{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T20:45:46Z","timestamp":1789937146994,"version":"4.0.1"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","license":[{"start":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T00:00:00Z","timestamp":1751932800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The aim of this study was to investigate the trend in testicular volume changes after orchiopexy in children with cryptorchidism. The clinical data of 854 children with cryptorchidism who underwent orchiopexy between January 2013 and December 2016 in Shenzhen Children\u2019s Hospital (Shenzhen, China) were retrospectively analyzed. The mean (standard deviation) age of the patients was 2.8 (2.5) years, and the duration of follow-up ranged from 1 year to 5 years. Ultrasonography was conducted preoperatively and postoperatively. The variables analyzed included age at the time of surgery, type of surgical procedure, laterality, preoperative testicular position, preoperative and postoperative testicular volumes, and the testicular volume ratio of them. The average testicular volumes preoperatively and at 1 year, 2 years, 3 years, and 5 years postoperatively were 0.27 ml, 0.38 ml, 0.53 ml, 0.87 ml, and 1.00 ml, respectively (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; 0.001). The corresponding testicular volume ratios were 0.67, 0.76, 0.80, 0.83, and 0.84 (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; 0.001). The mean volume of the undescended testes was significantly smaller than the mean normative value (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; 0.001, lower than the 10\n                    <jats:sup>th<\/jats:sup>\n                    percentile). The postoperative testicular volumes in children with cryptorchidism were generally lower than those in healthy boys but were still greater than the 10\n                    <jats:sup>th<\/jats:sup>\n                    percentile and exhibited an increasing trend. The older the child is at the time of surgery, the larger the gap in volume between the affected and normal testes. Although testicular volume tends to gradually increase after orchiopexy for cryptorchidism, it could not normalizes. Earlier surgery results in affected testicular volumes closer to those of healthy boys.\n                  <\/jats:p>","DOI":"10.4103\/aja202527","type":"journal-article","created":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T05:00:56Z","timestamp":1751950856000},"page":"723-727","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Trend in testicular volume change after orchiopexy in 854 children with cryptorchidism"],"prefix":"10.4103","volume":"27","author":[{"given":"Ying-Ying","family":"He","sequence":"first","affiliation":[{"name":"Department of Urology, Shenzhen Children\u2019s Hospital, China Medical University, Shenzhen 518000, China"},{"name":"Department of Urology and Laboratory of Pelvic Floor Muscle Function, Shenzhen Children\u2019s Hospital, Shenzhen 518000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-Cong","family":"Ke","sequence":"additional","affiliation":[{"name":"Department of Urology and Laboratory of Pelvic Floor Muscle Function, Shenzhen Children\u2019s Hospital, Shenzhen 518000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shou-Lin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Urology and Laboratory of Pelvic Floor Muscle Function, Shenzhen Children\u2019s Hospital, Shenzhen 518000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui-Jie","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Urology and Laboratory of Pelvic Floor Muscle Function, Shenzhen Children\u2019s Hospital, Shenzhen 518000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-Liang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Urology and Laboratory of Pelvic Floor Muscle Function, Shenzhen Children\u2019s Hospital, Shenzhen 518000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng-Yu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Urology and Laboratory of Pelvic Floor Muscle Function, Shenzhen Children\u2019s Hospital, Shenzhen 518000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wan-Hua","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Urology and Laboratory of Pelvic Floor Muscle Function, Shenzhen Children\u2019s Hospital, Shenzhen 518000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng-Hao","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Urology and Laboratory of Pelvic Floor Muscle Function, Shenzhen Children\u2019s Hospital, Shenzhen 518000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-Lin","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Urology and Laboratory of Pelvic Floor Muscle Function, Shenzhen Children\u2019s Hospital, Shenzhen 518000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,7,8]]},"reference":[{"key":"R1-20251103","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1038\/nrurol.2017.90","article-title":"Risk factors for cryptorchidism","volume":"14","author":"Gurney","year":"2017","journal-title":"Nat Rev Urol"},{"key":"R2-20251103","first-page":"677","article-title":"Utility of laparoscopic approach of orchiopexy for palpable cryptorchidism:a systematic review and meta-analysis","volume":"8","author":"Anand","year":"2021","journal-title":"Children (Basel)"},{"key":"R3-20251103","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1159\/000049841","article-title":"EAU 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History"}},{"value":"2025-04-28","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}