{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T10:32:45Z","timestamp":1787653965692,"version":"build-2736575974"},"reference-count":12,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T00:00:00Z","timestamp":1663632000000},"content-version":"vor","delay-in-days":1754,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asian J Neurosurg"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:p>Objectives: Carpal tunnel release surgery has excellent results. The aim of this study was to identify which baseline clinical and demographic factors could predict a good outcome from surgery. Understanding the impact of prognostic factors will enable surgeons to indicate surgical intervention better, provide appropriate preoperative counseling, and manage expectations postoperatively. Materials and Methods: A prospective, observational study included 620 carpal tunnel syndrome patients (age 42.38 \u00b1 11.18 years; mean \u00b1 standard deviation). After the diagnosis had been confirmed by electrodiagnostic studies, patients underwent open carpal tunnel release surgery. Patients were evaluated initially after 2 weeks and eventually after 6 months. Surgical outcome was compared with presurgical findings. Results: Response to surgery was good in 89.4% and 94.2% after 2 weeks and 6 months, respectively. Factors correlated significantly with unfavorable outcome of surgery included old age, longer duration of symptoms, negative Phalen's test, abnormal two-point discrimination test, and weakness of abductor pollicis brevis muscle. Gender, retrograde radiation, and nocturnal symptoms did not correlate with surgical outcome. Conclusion: Elderly patients with longstanding disease, neurological deficits, and negative Phalen's test may not respond to surgery as others. This should be kept in mind in preoperative counseling and postoperative expectations.<\/jats:p>","DOI":"10.4103\/ajns.ajns_3_15","type":"journal-article","created":{"date-parts":[[2017,10,3]],"date-time":"2017-10-03T12:54:35Z","timestamp":1507035275000},"page":"670-673","source":"Crossref","is-referenced-by-count":11,"title":["Factors correlated with unfavorable outcome after carpal tunnel release surgery"],"prefix":"10.1055","volume":"12","author":[{"given":"Fakhr","family":"Fakhouri","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Neurosurgery, Aleppo University Hospital, Aleppo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rana","family":"Alsukhni","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Neurosurgery, Aleppo University Hospital, Aleppo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bashar","family":"Altunbi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Neurosurgery, Aleppo University Hospital, Aleppo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zakaria","family":"Hawoot","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Neurosurgery, Aleppo University Hospital, Aleppo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasha","family":"Dabbagh","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Aleppo University Hospital, Aleppo"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,9,20]]},"reference":[{"key":"key-10.4103\/1793-5482.215772-1","first-page":"1807","volume-title":"Clinical practice.Carpal tunnel syndrome","author":"Katz","year":"2002","journal-title":"N Engl J Med"},{"key":"key-10.4103\/1793-5482.215772-2","first-page":"1674","volume-title":"Clinical surveillance of carpal tunnel syndrome in two areas of the United Kingdom, 1991-2001","author":"Bland","year":"2003","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"key-10.4103\/1793-5482.215772-3","first-page":"78","volume-title":"Carpal tunnel syndrome in older adults","author":"Blumenthal","year":"2006","journal-title":"Muscle Nerve"},{"key":"key-10.4103\/1793-5482.215772-4","first-page":"343","volume-title":"Carpal tunnel syndrome","author":"Bland","year":"2007","journal-title":"BMJ"},{"key":"key-10.4103\/1793-5482.215772-5","first-page":"35","volume-title":"Clinical course, costs and predictive factors for response to treatment in carpal tunnel syndrome: The PALMS study protocol","author":"Jerosch-Herold","year":"2014","journal-title":"BMC Musculoskelet Disord"},{"key":"key-10.4103\/1793-5482.215772-6","first-page":"685","volume-title":"Carpal tunnel surgery: Patient preferences and predictors for satisfaction","author":"Shifflett","year":"2012","journal-title":"Patient Prefer Adherence"},{"key":"key-10.4103\/1793-5482.215772-7","unstructured":"National Research Council. Networking Health: Prescriptions for the Internet. Washington, D.C.: National Academy Press; 2000."},{"key":"key-10.4103\/1793-5482.215772-8","first-page":"857","volume-title":"Impoverished diabetic patients whose doctors facilitate their participation in medical decision making are more satisfied with their care","author":"Golin","year":"2002","journal-title":"J Gen Intern Med"},{"key":"key-10.4103\/1793-5482.215772-9","first-page":"303","volume-title":"Patient satisfaction after open carpal tunnel release correlates with depression","author":"Lozano","year":"2008","journal-title":"J Hand Surg Am"},{"key":"key-10.4103\/1793-5482.215772-10","first-page":"599","volume-title":"The effect of age and gender upon symptoms and surgical outcomes in carpal tunnel syndrome","author":"Hobby","year":"2005","journal-title":"J Hand Surg Br"},{"key":"key-10.4103\/1793-5482.215772-11","first-page":"1184","volume-title":"Predictors of outcomes of carpal tunnel release","author":"Katz","year":"2001","journal-title":"Arthritis Rheum"},{"key":"key-10.4103\/1793-5482.215772-12","first-page":"660","volume-title":"Age is an important predictor of short-term outcome in endoscopic carpal tunnel release","author":"Hansen","year":"2009","journal-title":"J Hand Surg Eur Vol"}],"container-title":["Asian Journal of Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.4103\/ajns.AJNS_3_15.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T22:53:52Z","timestamp":1663714432000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.4103\/ajns.AJNS_3_15"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12]]},"references-count":12,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2022,9,20]]},"published-print":{"date-parts":[[2017,12]]}},"URL":"https:\/\/doi.org\/10.4103\/ajns.ajns_3_15","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1793-5482","2248-9614"],"issn-type":[{"value":"1793-5482","type":"print"},{"value":"2248-9614","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12]]}}}