{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T12:24:09Z","timestamp":1789302249117,"version":"build-2803163510"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T00:00:00Z","timestamp":1683763200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>As is widely known, blood group antigens are found in varying proportions in individuals of different races and geographical places. The aim of this study is to determine and compare the distribution of red blood cell (RBC) phenotypes in blood donors between the major ethnic groups in Peninsular Malaysia, Sabah, and Sarawak based on the Malaysian population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>MATERIALS AND METHODS:<\/jats:title>\n                    <jats:p>A total of 1213 voluntary blood donors were randomly recruited among those who donated in the National Blood Centre and 10 other different blood banks in state hospitals or their mobile blood donation sessions from January 2021 to December 2021. All donors were typed for blood group systems: ABO, Rh, Kidd, Duffy, MNS, and Kell by automated system using the Galileo Neo Analyser.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      The comparison of the prevalence of the RBC phenotypes among the different ethnic groups as analyzed by Fisher\u2019s exact test, showed significant differences (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05) for Rh, Kidd, Duffy, MN, and Ss blood group antigen. The rare phenotypes: CCDEE (RZRZ) was found in three Malay, Jk (a-b-) in one Chinese, and two Murut, and SS in 8 donors.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>The mapping of RBC phenotypes among major ethnic groups in blood donors in Peninsular, Sabah, and Sarawak, Malaysia, can aid in strengthening the database for the Rare Blood Donor Registry based on the Malaysian population. This study\u2019s finding can also be used to expedite the provision of antigen-negative blood for the transfusion of patients with unexpected red cells antibodies. This will improve the quality and effectiveness of transfusion services in Malaysia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ajts.ajts_104_22","type":"journal-article","created":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T12:07:15Z","timestamp":1751371635000},"page":"29-35","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Mapping red blood cell phenotypes in Malaysia: A tool to overcome transfusion challenges for providing phenotype blood"],"prefix":"10.4103","volume":"19","author":[{"given":"Rozi Hanisa","family":"Musa","sequence":"first","affiliation":[{"name":"National Immunohematology Reference Laboratory, National Blood Centre, Jalan Tun Razak, Kuala Lumpur, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nor Hafizah","family":"Ahmad","sequence":"additional","affiliation":[{"name":"National Immunohematology Reference Laboratory, National Blood Centre, Jalan Tun Razak, Kuala Lumpur, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunaseelan","family":"Muniandi","sequence":"additional","affiliation":[{"name":"National Immunohematology Reference Laboratory, National Blood Centre, Jalan Tun Razak, Kuala Lumpur, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nor Nazahah","family":"Mahmud","sequence":"additional","affiliation":[{"name":"National Immunohematology Reference Laboratory, National Blood Centre, Jalan Tun Razak, Kuala Lumpur, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad Arif Che","family":"Ismail","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, Hospital Raja Perempuan Zainab II, Jalan Hospital, Kelantan, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Masrin Md","family":"Zahrin","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, Umum Sarawak Jalan Hospital, Sarawak, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohd Muhaimin","family":"Kambali","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, Hospital Sultanah Zahirah, Terengganu, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nor Amiza Mat","family":"Amin","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, Hospital Melaka, Melaka, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabariah Mohd","family":"Noor","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, Hospital Raja Permaisuri Bainon, Perak, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salman Mohd","family":"Sahid","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, Hospital Tengku Ampuan Afzan, Pahang, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahnaz Irwani","family":"Sabri","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, Hospital Queen Elizabeth Ii, Lorong Bersatu, Off, Jalan Damai, Luyang Commercial Centre, Sabah, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siti Nadiah Abdul","family":"Kadir","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, Hospital Sultanah Bahiyah, Kedah, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng Yen","family":"Soo","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, Hospital Pulau Pinang, Jalan Residensi, Pulau Pinang, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zanariah","family":"Kassim","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, Sultanah Aminah, Jalan, Persiaran Abu Bakar Sultan, Johor, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohd Fahmi","family":"Aziz","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, Hospital Tuanku Jaafar, Jalan Rasah, Bukit Rasah, Negeri Sembilan, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nafishah","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, Hospital Tengku Ampuan Rahimah, Jalan Langat, Selangor, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wan Noor Falah Wan","family":"Yahaya","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, Hospital Tuanku Fauziah, Perlis, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noryati Abu","family":"Amin","sequence":"additional","affiliation":[{"name":"National Immunohematology Reference Laboratory, National Blood Centre, Jalan Tun Razak, Kuala Lumpur, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,5,11]]},"reference":[{"issue":"1","key":"R1-20260422","article-title":"Distribution of ABO and rhesus D blood antigen in morocco","volume":"6","author":"Benahadi","year":"2013","journal-title":"Intern J Biol Anthropol"},{"key":"R2-20260422","first-page":"521","article-title":"Prevalence of Rh, Duffy, Kell, Kidd and MNSs blood group antigens in the Indian blood donor population","volume":"137","author":"Makroo","year":"2013","journal-title":"Indian J Med Res"},{"key":"R3-20260422","doi-asserted-by":"crossref","first-page":"239","DOI":"10.21307\/immunohematology-2019-456","article-title":"Review: American rare donor program","volume":"20","author":"Flickinger","year":"2004","journal-title":"Immunohematology"},{"key":"R4-20260422","doi-asserted-by":"crossref","first-page":"707152","DOI":"10.1155\/2014\/707152","article-title":"Mapping rare erythrocyte phenotypes in morocco: A tool to overcome transfusion challenges","volume":"2014","author":"Benahadi","year":"2014","journal-title":"J Blood Transfus"},{"key":"R5-20260422","doi-asserted-by":"crossref","first-page":"273","DOI":"10.4103\/ijmr.IJMR_1199_18","article-title":"Red cell antigen phenotypes in blood donors and thalassaemia patients for creation of red cell antigen-matched inventory","volume":"152","author":"Kulkarni","year":"2020","journal-title":"Indian J Med Res"},{"key":"R6-20260422","doi-asserted-by":"crossref","first-page":"215454","DOI":"10.1155\/2013\/215454","article-title":"Clinically significant minor blood group antigens amongst North Indian donor population","volume":"2013","author":"Lamba","year":"2013","journal-title":"Adv Hematol"},{"key":"R7-20260422","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/s43042-020-00096-y","article-title":"Extended blood group profiles for Malays, Chinese and Indians in Peninsular Malaysia","volume":"21","author":"Norul Hajar","year":"2020","journal-title":"Egyp J Med Hum Genet"},{"key":"R8-20260422","doi-asserted-by":"crossref","first-page":"3","DOI":"10.4103\/0973-6247.95042","article-title":"Red cell phenotyping of blood from donors at the National blood center of Malaysia","volume":"6","author":"Musa","year":"2012","journal-title":"Asian J Transfus Sci"},{"key":"R9-20260422","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/S0197-2456(97)00074-3","article-title":"PS power and sample size program, available for free on the Internet","volume":"18","author":"Dupont","year":"1997","journal-title":"Control Clin Trial"}],"container-title":["Asian Journal of Transfusion Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ajts.ajts_104_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:39:27Z","timestamp":1787067567000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ajts.ajts_104_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,11]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/ajts.ajts_104_22","relation":{},"ISSN":["0973-6247","1998-3565"],"issn-type":[{"value":"0973-6247","type":"print"},{"value":"1998-3565","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,11]]},"assertion":[{"value":"2022-08-10","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-25","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}