{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T15:51:43Z","timestamp":1792511503654,"version":"4.5.0"},"reference-count":75,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>Limitation of standard coagulation tests in early detection of coagulopathy leads to empirical decision-making for the management of the coagulopathy, which in many cases is accompanied by improper transfusion. Some studies have investigated the role of rotational thromboelastometry (ROTEM) in reducing the need for blood products in different clinical conditions, which have been associated with different results. Whether ROTEM as a point of care test reduces the need for transfusion in all clinical settings is still a question. A brief introduction of methodology of ROTEM and its role in patient blood management (PBM) approach is explored in this review. Search was performed to find literature describing ROTEM applied for decrease in transfusion requirements. Specific search terms were \u201cThromboelastometry,\u201d \u201cROTEM,\u201d \u201cCardiac surgical procedures,\u201d \u201cTrauma,\u201d \u201cwounds and injuries\u201d \u201cLiver transplantation,\u201d \u201cobstetric\u201d \u201cTransfusion,\u201d and \u201cPBM.\u201d we reached to 75 publications for this review after application of our search strategy. The number of publications in the field of obstetric was insufficient for review and conclusion. The available evidence supports the helpfulness of ROTEM test in reducing the need for blood transfusions in surgery or trauma. However, it is need to further investigation to evaluate the benefit and efficacy of ROTEM in other medical conditions such as obstetric hemorrhage.<\/jats:p>","DOI":"10.4103\/ajts.ajts_18_23","type":"journal-article","created":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T12:07:30Z","timestamp":1751371650000},"page":"130-137","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Rotational thromboelastometry and patient blood management: A narrative review"],"prefix":"10.4103","volume":"19","author":[{"given":"Elham","family":"Khalaf-Adeli","sequence":"first","affiliation":[{"name":"Department of Hematology, Faculty of Paramedical Sciences, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran"},{"name":"Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Tobeyani","sequence":"additional","affiliation":[{"name":"Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,6,30]]},"reference":[{"key":"R1-20260422","first-page":"e21772","article-title":"Blood transfusion practice in a referral cardiovascular center in Tehran, Iran: A critical point of view","volume":"3","author":"Alizadeh-Ghavidel","year":"2014","journal-title":"Res Cardiovasc Med"},{"key":"R2-20260422","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1111\/j.1423-0410.2010.01349.x","article-title":"The epidemiology of red cell transfusion","volume":"99","author":"Barr","year":"2010","journal-title":"Vox Sang"},{"key":"R3-20260422","first-page":"191","article-title":"Patient Blood Management: A revolutionary approach to transfusion medicine","volume":"17","author":"Franchini","year":"2019","journal-title":"Blood Transfus"},{"key":"R4-20260422","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1016\/j.jtcvs.2013.10.051","article-title":"Transfusion practice varies widely in cardiac surgery: Results from a national registry","volume":"147","author":"McQuilten","year":"2014","journal-title":"J Thorac Cardiovasc Surg"},{"key":"R5-20260422","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.cca.2013.09.030","article-title":"Utilization management in the blood transfusion service","volume":"427","author":"Pe\u00f1a","year":"2014","journal-title":"Clin Chim Acta"},{"key":"R6-20260422","first-page":"719","article-title":"Transfusion of blood and blood products: Indications and complications","volume":"83","author":"Sharma","year":"2011","journal-title":"Am Fam Physician"},{"key":"R7-20260422","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1111\/j.1537-2995.2008.01666.x","article-title":"The ongoing variability in blood transfusion practices in cardiac surgery","volume":"48","author":"Snyder-Ramos","year":"2008","journal-title":"Transfusion"},{"key":"R8-20260422","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.3324\/haematol.2009.010934","article-title":"Endothelial cell-derived microparticles induce plasmacytoid dendritic cell maturation: Potential implications in inflammatory diseases","volume":"94","author":"Angelot","year":"2009","journal-title":"Haematologica"},{"key":"R9-20260422","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1055\/s-0037-1615947","article-title":"A cell-based model of hemostasis","volume":"85","author":"Hoffman","year":"2001","journal-title":"Thromb Haemost"},{"key":"R10-20260422","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1476-4431.2009.00389.x","article-title":"The cell-based