{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T01:44:24Z","timestamp":1782956664325,"version":"3.54.5"},"reference-count":15,"publisher":null,"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,1,4]]},"abstract":"\n Introduction:<\/jats:title>\n Despite all the advances, the mortality rate of congenital diaphragmatic hernia (CDH) ranges from 30% to 60% for isolated CDH and as high as 89% when they are associated with additional structural or chromosomal anomalies. Hence, a study was conducted to evaluate the factors contributing to the mortality of neonates treated for CDH or the eventration of diaphragm.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n A retrospective study was conducted in the department of paediatric surgery at a tertiary centre. The neonates admitted with a diagnosis of CDH or eventration requiring surgery, between March 2013 and March 2021, were included in the study.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n A total of 123 neonates were included in the study. The variables, earlier median age at presentation (1 [1\u201323] vs. 3 [1\u201328];\n P<\/jats:italic>\n < 0.001; Mann\u2013Whitney U-test), preterm birth (10\/79 vs. 0\/44;\n P<\/jats:italic>\n = 0.01; Fischer\u2019s exact test), inborn (68\/79 vs. 27\/44;\n P<\/jats:italic>\n = 0.002; Chi-square test), weight \u22642 kg (18\/79 vs. 1\/44;\n P<\/jats:italic>\n = 0.003; Chi-square test), central cyanosis at presentation (21\/79 vs. 1\/44;\n P<\/jats:italic>\n < 0.001; Chi-square test), antenatal detection (47\/79 vs. 14\/44;\n P<\/jats:italic>\n = 0.003; Chi-square test) and earlier mean age at surgery (3.66 \u00b1 1.47 vs. 7.66 \u00b1 6.88;\n P<\/jats:italic>\n < 0.001; Independent sample\n t<\/jats:italic>\n -test) were associated with increased mortality. On multinominal logistic regression analysis, the factors preterm (odd\u2019s Ratio [OR] =4.735;\n P<\/jats:italic>\n = 0.03), weight \u22642 kg (OR = 5.081;\n P<\/jats:italic>\n = 0.02), central cyanosis at presentation (OR = 6.969;\n P<\/jats:italic>\n = 0.008) and antenatal detection (OR = 7.471;\n P<\/jats:italic>\n = 0.006) were found to be independently associated with increased mortality in CDH\/eventration.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n The factors: prematurity, weight <2 kg, cyanosis at presentation and antenatal diagnosis were independently associated with increased mortality in neonates with CDH\/eventration requiring surgery.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ajps.ajps_165_21","type":"journal-article","created":{"date-parts":[[2023,1,4]],"date-time":"2023-01-04T08:04:31Z","timestamp":1672819471000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Factors Contributing to Mortality in Neonates with Congenital Diaphragmatic Hernia and Eventration"],"prefix":"10.67481","author":[{"given":"Raghunath Bangalore","family":"Vasudev","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nitin","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bahubali Deepak","family":"Gadgade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veerabhadra","family":"Radhakrishna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamatha","family":"Basavaraju","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alladi","family":"Anand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":null,"reference":[{"key":"key-10.4103\/0189-6725.367105-1","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1053\/j.sempedsurg.2014.09.008","article-title":"Congenital diaphragmatic hernia: Where and what is the evidence?","author":"Losty","year":"2014","journal-title":"Semin Pediatr Surg"},{"key":"key-10.4103\/0189-6725.367105-2","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s00383-019-04442-z","article-title":"Congenital diaphragmatic 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