{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:22:28Z","timestamp":1787840548809,"version":"build-2784847793"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T00:00:00Z","timestamp":1699315200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Inherited factor X (FX) deficiency is a rare autosomal recessive bleeding disorder, presenting with various bleeding manifestations ranging from nonspecific bruising to life-threatening intracranial hemorrhage. It is often misdiagnosed as hemorrhagic disease of the newborn. It is characterized by prolonged prothrombin time, as well as activated partial thromboplastin time, and needs FX level assay for definitive diagnosis. Here, we describe a case of a newborn with FX deficiency who presented with frank umbilical stump bleeding.<\/jats:p>","DOI":"10.4103\/ajts.ajts_127_22","type":"journal-article","created":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T01:01:36Z","timestamp":1707267696000},"page":"370-372","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Factor X deficiency: An overlooked cause of bleeding in the newborn"],"prefix":"10.4103","volume":"19","author":[{"given":"Shalini","family":"Verma","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Era\u2019s Lucknow Medical College and Hospital, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shalini","family":"Tripathi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, King George\u2019s Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mala","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, King George\u2019s Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,11,7]]},"reference":[{"key":"R2-20251022","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/2324709619832332","article-title":"Acquired factor X deficiency in patients with primary light chain amyloidosis","volume":"7","author":"Dejhansathit","year":"2019","journal-title":"Journal of Investigative Medicine High Impact Case Reports"},{"key":"R3-20251022","first-page":"1","article-title":"Factor X deficiency in North Pakistan","volume":"16","author":"Anwar","year":"2004","journal-title":"J Ayub Med Coll Abbottabad"},{"key":"R4-20251022","doi-asserted-by":"crossref","first-page":"2","DOI":"10.4172\/2572-4983.1000163","article-title":"A 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follow-up","volume":"26","author":"Corsini","year":"2015","journal-title":"Blood Coagul Fibrinolysis"},{"key":"R8-20251022","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1111\/j.1365-2516.2008.01856.x","article-title":"Diagnosis and treatment of inherited factor X deficiency","volume":"14","author":"Brown","year":"2008","journal-title":"Haemophilia"},{"key":"R9-20251022","first-page":"49","article-title":"Congenital factor X deficiency","volume":"11","author":"Khurram","year":"2007","journal-title":"J Rawalpindi Med Coll JRMC"},{"key":"R10-20251022","first-page":"183","article-title":"Factor X deficiency and hemophilia A:Occurrence of two different coagulation defects in a family","volume":"38","author":"Parmar","year":"2001","journal-title":"Indian Pediatr"},{"key":"R11-20251022","first-page":"65","article-title":"Congenital factor X deficiency-An unusual cause of intracranial hemorrhage","volume":"14","author":"Sriram","year":"2010","journal-title":"Curr Pediatr Res"},{"key":"R12-20251022","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1038\/jp.2011.122","article-title":"Subgaleal hemorrhage in a neonate with factor X deficiency following a non-traumatic cesarean section","volume":"32","author":"Wetzel","year":"2012","journal-title":"J Perinatol"}],"container-title":["Asian Journal of Transfusion Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ajts.ajts_127_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:24:53Z","timestamp":1787837093000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ajts.ajts_127_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,7]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/ajts.ajts_127_22","relation":{},"ISSN":["0973-6247","1998-3565"],"issn-type":[{"value":"0973-6247","type":"print"},{"value":"1998-3565","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,7]]},"assertion":[{"value":"2022-09-28","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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