{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T09:13:23Z","timestamp":1788599603196,"version":"build-2803163510"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T00:00:00Z","timestamp":1771891200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:p>\n                    Peyronie\u2019s disease (PD) is a debilitating condition affecting the sexual and psychological health of millions of men and their partners around the world. Plaque incision (PI) surgery with buccal mucosa graft (BMG) is a promising option for patients with PD. This systematic review aims to comprehensively assess the efficacy of PI with BMG in the management of PD. PubMed, Scopus, Web of Science, Embase, CENTRAL, and Clinicaltrials.gov were systematically searched for possible keywords to include full-text studies and abstracts. After full-text screening and extraction, the quality of included studies was assessed using the National Institutes of Health (NIH) study quality assessment tools. Open Meta-Analyst software was used with a random effect model for all analyses. Seventeen reports were included in the current systematic review, including nine full-text reports and eight abstracts. Meta-analysis of the included data revealed that PI with BMG showed a success rate of 98.6%, a satisfaction rate of 92.1%, and a very low\n                    <jats:italic toggle=\"yes\">de novo<\/jats:italic>\n                    erectile dysfunction rate of 1.7%, with a penile shortening rate of 1.1%. The International Index of Erectile Dysfunction and the length of the affected side significantly increased by 1.69 points and 1.99 cm, respectively. Head-to-head analysis showed comparable outcomes between BMG and other grafting methods. PI with BMG seems to be an effective treatment for PD with comparable potential to other grafting methods. Further randomized clinical trials are needed to evaluate the efficacy of PI with BMG in comparison to other grafting techniques.\n                  <\/jats:p>","DOI":"10.4103\/aja202543","type":"journal-article","created":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T06:00:24Z","timestamp":1771999224000},"page":"485-492","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Surgical treatment of Peyronie\u2019s disease by plaque incision and buccal mucosa graft: a systematic review and meta-analysis"],"prefix":"10.4103","volume":"28","author":[{"given":"Hattan","family":"Badr","sequence":"first","affiliation":[{"name":"Department of Urology and Reconstructive Andrology, Humanitas Gradenigo Hospital, Turin 10121-10156, Italy"},{"name":"Department of Surgery, Division of Urology, King Abdullah Medical City, Mecca 24231, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Bettocchi","sequence":"additional","affiliation":[{"name":"Andrology Unit, Department of Urology and Renal Transplantation, University of Foggia, Foggia 71121-71122, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulrahman","family":"Alsalem","sequence":"additional","affiliation":[{"name":"Department of Urology and Reconstructive Andrology, Humanitas Gradenigo Hospital, Turin 10121-10156, Italy"},{"name":"Department of Surgery, Urology Unit, Farwaniya Hospital, Kuwait City 85600, Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Ricapito","sequence":"additional","affiliation":[{"name":"Andrology Unit, Department of Urology and Renal Transplantation, University of Foggia, Foggia 71121-71122, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Rubino","sequence":"additional","affiliation":[{"name":"Andrology Unit, Department of Urology and Renal Transplantation, University of Foggia, Foggia 71121-71122, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicol\u00f2","family":"Buffi","sequence":"additional","affiliation":[{"name":"Department of Urology, IRCCS Humanitas Research Hospital, Rozzano, Milan 20121-20162, Italy"},{"name":"Department of Biomedical Science, Humanitas University, Rozzano, Milan 20121-20162, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Gobbo","sequence":"additional","affiliation":[{"name":"Department of Urology and Reconstructive Andrology, Humanitas Gradenigo Hospital, Turin 10121-10156, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Ralph","sequence":"additional","affiliation":[{"name":"Institute of Urology, University College London Hospital, London WC1E 6BT, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omid","family":"Sedigh","sequence":"additional","affiliation":[{"name":"Department of Urology and Reconstructive Andrology, Humanitas Gradenigo Hospital, Turin 10121-10156, Italy"},{"name":"Department of Biomedical Science, Humanitas University, Rozzano, Milan 20121-20162, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,2,24]]},"reference":[{"key":"R2-20260905","doi-asserted-by":"crossref","first-page":"280","DOI":"10.21037\/tau.2016.04.05","article-title":"Peyronie's disease: a literature review on epidemiology, genetics, pathophysiology, diagnosis and work-up","volume":"5","author":"Al-Thakafi","year":"2016","journal-title":"Transl Androl Urol"},{"key":"R3-20260905","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.juro.2015.05.098","article-title":"Peyronie's disease: AUA 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