{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T02:38:52Z","timestamp":1792291132327,"version":"4.4.0"},"reference-count":30,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2022,9,14]],"date-time":"2022-09-14T00:00:00Z","timestamp":1663113600000},"content-version":"vor","delay-in-days":1474,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asian J Neurosurg"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:p>\n          Background: Nonmissile anterior skull-base penetrating brain injuries (NASBPBIs) have specific characteristic features that are different from missile injuries. Our study presents our experiences on the characteristic features as well as management of NASBPBI. Materials and Methods: We retrospectively reviewed 22 consecutive patients with NASBPBI managed at our institute during a 13-year period. The mechanism of injury, clinical investigations, and complications were analyzed, with more emphasis on diagnostic and treatment regimen. Results: The 22 cases included in our study comprise of 20 males and 2 females. Majority (72.7%) of the patients were adults with a mean age of 27.5 years. The mechanisms of injury often include accidental fall, either onto a small-diameter sharp object (10 cases) or while carrying such an object in the hand (4 cases). The other common mechanisms were stabbing, accident, or during an altercation (8 cases). Clinical manifestations included periorbital hematoma (10 cases, 45.5%) and cerebrospinal fluid rhinorrhea or orbitorrhea (4 cases, 18.2%) as well as signs of embedded foreign object (8 cases, 36.4%). We performed emergency craniotomy in 21 cases and skin debridement in one case. Postoperative complications were abscess (1 case), epilepsy (1 case), and traumatic carotid-cavernous fistula (1 case). Conclusion: Nonmissile injuries are generally on the rise and therefore deserve more attention. We observed that clinical outcomes were excellent in 14 (Glasgow Outcome Scale [GOS] score of 5) and good in the remaining 8 patients (GOS of 4) during 6-month\u201310-year (mean 4.6 years) follow-ups.<\/jats:p>","DOI":"10.4103\/ajns.ajns_36_18","type":"journal-article","created":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T09:34:29Z","timestamp":1641288869000},"page":"742-748","source":"Crossref","is-referenced-by-count":6,"title":["Nonmissile anterior skull-base penetrating brain injury: Experience with 22 patients"],"prefix":"10.1055","volume":"13","author":[{"given":"Zhigang","family":"Lan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seidu","family":"Richard","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan"},{"name":"Department of Immunology, Jiangsu University, Zhenjiang, Jiangsu, China"},{"name":"Department of Surgery, Volta Regional Hospital, Ho, Ghana-West Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaohua","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,9,14]]},"reference":[{"key":"key-10.4103\/1793-5482.238070-1","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.survophthal.2006.06.008","article-title":"Patterns of transorbital intracranial injury: A review and comparison of occult and non-occult cases","author":"Turbin","year":"2006","journal-title":"Surv Ophthalmol"},{"key":"key-10.4103\/1793-5482.238070-2","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1055\/s-0031-1275257","article-title":"Management of nonmissile penetrating brain injuries: A description of three cases and review of the literature","author":"Sweeney","year":"2011","journal-title":"Skull Base Rep"},{"key":"key-10.4103\/1793-5482.238070-3","doi-asserted-by":"crossref","unstructured":"Li XS, Yan J, Liu C, Luo Y, Liao XS, Yu L, et al. 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