{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T08:52:49Z","timestamp":1783155169487,"version":"3.54.6"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2022,8,16]],"date-time":"2022-08-16T00:00:00Z","timestamp":1660608000000},"content-version":"vor","delay-in-days":349,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asian J Neurosurg"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:p>\n          Background: Mesial temporal lobe epilepsy attributed to low-grade glioma is known for intractable seizures and choice of surgery range from lesionectomy (Lo) to lesionectomy with anteromesial temporal resection (L0 + AMTR) is still debatable. We intend to analyze the seizure outcome after lesionectomy alone or with AMTR. Subjects and Methods: Retrospective analyses of patients operated for medial low-grade temporal lobe tumors with seizures were included in the study. Preoperative records include video-electroencephalographic, magnetic resonance imaging (epilepsy protocol), and neuropsychological evaluation for language, memory, and dominance were assessed. Two groups (Lo [Group I] and Lo + AMTR [Group II]) were assessed after surgery by the international league against epilepsy (ILAE) seizure outcome scale. Results: A total of 39 patients underwent Lo (n = 20) and Lo + AMTR (n = 19) with a mean age of 26.92 \u00b1 12.96 months, and mean duration of seizures was 36.87 46.76 months. A total of 23 patients had long-term intractable seizures for &gt;1 year despite &gt;2 drugs(Group I [n = 10], Group II [n = 13]); remaining 16 had frequent seizures of &lt;1-year duration. In the postoperative period, on a mean follow-up of 49.72 \u00b1 34.10 months, the ILAE outcome scale shown a significant difference (P = 0.05) in seizure outcome between two groups. Four (40%) patients out of 10 having refractory seizures in Group I and 8 (80%) from the Group II out of 10 patients could achieved ILAE Class 1 outcome after surgery. Histopathology analysis includes low-grade astrocytoma (n = 29) and in two patients there were associated CA1 neuronal loss in hippocampus, one patient had mesial temporal sclerosis from Group II attributed to its intractability in seizures. Conclusion: For the mesial temporal low-grade glioma presenting with seizures, the seizure outcome by lesionectomy with AMTR is superior than lesionectomy only.<\/jats:p>","DOI":"10.4103\/ajns.ajns_496_20","type":"journal-article","created":{"date-parts":[[2021,9,19]],"date-time":"2021-09-19T12:55:31Z","timestamp":1632056131000},"page":"518-524","source":"Crossref","is-referenced-by-count":3,"title":["Seizure outcome after lesionectomy with or without concomitant anteromedial temporal lobectomy for low-grade gliomas of the medial temporal lobe"],"prefix":"10.1055","volume":"16","author":[{"given":"Vandan","family":"Raiyani","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suyash","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, All India Institute of Medical Sciences, Raebarelly, Uttar Pradesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayesh","family":"Sardhara","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anant","family":"Mehrotra","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinita","family":"Mani","sequence":"additional","affiliation":[{"name":"Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vimal","family":"Paliwal","sequence":"additional","affiliation":[{"name":"Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lily","family":"Pal","sequence":"additional","affiliation":[{"name":"Department of Pathology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashutosh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priyadarshi","family":"Dikshit","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ved","family":"Maurya","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawan","family":"Verma","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay","family":"Behari","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,8,16]]},"container-title":["Asian Journal of Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.4103\/ajns.AJNS_496_20.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,16]],"date-time":"2022-08-16T22:40:02Z","timestamp":1660689602000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.4103\/ajns.AJNS_496_20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":0,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2022,8,16]]},"published-print":{"date-parts":[[2021,9]]}},"URL":"https:\/\/doi.org\/10.4103\/ajns.ajns_496_20","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1793-5482","2248-9614"],"issn-type":[{"value":"1793-5482","type":"print"},{"value":"2248-9614","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9]]}}}