increases atherosclerosis development: a possible role for angiotensin-converting enzyme and the receptors for angiotensin II and aldosterone","author":"Keidar","year":"2004","journal-title":"Circulation"},{"key":"key-10.4103\/1008-682X.203807-28","first-page":"323","volume-title":"NF-\u03baB signaling pathway and free radical impact","author":"Siomek","year":"2012","journal-title":"Acta Biochim Pol"}],"container-title":["Asian Journal of Andrology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T13:22:47Z","timestamp":1786713767000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aja.aja_8_17"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018]]}},"alternative-id":["203807"],"URL":"https:\/\/doi.org\/10.4103\/aja.aja_8_17","relation":{},"ISSN":["1008-682X"],"issn-type":[{"value":"1008-682X","type":"print"}],"subject":[],"published":{"date-parts":[[2018]]}}}