{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:26:42Z","timestamp":1787776002107,"version":"build-2784847793"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T00:00:00Z","timestamp":1683763200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Donath-Landsteiner (DL) antibodies are immunoglobulins formed in response to a viral, bacterial, or spirochete infection and are capable of inducing paroxysmal cold hemoglobinuria (PCH), an autoimmune hemolytic anemia. In the past, PCH was most commonly associated with syphilitic infections; however, now, it is more frequently seen in children secondary to upper respiratory infections and DL test is the diagnostic test. We report a case of a 4-year-old male presented with a sudden drop in hemoglobin and hematuria with a 2-week history of fever and upper respiratory tract infection who was subsequently diagnosed as PCH with the help of DL Test.<\/jats:p>","DOI":"10.4103\/ajts.ajts_137_22","type":"journal-article","created":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T15:02:08Z","timestamp":1760799728000},"page":"366-369","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Timely diagnosis of a case of Paroxysmal Cold Haemoglobinuria using Donath-Landsteiner test"],"prefix":"10.4103","volume":"19","author":[{"given":"Nisha","family":"Navin","sequence":"first","affiliation":[{"name":"Department of Haematology, Laboratory Medicine, Al Jalila Children\u2019s Hospital, Dubai, United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rubina","family":"Lone","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, Laboratory Medicine, Al Jalila Children\u2019s Hospital, Dubai, United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,5,11]]},"reference":[{"key":"R1-20251022","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.autrev.2013.11.010","article-title":"Diagnosis and classification of autoimmune hemolytic anemia","volume":"13","author":"Bass","year":"2014","journal-title":"Autoimmun Rev"},{"key":"R2-20251022","doi-asserted-by":"crossref","first-page":"109","DOI":"10.21307\/immunohematology-2019-673","article-title":"Paroxysmal cold hemoglobinuria and the elusive Donath-Landsteiner 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