model of coagulation","volume":"19","author":"Smith","year":"2009","journal-title":"J Vet Emerg Crit Care (San Antonio)"},{"key":"R11-20260422","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1093\/ajcp\/106.1.87","article-title":"Changes in blood coagulation during and following cardiopulmonary bypass: Lack of correlation with clinical bleeding","volume":"106","author":"Gelb","year":"1996","journal-title":"Am J Clin Pathol"},{"key":"R12-20260422","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1177\/1089253214534782","article-title":"A 2014 update on coagulation management for cardiopulmonary bypass","volume":"18","author":"Thiele","year":"2014","journal-title":"Semin Cardiothorac Vasc Anesth"},{"key":"R13-20260422","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1093\/bja\/aeu303","article-title":"Usefulness of standard plasma coagulation tests in the management of perioperative coagulopathic bleeding: Is there any evidence?","volume":"114","author":"Haas","year":"2015","journal-title":"Br J Anaesth"},{"key":"R14-20260422","doi-asserted-by":"crossref","first-page":"100582","DOI":"10.1016\/j.blre.2019.05.006","article-title":"The central role of thrombin in bleeding disorders","volume":"38","author":"Negrier","year":"2019","journal-title":"Blood Rev"},{"key":"R15-20260422","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1093\/ajcp\/aqz074","article-title":"The utility of thromboelastography to guide blood product transfusion","volume":"152","author":"Schmidt","year":"2019","journal-title":"Am J Clin Pathol"},{"key":"R16-20260422","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1097\/TA.0000000000002206","article-title":"Thromboelastography and rotational thromboelastometry for the surgical intensivist: A narrative review","volume":"86","author":"Drumheller","year":"2019","journal-title":"J Trauma Acute Care Surg"},{"key":"R17-20260422","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/j.jtcvs.2010.04.043","article-title":"Thromboelastometrically guided transfusion protocol during aortic surgery with circulatory arrest: A prospective, randomized trial","volume":"140","author":"Girdauskas","year":"2010","journal-title":"J Thorac Cardiovasc Surg"},{"key":"R18-20260422","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1097\/ALN.0b013e31823497dd","article-title":"First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: A retrospective, single-center cohort study","volume":"115","author":"G\u00f6rlinger","year":"2011","journal-title":"Anesthesiology"},{"key":"R19-20260422","doi-asserted-by":"crossref","first-page":"297","DOI":"10.4097\/kja.19169","article-title":"The role of evidence-based algorithms for rotational thromboelastometry-guided bleeding management","volume":"72","author":"G\u00f6rlinger","year":"2019","journal-title":"Korean J Anesthesiol"},{"key":"R20-20260422","first-page":"1320","article-title":"Thromboelastometry for guiding bleeding management of the critically ill patient: A systematic review of the literature","volume":"80","author":"Haas","year":"2014","journal-title":"Minerva Anestesiol"},{"key":"R21-20260422","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1186\/s12871-019-0767-x","article-title":"Safety of coagulation factor concentrates guided by ROTEM\u2122-analyses in liver transplantation: Results from 372 procedures","volume":"19","author":"Hartmann","year":"2019","journal-title":"BMC Anesthesiol"},{"key":"R22-20260422","first-page":"244","article-title":"Introduction of thromboelastometry-guided administration of fresh-frozen plasma is associated with decreased allogeneic blood transfusions and post-operative blood loss in cardiopulmonary-bypass surgery","volume":"16","author":"Ichikawa","year":"2018","journal-title":"Blood Transfus"},{"key":"R23-20260422","doi-asserted-by":"crossref","first-page":"300","DOI":"10.15171\/jcvtr.2019.48","article-title":"Comparison of standard coagulation testing with thromboelastometry tests in cardiac surgery","volume":"11","author":"Khalaf-Adeli","year":"2019","journal-title":"J Cardiovasc Thorac Res"},{"key":"R24-20260422","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1055\/s-0035-1550434","article-title":"Clinical utility of viscoelastic tests of coagulation (TEG\/ROTEM) in patients with liver disease and during liver transplantation","volume":"41","author":"Mallett","year":"2015","journal-title":"Semin Thromb Hemost"},{"key":"R25-20260422","first-page":"39","article-title":"Effects of the preoperative administration of a fibrinogen concentrate on bleeding and transfusion requirements in cardiac surgery","volume":"20","author":"Khalaf-Adeli","year":"2019","journal-title":"Iran Heart J"},{"key":"R26-20260422","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1111\/vox.12279","article-title":"Protocol guided bleeding management improves cardiac surgery patient