{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T01:44:18Z","timestamp":1782956658124,"version":"3.54.5"},"reference-count":17,"publisher":null,"issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>To predict native liver survival (NLS) after Kasai portoenterostomy (KP) for biliary atresia (BA) using pre-operative clinical data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Pre-operative data were collected from 29 patients with BA who underwent KP at our department between 1989 and 2017 and were analysed including serum albumin, bilirubin, prothrombin time-international normalised ratio, body height, body weight, age at KP, paediatric end-stage liver disease score calculated using the pre-operative data and the period of NLS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The 10-year NLS rate of all patients was 51%. A multivariate analysis revealed that among all factors, the pre-KP serum albumin level was the only independent predictor of NLS (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.04, hazard ratio = 0.269, 95% confidence interval = 0.077\u20130.934). The area under the receiver operating characteristic curve for NLS, determined using pre-KP serum albumin was 0.760 and 3.75 mg\/dl was selected as the cut-off value. There was a significant difference in NLS between patients with high (\u22653.8 mg\/dl) and low (\u22643.7 mg\/dl) pre-KP serum albumin (90.0% vs. 31.5%,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Decreased pre-KP serum albumin may reflect not only functional impairment of the liver, but also the inflammatory process, which is hypothesized to occur during its advancement. The pre-KP serum albumin level may be a good prognostic factor for NLS in post-KP BA patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ajps.ajps_158_22","type":"journal-article","created":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T08:00:23Z","timestamp":1709280023000},"page":"232-235","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Pre-operative Serum Albumin Predicts Native Liver Survival in Biliary Atresia"],"prefix":"10.67481","volume":"21","author":[{"given":"Kakeru","family":"Machino","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery, Fukushima Medical University Hospital, Fukushima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kotaro","family":"Mimori","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Fukushima Medical University Hospital, Fukushima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seiya","family":"Ogata","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Fukushima Medical University Hospital, Fukushima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yosuke","family":"Minami","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Fukushima Medical University Hospital, Fukushima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirofumi","family":"Shimizu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Fukushima Medical University Hospital, Fukushima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michitoshi","family":"Yamashita","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Fukushima Medical University Hospital, Fukushima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Fukushima Medical University Hospital, Fukushima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":null,"published-online":{"date-parts":[[2024,3,1]]},"reference":[{"key":"R1-20240921","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1016\/S0140-6736(09)60946-6","article-title":"Biliary atresia","volume":"374","author":"Hartley","year":"2009","journal-title":"Lancet"},{"key":"R2-20240921","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1007\/s11894-017-0555-z","article-title":"Early and peri-operative prognostic indicators in infants undergoing hepatic portoenterostomy for biliary atresia:A review","volume":"19","author":"Lopez","year":"2017","journal-title":"Curr Gastroenterol Rep"},{"key":"R3-20240921","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1097\/00007890-200207270-00006","article-title":"Development of a pediatric end-stage liver disease score to predict poor outcome in children awaiting liver transplantation","volume":"74","author":"McDiarmid","year":"2002","journal-title":"Transplantation"},{"key":"R5-20240921","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1097\/MPG.0b013e318282a913","article-title":"International incidence and outcomes of biliary atresia","volume":"56","author":"Jimenez-Rivera","year":"2013","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"R6-20240921","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/0022-3468(68)90897-X","article-title":"Surgical treatment of biliary atresia","volume":"3","author":"Kasai","year":"1968","journal-title":"J Pediatr Surg"},{"key":"R7-20240921","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1007\/BF01556048","article-title":"Technique and results of operative management of biliary atresia","volume":"2","author":"Kasai","year":"1978","journal-title":"World J Surg"},{"key":"R8-20240921","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1007\/s00383-017-4173-5","article-title":"Liver transplantation for biliary atresia:A systematic review","volume":"33","author":"Kasahara","year":"2017","journal-title":"Pediatr Surg Int"},{"key":"R9-20240921","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1620\/tjem.115.345","article-title":"An attempt to determine surgical indication for biliary atresia by laboratory examination","volume":"115","author":"Chiba","year":"1975","journal-title":"Tohoku J Exp Med"},{"key":"R10-20240921","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1007\/s00383-018-4231-7","article-title":"Clinical and pathological features of patients with biliary atresia who survived for more than 5 years with native liver","volume":"34","author":"Sun","year":"2018","journal-title":"Pediatr Surg Int"},{"key":"R11-20240921","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/S0022-3468(97)90173-1","article-title":"Biliary atresia:Should all patients undergo a portoenterostomy?","volume":"32","author":"Azarow","year":"1997","journal-title":"J Pediatr Surg"},{"key":"R12-20240921","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1007\/s00383-012-3060-3","article-title":"PELD score and age as a prognostic index of biliary atresia patients undergoing Kasai portoenterostomy","volume":"28","author":"Rhu","year":"2012","journal-title":"Pediatr Surg Int"},{"key":"R13-20240921","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1097\/MPG.0000000000001289","article-title":"Early posthepatoportoenterostomy predictors of native liver survival in biliary atresia","volume":"64","author":"Nightingale","year":"2017","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"R14-20240921","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1002\/jpen.1451","article-title":"Hypoalbuminemia:Pathogenesis and clinical significance","volume":"43","author":"Soeters","year":"2019","journal-title":"JPEN J Parenter Enteral Nutr"},{"key":"R15-20240921","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1002\/lt.24796","article-title":"Living donor liver transplantation for post-Kasai biliary atresia:Analysis of pretransplant predictors of outcomes in infants","volume":"23","author":"Kitajima","year":"2017","journal-title":"Liver Transpl"},{"key":"R16-20240921","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1097\/00007890-200505150-00060","article-title":"PELD score and posttransplant outcome in pediatric liver transplantation:A retrospective study of 100 recipients","volume":"79","author":"Bourdeaux","year":"2005","journal-title":"Transplantation"},{"key":"R17-20240921","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.jpeds.2005.04.073","article-title":"Biliary atresia:Clinical profiles, risk factors, and outcomes of 755 patients listed for liver transplantation","volume":"147","author":"Utterson","year":"2005","journal-title":"J Pediatr"},{"key":"R18-20240921","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1016\/j.jpedsurg.2008.04.012","article-title":"Timing of liver transplantation in biliary atresia-results in 71 children managed by a multidisciplinary team","volume":"43","author":"Cowles","year":"2008","journal-title":"J Pediatr Surg"}],"container-title":["African Journal of Paediatric Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.4103\/ajps.ajps_158_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:49:42Z","timestamp":1782953382000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.4103\/ajps.ajps_158_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,1]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/ajps.ajps_158_22","relation":{},"ISSN":["0189-6725","0974-5998"],"issn-type":[{"value":"0189-6725","type":"print"},{"value":"0974-5998","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,1]]},"assertion":[{"value":"2022-11-26","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-03","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}