{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T17:30:35Z","timestamp":1786728635272,"version":"build-2736575974"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>\n                    The objective of this study was to investigate whether treatment with\n                    <jats:italic toggle=\"yes\">Tribulus terrestris<\/jats:italic>\n                    (Tt) has any impact on the testicular morphology and function in a rodent model. Twenty male rats were divided into a control group and a group receiving 100 mg kg\n                    <jats:sup>\u22121<\/jats:sup>\n                    body weight of Tt supplementation. After 40 days of experiment, the animals were submitted to euthanasia; epididymal tail spermatozoa were collected; and spermatozoa concentration, motility, and viability were analyzed. In addition, testicles were collected and processed for histomorphometrical analyses. Data were compared using the Student\u2019s\n                    <jats:italic toggle=\"yes\">t<\/jats:italic>\n                    -test and considered significant when\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; 0.05. Spermatozoa concentration, motility, and viability showed no difference between the groups. Further, testicular weight and volume, seminiferous tubule diameter, tunica propria surface density, seminiferous epithelium surface density, and intertubular compartment surface density were statistically similar between the groups. However, seminiferous epithelium height and tubular lumen surface density were augmented in animals treated with Tt. Treatment with Tt does not cause a major impact on testicular morphology, promoting only subtle modifications. No difference on spermatozoa parameters was observed.\n                  <\/jats:p>","DOI":"10.4103\/aja202340","type":"journal-article","created":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T08:00:27Z","timestamp":1692777627000},"page":"67-70","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["What is the effect of Tribulus terrestris on testicular morphology and sperm production? An experimental study in the rat model"],"prefix":"10.4103","volume":"26","author":[{"given":"Marcello Henrique Araujo","family":"Da Silva","sequence":"first","affiliation":[{"name":"Urogenital Research Unit, Rio de Janeiro State University, Rio de Janeiro 20551-030, RJ, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela Faria","family":"Buys-Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Urogenital Research Unit, Rio de Janeiro State University, Rio de Janeiro 20551-030, RJ, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o Henrique Duque Reis","family":"Estrada","sequence":"additional","affiliation":[{"name":"Urogenital Research Unit, Rio de Janeiro State University, Rio de Janeiro 20551-030, RJ, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco Jos\u00e9 Barcellos","family":"Sampaio","sequence":"additional","affiliation":[{"name":"Urogenital Research Unit, Rio de Janeiro State University, Rio de Janeiro 20551-030, RJ, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diogo Benchimol","family":"de Souza","sequence":"additional","affiliation":[{"name":"Urogenital Research Unit, Rio de Janeiro State University, Rio de Janeiro 20551-030, RJ, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,8,22]]},"reference":[{"key":"R1-20240829","doi-asserted-by":"crossref","first-page":"645","DOI":"10.4314\/ahs.v18i3.22","article-title":"Tribulus terrestris improves metronidazole-induced impaired fertility in the male mice","volume":"18","author":"Kumari","year":"2018","journal-title":"Afr Health Sci"},{"key":"R2-20240829","doi-asserted-by":"crossref","first-page":"e12655","DOI":"10.1111\/and.12655","article-title":"Effect of oral administration of Tribulus terrestris extract on semen quality and body fat index of infertile men","volume":"49","author":"Salgado","year":"2017","journal-title":"Andrologia"},{"key":"R3-20240829","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1590\/s1677-5538.ibju.2018.0843","article-title":"Improvement of fertility parameters with Tribulus terrestris and Anacyclus pyrethrum treatment in male rats","volume":"45","author":"Haghmorad","year":"2019","journal-title":"Int Braz J Urol"},{"key":"R4-20240829","doi-asserted-by":"crossref","first-page":"113","DOI":"10.5455\/jice.20140627123443","article-title":"Assessment of protective and anti-oxidant properties of Tribulus terrestris fruits against testicular toxicity in rats","volume":"3","author":"Shalaby","year":"2014","journal-title":"J Intercult Ethnopharmacol"},{"key":"R5-20240829","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1080\/19390211.2016.1188193","article-title":"Prospective analysis on the effect of botanical medicine (Tribulus terrestris) on serum testosterone level and semen parameters in males with unexplained infertility","volume":"14","author":"Roaiah","year":"2017","journal-title":"J Diet Suppl"},{"key":"R6-20240829","doi-asserted-by":"crossref","first-page":"3969","DOI":"10.3390\/nu13113969","article-title":"The effects of 6 weeks of Tribulus terrestris L. 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