{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T16:24:17Z","timestamp":1790612657569,"version":"4.1.0"},"reference-count":91,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>Peyronie\u2019s disease (PD) is characterized by abnormal penile curvature, and various surgical methods have been developed using different graft materials. However, there is currently no universal agreement on which type of graft is the best. The objective of this review was to evaluate the available literature and identify the most effective graft material for penile curvature correction in PD. A literature search was conducted using electronic databases, including PubMed, Scopus, and the Cochrane Library. The patients, intervention, comparison, and outcome (PICO) approach was used to define the eligibility of studies. Two authors independently selected studies, evaluated them, and extracted data. Random-effect models using the DerSimonian\u2013Laird method were used. Most studies were single-arm studies and had a high risk of bias. Buccal mucosa grafts (BMG) were found to result in the highest penile straightening rates and were associated with the least de novo erectile dysfunction. TachoSil grafts demonstrated a high success rate in straightening despite a higher mean preoperative curvature, while Tutoplast grafts had a higher incidence of postoperative erectile dysfunction. BMG had the highest percentage of postoperative penile straightening. Overall, the TachoSil graft showed the best performance when preoperative curvature is taken into account. Based on the available literature, BMG appear to be the most effective for penile curvature correction in PD, but this is offset by the requirement for low preoperative curvature. The TachoSil graft shows the best overall performance when preoperative curvature is considered. Comparative randomized clinical trials are still needed to determine graft superiority.<\/jats:p>","DOI":"10.4103\/aja202358","type":"journal-article","created":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T12:14:24Z","timestamp":1704802464000},"page":"250-259","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":14,"title":["Grafts in Peyronie\u2019s surgery without the use of prostheses: a systematic review and meta-analysis"],"prefix":"10.4103","volume":"26","author":[{"given":"Anastasios","family":"Natsos","sequence":"first","affiliation":[{"name":"Department of Urology, University of Patras, Patras 26500, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasileios","family":"Tatanis","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Patras, Patras 26500, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stavros","family":"Kontogiannis","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Patras, Patras 26500, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Waisbrod","sequence":"additional","affiliation":[{"name":"Uroclinic, Pfaeffikon 8808, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristiana","family":"Gkeka","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Patras, Patras 26500, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Obaidad","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Patras, Patras 26500, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelis","family":"Peteinaris","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Patras, Patras 26500, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Pagonis","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Patras, Patras 26500, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Costas","family":"Papadopoulos","sequence":"additional","affiliation":[{"name":"Department of Medical Physics, University of Patras, Patras 26500, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panagiotis","family":"Kallidonis","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Patras, Patras 26500, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evangelos","family":"Liatsikos","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Patras, Patras 26500, Greece"},{"name":"Department of Urology, Medical University of Vienna, Vienna 1090, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petros","family":"Drettas","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Patras, Patras 26500, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,1,9]]},"reference":[{"key":"R1-20240829","doi-asserted-by":"crossref","first-page":"E220","DOI":"10.1111\/j.1464-410X.2012.11590.x","article-title":"Penile length and girth restoration in severe Peyronie's disease using circular and longitudinal grafting","volume":"111","author":"Garaffa","year":"2013","journal-title":"BJU Int"},{"key":"R2-20240829","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.sxmr.2015.10.002","article-title":"The genetic basis of Peyronie disease: a review","volume":"4","author":"Herati","year":"2016","journal-title":"Sex Med Rev"},{"key":"R3-20240829","article-title":"EAU guidelines, edition. 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