{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T17:13:10Z","timestamp":1793293990521,"version":"4.5.0"},"reference-count":18,"publisher":null,"issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:sec>\n                    <jats:title>Context:<\/jats:title>\n                    <jats:p>Gastroschisis is a common abdominal wall defect faced by paediatric surgeons worldwide. Early gastroschisis detection, access to improved neonatal intensive care, parenteral nutrition and surgical techniques have led to a reported improvement in mortality of between 4% and 8% in high-income countries. In low to middle income countries, such as in Southern Africa, however, there is as much as 84% mortality among patients with gastroschisis. This is thought to be due to factors such as lack of antenatal screening, access to neonatal intensive care services and parenteral nutrition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>The purpose of this study was to calculate the prevalence of gastroschisis and report on its neonatal mortality in the Eastern Cape Province of South Africa.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Settings and Design:<\/jats:title>\n                    <jats:p>A retrospective observational study on all neonates with gastroschisis, presenting to a tertiary facility offering paediatric surgical services within the Eastern Cape Province from 1 January 2016 to 31 December 2018.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects and Methods:<\/jats:title>\n                    <jats:p>A convenience sampling method was used in retrieving patient files for the study period. Statistical analysis used: Stata version 13.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Thirty-seven neonates were included in the study. The prevalence of gastroschisis ranged from 0.07% to 0.18% throughout the 3-year study. The majority (81%) of the neonates were outborn and delivered by mode of caesarean section. Nearly 60% (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 22) were female. 54% (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 20) of neonates died within the neonatal period.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The majority of the neonates in this study were outborn and female. Although their mortality rate was higher than reported in high-income countries, it was much improved from what is reported in the low to middle income countries.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ajps.ajps_178_21","type":"journal-article","created":{"date-parts":[[2022,12,15]],"date-time":"2022-12-15T10:33:50Z","timestamp":1671100430000},"page":"46-50","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Prevalence of Gastroschisis and its Neonatal Mortality in the Eastern Cape Province tertiary Institutions"],"prefix":"10.67481","volume":"20","author":[{"given":"Sello S.","family":"Machaea","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milind R.","family":"Chitnis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phumza","family":"Nongena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":null,"reference":[{"key":"R1-9-20240829","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.earlhumdev.2014.05.006","article-title":"Frequency of anomalies and hospital outcomes in infants with gastroschisis and omphalocele","volume":"90","author":"Corey","year":"2014","journal-title":"Early Hum Dev"},{"key":"R2-9-20240829","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1053\/jpsu.2001.20004","article-title":"Gastroschisis: A plea for risk categorization","volume":"36","author":"Molik","year":"2001","journal-title":"J Pediatr Surg"},{"key":"R3-9-20240829","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1038\/sj.jp.7211616","article-title":"Gastroschisis in the United States 1988-2003: Analysis and risk categorization of 4344 patients","volume":"27","author":"Abdullah","year":"2007","journal-title":"J Perinatol"},{"key":"R4-9-20240829","first-page":"4","article-title":"Gastroschisis in a developing country: Poor resuscitation is a more significant predictor of mortality than postnasal transfer time","volume":"54","author":"Stevens","year":"2016","journal-title":"S Afr J Surg"},{"key":"R5-9-20240829","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1016\/j.surg.2015.04.037","article-title":"Infant, maternal, and geographic factors influencing gastroschisis related mortality in Zimbabwe","volume":"158","author":"Apfeld","year":"2015","journal-title":"Surgery"},{"key":"R6-9-20240829","first-page":"86","article-title":"Is the incidence of gastroschisis rising in South Africa in accordance with international trends? A retrospective analysis at Pretoria Academic and Kalafong Hospitals, 1981-2001","volume":"42","author":"Arnold","year":"2004","journal-title":"S Afr J Surg"},{"key":"R7-9-20240829","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1097\/AOG.0b013e31829cbbb4","article-title":"Prevalence and correlates of gastroschisis in 15 states, 1995 to 2005","volume":"122","author":"Kirby","year":"2013","journal-title":"Obstet Gynecol"},{"key":"R8-9-20240829","doi-asserted-by":"crossref","first-page":"23","DOI":"10.15585\/mmwr.mm6502a2","article-title":"Increasing prevalence of gastroschisis \u2013 14 states, 1995-2012","volume":"65","author":"Jones","year":"2016","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"R9-9-20240829","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s00383-009-2348-4","article-title":"Gastroschisis: A third world perspective","volume":"25","author":"Sekabira","year":"2009","journal-title":"Pediatr Surg Int"},{"key":"R10-9-20240829","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1016\/j.jpedsurg.2013.07.004","article-title":"Effect of delivery approach on outcomes in fetuses with gastroschisis","volume":"48","author":"Nasr","year":"2013","journal-title":"J Pediatr Surg"},{"key":"R11-9-20240829","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1016\/j.jpedsurg.2016.12.003","article-title":"Improved outcomes for inborn babies with uncomplicated gastroschisis","volume":"52","author":"Dalton","year":"2017","journal-title":"J Pediatr Surg"},{"key":"R12-9-20240829","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1002\/ajmg.c.30175","article-title":"Non-genetic risk factors for gastroschisis","volume":"148C","author":"Rasmussen","year":"2008","journal-title":"Am J Med Genet C Semin Med Genet"},{"key":"R13-9-20240829","doi-asserted-by":"crossref","first-page":"75","DOI":"10.3402\/ijch.v68i1.18297","article-title":"The incidence and maternal age distribution of abdominal wall defects in Norway and Arkhangelskaja Oblast in Russia","volume":"68","author":"Jelena","year":"2009","journal-title":"Int J Circumpolar Health"},{"key":"R14-9-20240829","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.jpedsurg.2004.11.037","article-title":"Perinatal management of gastroschisis: Analysis of a newly established clinical pathway","volume":"40","author":"Vegunta","year":"2005","journal-title":"J Pediatr Surg"},{"key":"R15-9-20240829","doi-asserted-by":"crossref","first-page":"F355","DOI":"10.1136\/archdischild-2016-312394","article-title":"Mode of delivery and outcomes of infants with gastroschisis: A meta-analysis of observational studies","volume":"103","author":"Kirollos","year":"2018","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"R16-9-20240829","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1016\/j.jpedsurg.2007.12.030","article-title":"Gastroschisis closure \u2013 Does method really matter?","volume":"43","author":"Weinsheimer","year":"2008","journal-title":"J Pediatr Surg"},{"key":"R17-9-20240829","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/s00383-020-04772-3","article-title":"Failure of primary closure predicts prolonged length of stay in gastroschisis patients","volume":"37","author":"Lin","year":"2021","journal-title":"Pediatr Surg Int"},{"key":"R18-9-20240829","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1007\/s00383-018-4282-9","article-title":"The factors associated with successful early enteral feeding in gastroschisis","volume":"34","author":"Pratheeppanyapat","year":"2018","journal-title":"Pediatr Surg Int"}],"container-title":["African Journal of Paediatric Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.4103\/ajps.ajps_178_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:49:24Z","timestamp":1782953364000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.4103\/ajps.ajps_178_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/ajps.ajps_178_21","relation":{},"ISSN":["0189-6725"],"issn-type":[{"value":"0189-6725","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]}}}