outcomes","volume":"109","author":"Pearse","year":"2015","journal-title":"Vox Sang"},{"key":"R27-20260422","doi-asserted-by":"crossref","first-page":"447","DOI":"10.23736\/S0375-9393.17.12023-7","article-title":"Assessment of rotational thromboelastometry for the prediction of red blood cell requirements in orthotopic liver transplantation","volume":"84","author":"Sabate","year":"2018","journal-title":"Minerva Anestesiol"},{"key":"R28-20260422","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1182\/hematology.2020000090","article-title":"\u201cTEG talk\u201d: Expanding clinical roles for thromboelastography and rotational thromboelastometry","volume":"2020","author":"Selby","year":"2020","journal-title":"Hematology Am Soc Hematol Educ Program"},{"key":"R29-20260422","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1186\/s13054-014-0637-3","article-title":"TEG\u00ae- or ROTEM\u00ae-based individualized goal-directed coagulation algorithms: Don\u2019t wait-act now!","volume":"18","author":"Spahn","year":"2014","journal-title":"Crit Care"},{"key":"R30-20260422","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1002\/ajh.23599","article-title":"TEG and ROTEM: Technology and clinical applications","volume":"89","author":"Whiting","year":"2014","journal-title":"Am J Hematol"},{"key":"R31-20260422","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-3148.2006.00709.x","article-title":"A survey of the demographics of blood use","volume":"17","author":"Cobain","year":"2007","journal-title":"Transfus Med"},{"key":"R32-20260422","doi-asserted-by":"crossref","first-page":"2068","DOI":"10.1161\/CIRCULATIONAHA.110.936773","article-title":"Pathophysiology of bleeding and clotting in the cardiac surgery patient: From vascular endothelium to circulatory assist device surface","volume":"122","author":"Achneck","year":"2010","journal-title":"Circulation"},{"key":"R33-20260422","doi-asserted-by":"crossref","first-page":"197","DOI":"10.3109\/10408363.2010.549291","article-title":"The coagulopathy of cardiopulmonary bypass","volume":"47","author":"Besser","year":"2010","journal-title":"Crit Rev Clin Lab Sci"},{"key":"R34-20260422","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1007\/s00134-004-2388-0","article-title":"Coagulation disorders of cardiopulmonary bypass: A review","volume":"30","author":"Paparella","year":"2004","journal-title":"Intensive Care Med"},{"key":"R35-20260422","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.thromres.2011.02.022","article-title":"Fibrin formation is more impaired than thrombin generation and platelets immediately following cardiac surgery","volume":"128","author":"Solomon","year":"2011","journal-title":"Thromb Res"},{"key":"R36-20260422","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1007\/s11748-020-01399-y","article-title":"Hypothermic circulatory arrest induced coagulopathy: Rotational thromboelastometry analysis","volume":"68","author":"Ise","year":"2020","journal-title":"Gen Thorac Cardiovasc Surg"},{"key":"R37-20260422","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1053\/j.jvca.2017.08.025","article-title":"Prediction of postoperative blood loss using thromboelastometry in adult cardiac surgery: Cohort study and systematic review","volume":"32","author":"Meesters","year":"2018","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"R38-20260422","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1007\/s12288-020-01375-9","article-title":"Role of using a thromboelastometry-based protocol for transfusion management in combined coronary artery bypass grafting and valve surgery: A randomized clinical trail","volume":"37","author":"Khalaf-Adeli","year":"2021","journal-title":"Indian J Hematol Blood Transfus"},{"key":"R39-20260422","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1093\/bja\/aeu339","article-title":"Thromboelastometry-guided intraoperative haemostatic management reduces bleeding and red cell transfusion after paediatric cardiac surgery","volume":"114","author":"Nakayama","year":"2015","journal-title":"Br J Anaesth"},{"key":"R40-20260422","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1111\/bjh.14476","article-title":"Exacerbation of oxidative stress during sickle vaso-occlusive crisis is associated with decreased anti-band 3 autoantibodies rate and increased red blood cell-derived microparticle level: A prospective study","volume":"176","author":"Hierso","year":"2017","journal-title":"Br J Haematol"},{"key":"R41-20260422","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1053\/j.jvca.2018.08.203","article-title":"Shifts of transfusion demand in cardiac surgery after implementation of rotational thromboelastometry-guided transfusion protocols: Analysis of the HEROES-CS (HEmostasis Registry of patiEntS in Cardiac Surgery) observational, prospective open cohort