{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:19:17Z","timestamp":1787775557254,"version":"build-2784847793"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Priapism is a rare presentation of Chronic Myeloid Leukaemia (CML). It is also considered a medical emergency as delay in treatment may lead to impotence. Prompt medical and surgical interventions such as hydroxyurea, analgesia, phenylephrine injection and aspiration, open surgical shunting, and local radiation therapy are essential. Leukapheresis effectively reduces leukocyte count rapidly and effectively, thereby an important therapy along with other standard of care in CML-induced priapism. In the present case, priapism was the presenting symptom of CML. The same was managed with various modalities such as hydroxyurea, allopurinol, antibiotics, analgesics, sedatives, phenylephrine injection, and aspiration but failed to reduce priapism pain. With a single cycle of leukapheresis, priapism pain could be reduced significantly.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ajts.ajts_160_21","type":"journal-article","created":{"date-parts":[[2022,7,30]],"date-time":"2022-07-30T09:04:57Z","timestamp":1659171897000},"page":"124-127","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Effect of leukapheresis on pain reduction in leukemic priapism"],"prefix":"10.4103","volume":"16","author":[{"given":"Shahida","family":"Noushad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dibyajyoti","family":"Sahoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhishekh","family":"Basavarajegowda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esha","family":"Toora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Purshotam","family":"Paudel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20-20240830","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1046\/j.1464-410X.2002.02825.x","article-title":"The aetiology, pathogenesis and management of priapism","volume":"90","author":"Keoghane","year":"2002","journal-title":"BJU Int"},{"key":"R2-20-20240830","first-page":"8","article-title":"Targeted chronic myeloid leukemia therapy: Seeking a cure","volume":"13","author":"Fausel","year":"2007","journal-title":"J Manag Care Pharm"},{"key":"R3-20-20240830","first-page":"51","article-title":"Treatments for chronic myeloid leukemia: A qualitative systematic review","volume":"3","author":"Ferdinand","year":"2012","journal-title":"J Blood Med"},{"key":"R4-20-20240830","first-page":"76","article-title":"Chronic myeloid leukemia presenting as priapism: A report of 2 cases and review of literature","volume":"15","author":"Ocheni","year":"2010","journal-title":"J Coll Med"},{"key":"R5-20-20240830","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1182\/blood.V63.5.1230.1230","article-title":"Hyperleukocytosis and leukostasis: Common features of childhood chronic myelogenous leukemia","volume":"63","author":"Rowe","year":"1984","journal-title":"Blood"},{"key":"R6-20-20240830","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1111\/j.1442-2042.2004.00872.x","article-title":"Priapism secondary to leukemia: Effective management with prompt leukapheresis","volume":"11","author":"Ponniah","year":"2004","journal-title":"Int J Urol"},{"key":"R7-20-20240830","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1002\/pbc.21628","article-title":"Conservative management of priapism secondary to leukemia","volume":"51","author":"Castagnetti","year":"2008","journal-title":"Pediatr Blood Cancer"},{"key":"R8-20-20240830","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1111\/j.1744-9987.2007.00417.x","article-title":"A case report of therapeutic leukapheresis in an adult with chronic myelogenous leukemia presenting with hyperleukocytosis and leukostasis","volume":"11","author":"Shafique","year":"2007","journal-title":"Ther Apher Dial"},{"key":"R9-20-20240830","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1002\/jca.21705","article-title":"Guidelines on the use of therapeutic apheresis in clinical practice \u2013 Evidence-based approach from the writing committee of the American society for apheresis: The eighth special issue","volume":"34","author":"Padmanabhan","year":"2019","journal-title":"J Clin Apher"}],"container-title":["Asian Journal of Transfusion Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ajts.ajts_160_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:31:43Z","timestamp":1787772703000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ajts.ajts_160_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/ajts.ajts_160_21","relation":{},"ISSN":["0973-6247"],"issn-type":[{"value":"0973-6247","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1]]}}}