{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:20:48Z","timestamp":1787761248124,"version":"build-2784847793"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:p>\n                    To evaluate and compare the outcomes and complications of three different surgical techniques for treating primary proximal hypospadias with ventral curvature (VC) \u226530\u00b0, we retrospectively reviewed the medical records of patients who underwent primary repair of proximal hypospadias with VC \u226530\u00b0 after degloving at Beijing Children\u2019s Hospital Affiliated to Capital Medical University (Beijing, China) from January 2019 to January 2021. A total of 152 patients were divided into three groups: transverse preputial island flap (TPIF) combined with Duplay, modified Koyanagi, and staged TPIF, which were performed on 55, 16, and 81 patients, respectively. A total of 39 (25.7%) patients had complications. Complications rates were similar for the TPIF combined with the Duplay group (40.0%) and modified Koyanagi group (50.0%) but lower for the staged TPIF group (11.1%;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; 0.01). The incidence of urethrocutaneous fistulas was significantly higher in TPIF combined with Duplay group (21.8%) compared to staged TPIF group (4.9%;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = 0.01). In univariate analysis, the length of the urethral defect was the single factor that could predict complications; the cutoff was 4.55 cm. More patients in the long urethral defect group than in the short one had complications (34.1% vs 15.7%,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = 0.01). These results indicate that staged TPIF produced a better outcome, whereas more patients in the TPIF combined with Duplay group presented with two or more complications.\n                  <\/jats:p>","DOI":"10.4103\/aja2022106","type":"journal-article","created":{"date-parts":[[2023,1,3]],"date-time":"2023-01-03T03:32:40Z","timestamp":1672716760000},"page":"616-620","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Comparison of outcomes in three surgical techniques for proximal hypospadias: staged transverse preputial island flap urethroplasty versus single-stage repairs"],"prefix":"10.4103","volume":"25","author":[{"given":"Yu-Si","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Urology, Beijing Children\u2019s Hospital Affiliated to Capital Medical University, National Center for Children\u2019s Health, Beijing 100045, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Cheng","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Urology, Beijing Children\u2019s Hospital Affiliated to Capital Medical University, National Center for Children\u2019s Health, Beijing 100045, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Urology, Beijing Children\u2019s Hospital Affiliated to Capital Medical University, National Center for Children\u2019s Health, Beijing 100045, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Wei","family":"Fang","sequence":"additional","affiliation":[{"name":"Department of Urology, Beijing Children\u2019s Hospital Affiliated to Capital Medical University, National Center for Children\u2019s Health, Beijing 100045, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Ping","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Urology, Beijing Children\u2019s Hospital Affiliated to Capital Medical University, National Center for Children\u2019s Health, Beijing 100045, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,1,3]]},"reference":[{"key":"R1-20240829","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1016\/j.juro.2016.11.054","article-title":"Intermediate-term followup of proximal hypospadias repair reveals high complication rate","volume":"197","author":"Long","year":"2017","journal-title":"J Urol"},{"key":"R2-20240829","doi-asserted-by":"crossref","first-page":"28.e1","DOI":"10.1016\/j.jpurol.2015.06.011","article-title":"Proximal hypospadias: a persistent challenge. Single institution outcome analysis of three surgical techniques over a 10-year period","volume":"12","author":"Pippi Salle","year":"2016","journal-title":"J Pediatr Urol"},{"key":"R3-20240829","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.juro.2015.02.044","article-title":"Complications following staged hypospadias repair using transposed preputial skin flaps","volume":"194","author":"Stanasel","year":"2015","journal-title":"J Urol"},{"key":"R4-20240829","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/S0094-0143(21)01243-X","article-title":"Transverse preputial island flap technique for repair of severe hypospadias","volume":"7","author":"Duckett","year":"1980","journal-title":"Urol Clin North Am"},{"key":"R5-20240829","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.jpurol.2006.06.007","article-title":"Neo-modified Koyanagi technique for the single-stage repair of proximal hypospadias","volume":"3","author":"Hayashi","year":"2007","journal-title":"J Pediatr Urol"},{"issue":"Suppl 3","key":"R6-20240829","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/j.1464-410X.1995.tb07815.x","article-title":"Hypospadias repair: the two-stage