database","volume":"33","author":"Kuiper","year":"2019","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"R42-20260422","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1016\/j.transproceed.2012.05.004","article-title":"Coagulopathy management in liver transplantation","volume":"44","author":"Sabate","year":"2012","journal-title":"Transplant Proc"},{"key":"R43-20260422","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.cld.2016.12.003","article-title":"Coagulopathy before and after liver transplantation: From the hepatic to the systemic circulatory systems","volume":"21","author":"Stine","year":"2017","journal-title":"Clin Liver Dis"},{"key":"R44-20260422","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1093\/bja\/aex122","article-title":"Assessment of standard laboratory tests and rotational thromboelastometry for the prediction of postoperative bleeding in liver transplantation","volume":"119","author":"D\u00f6tsch","year":"2017","journal-title":"Br J Anaesth"},{"key":"R45-20260422","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1159\/000381733","article-title":"Preoperative thromboelastometry as a predictor of transfusion requirements during adult living donor liver transplantation","volume":"42","author":"Fayed","year":"2015","journal-title":"Transfus Med Hemother"},{"key":"R46-20260422","doi-asserted-by":"crossref","first-page":"21","DOI":"10.4103\/ija.IJA_334_18","article-title":"Correlation of early ROTEM parameters with conventional coagulation tests in patients with chronic liver disease undergoing liver transplant","volume":"63","author":"Hashir","year":"2019","journal-title":"Indian J Anaesth"},{"key":"R47-20260422","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/lt.24030","article-title":"Management of bleeding and transfusion during liver transplantation before and after the introduction of a rotational thromboelastometry-based algorithm","volume":"21","author":"Roullet","year":"2015","journal-title":"Liver Transpl"},{"key":"R48-20260422","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1093\/bja\/aeq022","article-title":"Rotation thromboelastometry detects thrombocytopenia and hypofibrinogenaemia during orthotopic liver transplantation","volume":"104","author":"Roullet","year":"2010","journal-title":"Br J Anaesth"},{"key":"R49-20260422","first-page":"19","article-title":"The use of thromboelastometry in the assessment of hemostasis during orthotopic liver transplantation reduces the demand for blood products","volume":"15","author":"Trzebicki","year":"2010","journal-title":"Ann Transplant"},{"key":"R50-20260422","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1093\/bja\/aet325","article-title":"Five-minute parameter of thromboelastometry is sufficient to detect thrombocytopenia and hypofibrinogenaemia in patients undergoing liver transplantation","volume":"112","author":"Song","year":"2014","journal-title":"Br J Anaesth"},{"key":"R51-20260422","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1093\/bja\/aew344","article-title":"Rotation thromboelastometry velocity curve predicts blood loss during liver transplantation","volume":"117","author":"Tafur","year":"2016","journal-title":"Br J Anaesth"},{"key":"R52-20260422","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1590\/s1679-45082017md3903","article-title":"The role of thromboelastometry in the assessment and treatment of coagulopathy in liver transplant patients","volume":"15","author":"Zamper","year":"2017","journal-title":"Einstein (Sao Paulo)"},{"key":"R53-20260422","doi-asserted-by":"crossref","first-page":"916","DOI":"10.5604\/01.3001.0010.5283","article-title":"Rotational thromboelastometry or conventional coagulation tests in liver transplantation: Comparing blood loss, transfusions, and cost","volume":"16","author":"Smart","year":"2017","journal-title":"Ann Hepatol"},{"key":"R54-20260422","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1097\/EJA.0000000000001084","article-title":"The use of a thromboelastometry-based algorithm reduces the need for blood product transfusion during orthotopic liver transplantation: A randomised controlled study","volume":"36","author":"Bonnet","year":"2019","journal-title":"Eur J Anaesthesiol"},{"key":"R55-20260422","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1097\/EJA.0000000000001183","article-title":"Thromboelastometry-based algorithms and the need for transfusion during liver transplantation","volume":"37","author":"Sabate","year":"2020","journal-title":"Eur J Anaesthesiol"},{"key":"R56-20260422","doi-asserted-by":"crossref","first-page":"222","DOI":"10.6002\/ect.2017.0236","article-title":"Use of rotational thromboelastometry in liver transplantation is associated with reduced transfusion requirements","volume":"17","author":"Schumacher","year":"2019","journal-title":"Exp Clin Transplant"},{"key":"R57-20260422","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.ijsu.2015.09.036","article-title":"Thromboelastography and