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Nucleus accumbens (NAcc) comes out among the other targets in patients with MD and comorbid OCD when physiopathology and limited side effects are taken into account. We report a 27-year-old male with MD and OCD who was treated by bilateral NAcc-DBS. The aim of this study is to discuss NAcc as a DBS target in patients with MD and OCD and to report the first case of a psychiatric disorder treated with DBS in Turkey.<\/jats:p>","DOI":"10.4103\/ajns.ajns_319_16","type":"journal-article","created":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T09:34:29Z","timestamp":1641288869000},"page":"842-844","source":"Crossref","is-referenced-by-count":2,"title":["Major depression and obsessive-compulsive disorder treated with deep brain stimulation of bilateral nucleus accumbens: The first case of Turkey"],"prefix":"10.1055","volume":"13","author":[{"given":"Sabri","family":"Ayd\u0131n","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Istanbul Bilim University, Istanbul"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huseyin","family":"Canaz","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Istanbul Bilim University, Istanbul"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bar\u0131s","family":"Topcular","sequence":"additional","affiliation":[{"name":"Department of Neurology, Istanbul Bilim University, Istanbul"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zuzana","family":"Benackova","sequence":"additional","affiliation":[{"name":"Clinic of Psychiatry, Kosice"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,9,14]]},"reference":[{"key":"key-10.4103\/1793-5482.238051-1","doi-asserted-by":"crossref","first-page":"e675","DOI":"10.1038\/tp.2015.171","article-title":"Effects of deep brain stimulation on prepulse inhibition in obsessive-compulsive disorder","author":"Kohl","year":"2015","journal-title":"Transl Psychiatry"},{"key":"key-10.4103\/1793-5482.238051-2","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1176\/ajp.2006.163.11.1905","article-title":"Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: A STAR*D report","author":"Rush","year":"2006","journal-title":"Am J Psychiatry"},{"key":"key-10.4103\/1793-5482.238051-3","doi-asserted-by":"crossref","unstructured":"Bewernick B, Schlaepfer TE. 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