{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:35:50Z","timestamp":1787070950023,"version":"build-2736575974"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T00:00:00Z","timestamp":1664323200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>INTRODUCTION:<\/jats:title>\n                    <jats:p>Restless legs syndrome (RLS) is characterized by an urge to move the legs or arms, associated with uncomfortable sensations. Frequent blood donation is one of the known risk factors for RLS. Earlier studies have shown that the prevalence of RLS varies between 4% and 18% among blood donors. The present study was done to assess the prevalence of RLS among repeat blood donors and to find out its correlates in Indian population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>MATERIALS AND METHODS:<\/jats:title>\n                    <jats:p>This study was done for a period of 1 year from April 2019 to March 2020. Two hundred donors who fulfilled the definition of \u201cregular donor\u201d by National AIDS Control Organization were enrolled by convenient sampling. Responses to the Hindi version of CHRLS questionnaire for RLS were noted, and history of number of previous blood donations was taken. Estimation of red cell indices and serum ferritin levels was also done.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>Two hundred donors were selected for analysis. Out of which, 198 donors were males (99%). RLS was reported in only four donors (2%) and all of them were males. This was comparable to population prevalence of RLS reported in this region.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>The prevalence of RLS among repeat blood donors in Indian population was comparable to the general population. Our findings could be reassuring for the frequent donors. Inclusion of basic questions on symptoms of RLS in the donor screening questionnaire can be useful in detecting impending iron deficiency, though its impact on a big scale is doubtful.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ajts.ajts_181_21","type":"journal-article","created":{"date-parts":[[2022,9,27]],"date-time":"2022-09-27T04:48:23Z","timestamp":1664254103000},"page":"104-107","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Restless legs syndrome in frequent blood donors and its relationship with ferritin levels and red cell indices"],"prefix":"10.4103","volume":"19","author":[{"given":"Davood U.","family":"Bava","sequence":"first","affiliation":[{"name":"Department of Transfusion Medicine, AIIMS, Rishikesh, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gita","family":"Negi","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, AIIMS, Rishikesh, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravi","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, AIIMS, Rishikesh, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sushant Kumar","family":"Meinia","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, AIIMS, Rishikesh, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranjan","family":"Mukharjee","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, AIIMS, Rishikesh, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aswin K.","family":"Mohan","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, AIIMS, Rishikesh, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,9,28]]},"reference":[{"key":"R1-20260422","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1002\/mds.870100517","article-title":"Toward a better definition of the restless legs syndrome. 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Prevention of anaemia in blood donors: Iron or not iron?","volume":"11","author":"Deneys","year":"2013","journal-title":"Blood Transfusion"},{"key":"R16-20260422","doi-asserted-by":"crossref","first-page":"52","DOI":"10.4065\/78.1.52","article-title":"Multiple blood donations associated with iron deficiency in patients with restless legs syndrome","volume":"78","author":"Silber","year":"2003","journal-title":"Mayo Clin Proc"},{"key":"R17-20260422","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.transci.2015.09.002","article-title":"Importance of donor history of restless leg syndrome and pica to asses iron deficiency","volume":"54","author":"Singh","year":"2016","journal-title":"Transfus Apher Sci"},{"key":"R18-20260422","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1016\/j.sleep.2008.10.007","article-title":"Validation of the self-completed Cambridge-Hopkins questionnaire (CH-RLSq) for ascertainment of restless legs syndrome (RLS) in a population survey","volume":"10","author":"Allen","year":"2009","journal-title":"Sleep Med"},{"key":"R19-20260422","doi-asserted-by":"crossref","first-page":"303","DOI":"10.4103\/0972-2327.162290","article-title":"Hindi translation and validation of Cambridge-Hopkins Diagnostic Questionnaire for RLS (CHRLSq)","volume":"18","author":"Gupta","year":"2015","journal-title":"Ann Indian Acad Neurol"},{"key":"R21-20260422","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.sleep.2006.11.004","article-title":"Restless legs syndrome in an Indian urban population","volume":"9","author":"Rangarajan","year":"2007","journal-title":"Sleep Med"}],"container-title":["Asian Journal of Transfusion Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ajts.ajts_181_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:39:27Z","timestamp":1787067567000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ajts.ajts_181_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,28]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/ajts.ajts_181_21","relation":{},"ISSN":["0973-6247","1998-3565"],"issn-type":[{"value":"0973-6247","type":"print"},{"value":"1998-3565","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,28]]},"assertion":[{"value":"2021-12-14","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-06","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}