{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T01:44:18Z","timestamp":1782956658074,"version":"3.54.5"},"reference-count":19,"publisher":null,"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"Abstract<\/jats:title>\n \n Introduction:<\/jats:title>\n Posterior fossa tumors are significant in pediatric neurooncological populations due to their frequency and morbimortality. We convey a 10-year experience managing pediatric posterior fossa tumors at two reference centers in Cameroon.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n We conducted a cross-sectional study with data collected retrospectively in the Neurosurgery Department of the Central and General Hospitals of Yaounde from January 2010 to December 2019. Included in the study were all patients aged 0\u201315 years who underwent surgery for posterior fossa tumors.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n We retained 43 pediatric posterior fossa tumor files, representing 47.89% of pediatric brain tumors. The male\/female sex ratio was 0.86, with a mean age of 6.93 \u00b1 4.345 years. The predominant clinical presentations were headaches + vomiting (97.7%), visual impairment (67.4%), and altered consciousness (14%). The vermis was the most frequent site affected (46.5%). Hydrocephalus was found to be associated with the tumor in 30 patients (69.8%). Tumor excision was total in 90.7% of cases, with cerebrospinal fluid diversion performed within the surgery in 83% of cases. Pilocytic astrocytomas represented 37.2%, medulloblastomas 30.25%, ependymomas 6.9%, and brainstem gliomas 4.6%. The postoperatory mortality rate was 20.9%. The survival rate at 5 years for medulloblastomas was 43%.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Pediatric posterior fossa tumors are frequent. Pilocytic astrocytomas are the most common histologic type, followed by medulloblastomas. Radical surgery is the leading standard of care. Adjuvant treatment remains limited.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ajps.ajps_37_23","type":"journal-article","created":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T11:00:43Z","timestamp":1727175643000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Clinical, Histologic, and Therapeutic Pattern of Posterior Fossa Tumors in Children in Cameroon: A Cross-sectional Study"],"prefix":"10.67481","author":[{"given":"Bello","family":"Figuim","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Faculty of Medicine and Biomedical Sciences, Yaounde Central Hospital, University of Yaounde I, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oumarou Haman","family":"Nassourou","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Faculty of Medicine and Biomedical Sciences, Yaounde General Hospital, University of Yaounde I, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ndouh Roland","family":"Nchufor","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Health Sciences, Bamenda Regional Hospital, University of Bamenda, Bamenda, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ewane Khadije Gael","family":"Nicaise","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Yaounde General Hospital, Yaound\u00e9, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ndome Toto","family":"Orlane","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Faculty of Medicine and Pharmaceutical Sciences, Douala General Hospital, University of Douala, Douala, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Djientcheu Vincent","family":"de Paul","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Faculty of Medicine and Biomedical Sciences, Yaounde General Hospital, University of Yaounde I, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":null,"published-online":{"date-parts":[[2024,9,18]]},"reference":[{"key":"R1-20240924","article-title":"Epidemiologic profil and management of posterior fossa tumors in children under 16 years old. 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Report of 72 cases","volume":"47","author":"Vinchon","year":"2001","journal-title":"Neurochirurgie"},{"key":"R15-20240924","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1001\/archneur.56.4.421","article-title":"Brain tumors in children","volume":"56","author":"Packer","year":"1999","journal-title":"Arch Neurol"},{"key":"R16-20240924","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.ncl.2018.04.009","article-title":"Pediatric brain tumors","volume":"36","author":"Udaka","year":"2018","journal-title":"Neurol Clin"},{"key":"R17-20240924","first-page":"1","article-title":"M\u00e9dulloblastomes","volume":"10","author":"Taillandier","year":"2006","journal-title":"EMC (Paris)"},{"key":"R18-20240924","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/3-540-30258-1_39","article-title":"Hydrocephalus","author":"Arnell","year":"2006","journal-title":"Berlin Pediatric Surgery, Springer Surgery Atlas Series"},{"key":"R19-20240924","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.1007\/s00381-011-1548-0","article-title":"Hydrocephalus in toddlers:The place of shunts in sub-Sahara African countries","volume":"27","author":"Djientcheu Vde","year":"2011","journal-title":"Childs Nerv Syst"},{"key":"R20-20240924","first-page":"39","article-title":"Central nervous system tumours in Cameroon:Histopathology and demography","volume":"18","author":"Eyenga","year":"2008","journal-title":"Sante"},{"key":"R22-20240924","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/S1278-3218(01)00121-4","article-title":"Determination of target volume in pediatric radiotherapy:Application to brain tumors","volume":"5","author":"Habrand","year":"2001","journal-title":"Cancer Radiother"}],"container-title":["African Journal of Paediatric Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.4103\/ajps.ajps_37_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:49:43Z","timestamp":1782953383000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.4103\/ajps.ajps_37_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,18]]},"references-count":19,"URL":"https:\/\/doi.org\/10.4103\/ajps.ajps_37_23","relation":{},"ISSN":["0189-6725","0974-5998"],"issn-type":[{"value":"0189-6725","type":"print"},{"value":"0974-5998","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,18]]},"assertion":[{"value":"2023-03-11","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-31","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}