{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T05:36:56Z","timestamp":1791005816426,"version":"4.1.0"},"reference-count":18,"publisher":null,"issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Esophageal atresia (EA) is a rare congenital malformation. A high incidence of GER unresponsive to medical management is noted with EA. Literature suggests that complications from GER can persist in adulthood. In paediatric age, laparoscopic treatment is a valid option even if recurrence rate is not negligible.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims and Objectives:<\/jats:title>\n                    <jats:p>To evaluate our experience with gastro-esophageal reflux (GER) treatment after esophageal atresia (EA) repair.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>We retrospectively analysed 29 consecutive patients treated for EA at birth and studied for GER at our Institute in a period of 11 years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>24\/29 (82,7%) cases had symptoms of reflux, 17\/29 (58,6%) cases were treated with laparoscopic fundoplication (LF). Three infants were younger than 6 months and had apparent life threatening events (ALTE) condition as principal indication for surgery. No intra-operative complications occurred. 3\/17 LF had open surgical conversion due to technical problems. 2\/17 cases required a second operation. At the last follow-up: (1) 6\/17 (35,3%) of patients healed after the last operation, (2) 8\/17 (47,1%) have GER improvement (four still in medical treatment), (3)2\/17 (11,8%) have persistent GER, (4)1\/17 (5,9%) died for causes not related to antireflux surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>According to literature and to our retrospective analysis, LF for GER after EA repair is feasible, even if recurrence risk is not negligible. Infants less than 6 months old with associated conditions (malformations, gastrostomy\/jejunostomy) seem to have a higher failure rate with a greater risk of conversion. Longer follow-up and multicenter experiences would guarantee an adequate surveillance for patients with EA.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ajps.ajps_25_21","type":"journal-article","created":{"date-parts":[[2022,6,23]],"date-time":"2022-06-23T11:18:01Z","timestamp":1655983081000},"page":"149-152","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Laparoscopic Fundoplication after Oesophageal Atresia 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