alternative","volume":"76","author":"Bracka","year":"1995","journal-title":"Br J Urol"},{"key":"R7-20240829","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1016\/j.juro.2016.05.098","article-title":"The effect of staged transverse preputial island flap urethroplasty for proximal hypospadias with severe chordee","volume":"196","author":"Chen","year":"2016","journal-title":"J Urol"},{"key":"R8-20240829","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1016\/j.eururo.2011.08.031","article-title":"Trends in hypospadias surgery: results of a worldwide survey","volume":"60","author":"Springer","year":"2011","journal-title":"Eur Urol"},{"key":"R9-20240829","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1016\/j.jpurol.2013.04.008","article-title":"Current practice in paediatric hypospadias surgery;a specialist survey","volume":"9","author":"Steven","year":"2013","journal-title":"J Pediatr Urol"},{"key":"R10-20240829","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.jpurol.2017.03.024","article-title":"Current challenges with proximal hypospadias: we have a long way to go","volume":"13","author":"Gong","year":"2017","journal-title":"J Pediatr Urol"},{"key":"R11-20240829","doi-asserted-by":"crossref","first-page":"196.e1","DOI":"10.1016\/j.jpurol.2016.05.002","article-title":"Hypospadias: are we as good as we think when we correct proximal hypospadias?","volume":"12","author":"Long","year":"2016","journal-title":"J Pediatr Urol"},{"key":"R12-20240829","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1007\/s00383-019-04480-7","article-title":"Staged transverse preputial island flap urethroplasty for proximal hypospadias: a single-center experience","volume":"35","author":"Wang","year":"2019","journal-title":"Pediatr Surg Int"},{"key":"R13-20240829","doi-asserted-by":"crossref","first-page":"344.e1","DOI":"10.1016\/j.jpurol.2019.03.028","article-title":"Persistent or recurrent ventral curvature after failed proximal hypospadias repair","volume":"15","author":"Snodgrass","year":"2019","journal-title":"J Pediatr Urol"},{"key":"R14-20240829","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s11934-015-0543-5","article-title":"Surgery for primary proximal hypospadias with ventral curvature >30 degrees","volume":"16","author":"Snodgrass","year":"2015","journal-title":"Curr Urol Rep"},{"key":"R15-20240829","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.jpurol.2021.05.014","article-title":"Meta-analysis comparing the outcomes of single stage (foreskin pedicled tube) versus two stage (foreskin free graft &foreskin pedicled flap) repair for proximal hypospadias in the last decade","volume":"17","author":"Babu","year":"2021","journal-title":"J Pediatr Urol"},{"key":"R16-20240829","doi-asserted-by":"crossref","first-page":"28.e1","DOI":"10.1016\/j.jpurol.2017.07.007","article-title":"Posterior hypospadias: evaluation of a paradigm shift from single to staged repair","volume":"14","author":"Badawy","year":"2018","journal-title":"J Pediatr Urol"},{"key":"R17-20240829","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/S0022-5347(17)44185-1","article-title":"Acquired megalourethra: an uncommon complication of the transverse preputial island flap urethroplasty","volume":"137","author":"Aigen","year":"1987","journal-title":"J Urol"},{"key":"R18-20240829","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.urology.2020.11.058","article-title":"Koyanagi-Snow-Hayashi urethroplasty in severe hypospadias repair: between hope and reality","volume":"152","author":"Acimi","year":"2021","journal-title":"Urology"},{"key":"R19-20240829","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1007\/s00345-018-2350-3","article-title":"Patients with disorders of sex development and proximal hypospadias are at high risk for reoperation","volume":"36","author":"Saltzman","year":"2018","journal-title":"World J Urol"},{"key":"R20-20240829","doi-asserted-by":"crossref","first-page":"286.e1","DOI":"10.1016\/j.jpurol.2016.02.014","article-title":"Two-stage graft urethroplasty for proximal and complicated hypospadias in children: a retrospective study","volume":"12","author":"Faure","year":"2016","journal-title":"J Pediatr Urol"},{"key":"R21-20240829","doi-asserted-by":"crossref","first-page":"354.e1","DOI":"10.1016\/j.jpurol.2017.05.017","article-title":"Early vs late-presenting urethroplasty complications after hypospadias repair: a retrospective analysis of patient follow-up","volume":"13","author":"Faasse","year":"2017","journal-title":"J Pediatr Urol"}],"container-title":["Asian Journal of Andrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/aja2022106","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:29:54Z","timestamp":1787758194000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aja2022106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,3]]},"references-count":21,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/aja2022106","relation":{},"ISSN":["1745-7262","1008-682X"],"issn-type":[{"value":"1745-7262","type":"print"},{"value":"1008-682X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,3]]},"assertion":[{"value":"2022-06-27","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-24","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}