{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T01:44:20Z","timestamp":1782956660489,"version":"3.54.5"},"reference-count":22,"publisher":null,"issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>This systematic review and meta-analysis aimed to investigate the current evidence on the efficacy of tympanostomy and adenoidectomy in children with otitis media with effusion in comparison with tympanostomy alone following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>We completed a comprehensive search of PubMed, Web of Science, Scopus and Cochrane Library databases for relevant studies published in the literature with no date restrictions. We collected the results of the databases search and removed duplicated studies by Rayyan QCRI and EndNote Software X8. We used an Excel sheet for screening titles and abstracts, full text and data extraction. For quality assessment, we used Cochrane Handbook of Systematic Reviews of Interventions 5.1.0 using the quality assessment table provided in Part 2 and Chapter 8.5, and quantitative data synthesis was done using Review Manager (RevMan) software version 5.4.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The literature search showed 1510 studies, of which five studies were included in data synthesis. The study measured the effect through number of acute otitis media (AOM) episodes, cumulative number of AOM episodes, siblings with Otitis media (OM), hearing level hearing loss scale of the left, and right ears. The pooled effect estimates showed significant difference between tympanostomy with adenoidectomy versus tympanostomy alone in hearing level hearing loss scale of both ears (SMD -0.17, 95% CI [-0.29, -0.05],\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      -value=0.005). However, the pooled results were not heterogeneous (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.25,\n                      <jats:italic toggle=\"yes\">I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      = 24%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Tympanostomy with adenoidectomy improves hearing compared to tympanostomy alone, but both treatments have similar effects on ear infection rates. Further research with larger samples is needed to confirm these findings and assess long-term benefits.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ajps.ajps_144_22","type":"journal-article","created":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T07:19:38Z","timestamp":1725952778000},"page":"236-241","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Efficacy of Adenoidectomy versus Tympanostomy on the Otitis Media with Effusion: A Systematic Review and Meta-Analysis"],"prefix":"10.67481","volume":"21","author":[{"given":"Abdullah A.","family":"Alamri","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, King Abdulaziz University Hospital, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hosam A.","family":"Amoodi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, Jeddah University, Jeddah, Saudi Arabia"},{"name":"Department of Otolaryngology, Head and Neck Surgery, Fakeeh Hospital, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahad A.","family":"Alsubaie","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine in Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Areej A.","family":"Alsehly","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine in Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Razan O.","family":"Alshuaibi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine in Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leena A.","family":"Alotaibi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine in Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahar J.","family":"Almaghrabi","sequence":"additional","affiliation":[{"name":"College of Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah F.","family":"Mozahim","sequence":"additional","affiliation":[{"name":"College of Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naif F.","family":"Mozahim","sequence":"additional","affiliation":[{"name":"College of Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albaraa","family":"Tonkal","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, King Abdulaziz University Hospital, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":null,"published-online":{"date-parts":[[2024,9,7]]},"reference":[{"key":"R1-20240921","first-page":"459","article-title":"Epidemiology and natural history of secretory otitis","volume":"5","author":"Tos","year":"1984","journal-title":"Am J Otol"},{"key":"R2-20240921","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1097\/00005537-200310000-00004","article-title":"Natural history of untreated otitis media","volume":"113","author":"Rosenfeld","year":"2003","journal-title":"Laryngoscope"},{"key":"R3-20240921","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1056\/NEJM198712033172305","article-title":"Effectiveness of adenoidectomy and tympanostomy tubes 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