{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,9,15]],"date-time":"2022-09-15T06:33:29Z","timestamp":1663223609157},"reference-count":13,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2022,9,14]],"date-time":"2022-09-14T00:00:00Z","timestamp":1663113600000},"content-version":"vor","delay-in-days":1383,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asian J Neurosurg"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:p>\n          Background: The management of unruptured cerebral aneurysms (UCA) in elderly population is a challenge. With a very high life expectancy and high risk of rupture in Japan, the need for identifying the best treatment modality is essential to help the patients in decision-making. Methods: This was a 2-year single-center retrospective comparative analysis of the outcomes of surgical clipping (SC) in patients aged above 75 and &lt;75 years. The modified Rankin score was used to stratify the patients and to analyze the functional outcome. Functional status at discharge was the primary end point. Results: There were 224 patients with 239 aneurysms. About 12.5% of the patients were more than 75 years with a mean age of 77.85. The mean age of patients &lt;75 years was 60.96, and it was statistically significant. The overall male-to-female ratio was 1:3.3. The most common location was the middle cerebral artery followed by internal carotid artery at the posterior communicating and ophthalmic segments, and 22 patients had aneurysms of the posterior circulation. Nearly 77% of the aneurysms were &lt;6 mm. There was no significant difference in size of the aneurysm as the age increased to more than 75 years. There were complications in 6 patients, and there was no mortality in the study population. There was no statistically significant difference in the outcome between the groups. Conclusions: SC can be considered a safe option for UCA in the aging population.<\/jats:p>","DOI":"10.4103\/ajns.ajns_151_17","type":"journal-article","created":{"date-parts":[[2018,4,25]],"date-time":"2018-04-25T12:01:21Z","timestamp":1524657681000},"page":"1108-1111","source":"Crossref","is-referenced-by-count":0,"title":["Does age affects the surgical outcome in patients with unruptured cerebral aneurysms? A 2-year retrospective study from a single center in Japan"],"prefix":"10.1055","volume":"13","author":[{"given":"Shyam","family":"Duvuru","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Banbuntane Hotokukai Hospital, Fujita Health University, Nagoya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Treepob","family":"Sae-Ngow","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Banbuntane Hotokukai Hospital, Fujita Health University, Nagoya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoko","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Banbuntane Hotokukai Hospital, Fujita Health University, Nagoya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsukasa","family":"Kawase","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Banbuntane Hotokukai Hospital, Fujita Health University, Nagoya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiro","family":"Yamada","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Banbuntane Hotokukai Hospital, Fujita Health University, Nagoya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riki","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Banbuntane Hotokukai Hospital, Fujita Health University, Nagoya"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,9,14]]},"reference":[{"key":"key-10.4103\/1793-5482.231006-1","first-page":"485","volume-title":"Factors affecting formation and growth of intracranial aneurysms: A long-term follow-up study","author":"Juvela","year":"2001","journal-title":"Stroke"},{"key":"key-10.4103\/1793-5482.231006-2","first-page":"1155","volume-title":"Long-term follow-up study of unruptured intracranial aneurysms","author":"Yasui","year":"1997","journal-title":"Neurosurgery"},{"key":"key-10.4103\/1793-5482.231006-3","first-page":"2474","volume-title":"The natural course of unruptured cerebral aneurysms in a Japanese cohort","author":"UCAS","year":"2012","journal-title":"N Engl J Med"},{"key":"key-10.4103\/1793-5482.231006-4","first-page":"1320","volume-title":"Effect of age on outcomes of treatment of unruptured cerebral aneurysms: A study of the National Inpatient Sample 2001-2008","author":"Brinjikji","year":"2011","journal-title":"Stroke"},{"key":"key-10.4103\/1793-5482.231006-5","first-page":"2720","volume-title":"International subarachnoid aneurysm trial of neurosurgical clipping versus endovascular coiling: Subgroup analysis of 278 elderly patients","author":"Ryttlefors","year":"2008","journal-title":"Stroke"},{"key":"key-10.4103\/1793-5482.231006-6","first-page":"18","volume-title":"Age-dependent differences in short-term outcome after surgical or endovascular treatment of unruptured intracranial aneurysms in the United States, 1996-2000","author":"Barker","year":"2004","journal-title":"Neurosurgery"},{"key":"key-10.4103\/1793-5482.231006-7","first-page":"253867","volume-title":"Cerebral vasospasm in patients over 80 years treated by coil embolization for ruptured cerebral aneurysms","author":"Hishikawa","year":"2014","journal-title":"Biomed Res Int"},{"key":"key-10.4103\/1793-5482.231006-8","first-page":"59","volume-title":", Morita A, Juvela S, Yonekura M, et al. Development of the PHASES score for prediction of risk of rupture of intracranial aneurysms: A pooled analysis of six prospective cohort studies","author":"Greving","year":"2014","journal-title":"Lancet Neurol"},{"key":"key-10.4103\/1793-5482.231006-9","first-page":"103","volume-title":", Piepgras DG, et al. Unruptured intracranial aneurysms: Natural history, clinical outcome, and risks of surgical and endovascular treatment","author":"Wiebers","year":"2003","journal-title":"Lancet"},{"key":"key-10.4103\/1793-5482.231006-10","first-page":"275","volume-title":"Analysis of subarachnoid hemorrhage according to the Japanese Standard Stroke Registry Study \u2013 Incidence, outcome, and comparison with the International Subarachnoid Aneurysm Trial","author":"Ikawa","year":"2004","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"key-10.4103\/1793-5482.231006-11","first-page":"1349","volume-title":"Long-term follow-up of unruptured intracranial aneurysms repaired in California","author":"Gonda","year":"2014","journal-title":"J Neurosurg"},{"key":"key-10.4103\/1793-5482.231006-12","first-page":"2844","volume-title":"Technological advances in the management of unruptured intracranial aneurysms fail to improve outcome in New York State","author":"Zacharia","year":"2011","journal-title":"Stroke"},{"key":"key-10.4103\/1793-5482.231006-13","first-page":"988","volume-title":"Comparative effectiveness of unruptured cerebral aneurysm therapies: Propensity score analysis of clipping versus coiling","author":"McDonald","year":"2013","journal-title":"Stroke"}],"container-title":["Asian Journal of Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.4103\/ajns.AJNS_151_17.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,15]],"date-time":"2022-09-15T00:02:00Z","timestamp":1663200120000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.4103\/ajns.AJNS_151_17"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12]]},"references-count":13,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2022,9,14]]},"published-print":{"date-parts":[[2018,12]]}},"URL":"https:\/\/doi.org\/10.4103\/ajns.ajns_151_17","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1793-5482","2248-9614"],"issn-type":[{"value":"1793-5482","type":"print"},{"value":"2248-9614","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12]]}}}