{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T13:17:57Z","timestamp":1789132677441,"version":"build-2803163510"},"reference-count":42,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:p>\n                    The authors performed a comprehensive review of current literature to create a model comparing commonly evaluated variables in male factor infertility, for example, follicle-stimulating hormone (FSH), testicular volume (TV), and testosterone (T), to better predict sperm retrieval rate (SRR). Twenty-nine studies were included, 9 with data on conventional testicular sperm extraction (cTESE) for a total of 1227 patients and 20 studies including data on microdissection testicular sperm extraction (mTESE) for a total of 4760 patients. A weighted-means value of SRR, FSH, T, and TV was created, and a weighted linear regression was then used to describe associations among SRR, type of procedure, FSH, T, and TV. In this study, weighted-means values demonstrated mTESE to be superior to cTESE with an SRR of 51.9% vs 40.1%. Multiple weighted linear regressions were created to describe associations among SRR, procedure type, FSH, T, and TV. The models showed that for every 1.19 mIU ml\n                    <jats:sup>\u22121<\/jats:sup>\n                    increase in FSH, there would be a significant decrease in SRR by 1.0%. Seeking to create a more clinically relevant model, FSH values were then divided into normal, moderate elevation, and significant elevation categories (FSH &lt;10 mIU ml\n                    <jats:sup>\u22121<\/jats:sup>\n                    , 10\u201319 mIU ml\n                    <jats:sup>\u22121<\/jats:sup>\n                    , and &gt;20 mIU ml\n                    <jats:sup>\u22121<\/jats:sup>\n                    , respectively). For an index patient undergoing cTESE, the retrieval rates would be 57.1%, 44.3%, and 31.2% for values normal, moderately elevated, and significantly elevated, respectively. In conclusion, in a large meta-analysis, mTESE was shown to be more successful than cTESE for sperm retrievals. FSH has an inverse relationship to SRR in retrieval techniques and can alone be predictive of cTESE SRR.\n                  <\/jats:p>","DOI":"10.4103\/aja202221","type":"journal-article","created":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T06:46:56Z","timestamp":1653029216000},"page":"38-42","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":10,"title":["An examination of predictive markers for successful sperm extraction procedures: a linear model and systematic review"],"prefix":"10.4103","volume":"25","author":[{"given":"Nicholas","family":"Major","sequence":"first","affiliation":[{"name":"Department of Urology, Medical University of South Carolina, Charleston, SC 29425, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K Russ","family":"Edwards","sequence":"additional","affiliation":[{"name":"Department of Urology, Medical University of South Carolina, Charleston, SC 29425, 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