rotational thromboelastometry use in trauma","volume":"33","author":"Abdelfattah","year":"2016","journal-title":"Int J Surg"},{"key":"R58-20260422","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1182\/blood-2016-01-636423","article-title":"Advances in the understanding of trauma-induced coagulopathy","volume":"128","author":"Chang","year":"2016","journal-title":"Blood"},{"key":"R59-20260422","doi-asserted-by":"crossref","first-page":"54","DOI":"10.4037\/ccn2014133","article-title":"Trauma-induced coagulopathy","volume":"34","author":"Katrancha","year":"2014","journal-title":"Crit Care Nurse"},{"key":"R60-20260422","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1186\/s13054-015-0817-9","article-title":"Trauma-induced coagulopathy: Impact of the early coagulation support protocol on blood product consumption, mortality and costs","volume":"19","author":"Nardi","year":"2015","journal-title":"Crit Care"},{"key":"R61-20260422","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1080\/17843286.2017.1422311","article-title":"Thromboelastometry in trauma care: A place in the 2018 Belgian health care system?","volume":"73","author":"Tonglet","year":"2018","journal-title":"Acta Clin Belg"},{"key":"R62-20260422","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1111\/j.1399-6576.2009.02132.x","article-title":"Successful rotational thromboelastometry-guided treatment of traumatic haemorrhage, hyperfibrinolysis and coagulopathy","volume":"54","author":"Brenni","year":"2010","journal-title":"Acta Anaesthesiol Scand"},{"key":"R63-20260422","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1186\/s13054-015-0823-y","article-title":"Detection of acute traumatic coagulopathy and massive transfusion requirements by means of rotational thromboelastometry: An international prospective validation study","volume":"19","author":"Hagemo","year":"2015","journal-title":"Crit Care"},{"key":"R64-20260422","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1111\/anae.14297","article-title":"Using rotational thromboelastometry clot firmness at 5 minutes (ROTEM(\u00ae) EXTEM A5) to predict massive transfusion and in-hospital mortality in trauma: A retrospective analysis of 1146 patients","volume":"73","author":"Kelly","year":"2018","journal-title":"Anaesthesia"},{"key":"R65-20260422","first-page":"CD010438","article-title":"Thromboelastography (TEG) and rotational thromboelastometry (ROTEM) for trauma induced coagulopathy in adult trauma patients with bleeding","volume":"2015","author":"Hunt","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"R66-20260422","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1186\/s13054-014-0518-9","article-title":"Effect of thromboelastography (TEG\u00ae) and rotational thromboelastometry (ROTEM\u00ae) on diagnosis of coagulopathy, transfusion guidance and mortality in trauma: Descriptive systematic review","volume":"18","author":"Da Luz","year":"2014","journal-title":"Crit Care"},{"key":"R67-20260422","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1186\/s13049-016-0308-2","article-title":"A systematic review on the rotational thrombelastometry (ROTEM\u00ae) values for the diagnosis of coagulopathy, prediction and guidance of blood transfusion and prediction of mortality in trauma patients","volume":"24","author":"Veigas","year":"2016","journal-title":"Scand J Trauma Resusc Emerg Med"},{"key":"R68-20260422","first-page":"2022","article-title":"The addition of ROTEM parameter did not significantly improve the massive transfusion prediction in severe trauma patients","author":"Baik","year":"2022","journal-title":"Emerg Med Int"},{"key":"R69-20260422","article-title":"Implementation of point-of-care ROTEM\u00ae into a trauma major haemorrhage protocol: A before and after study","author":"Campbell","year":"2020","journal-title":"Emerg Med Australas"},{"key":"R70-20260422","doi-asserted-by":"crossref","first-page":"e229508","DOI":"10.1136\/bcr-2019-229508","article-title":"Successful ROTEM-guided transfusion therapy in a case of rural paediatric trauma","volume":"12","author":"Choy","year":"2019","journal-title":"BMJ Case Rep"},{"key":"R71-20260422","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1111\/trf.15176","article-title":"A prospective evaluation of thromboelastometry (ROTEM) to identify acute traumatic coagulopathy and predict massive transfusion in military trauma patients in Afghanistan","volume":"59","author":"Cohen","year":"2019","journal-title":"Transfusion"},{"key":"R72-20260422","doi-asserted-by":"crossref","first-page":"5195","DOI":"10.1177\/0300060518794092","article-title":"Rotation thromboelastometry (ROTEM) enables improved outcomes in the pediatric trauma population","volume":"46","author":"Deng","year":"2018","journal-title":"J Int Med Res"},{"key":"R73-20260422","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1111\/1742-6723.13939","article-title":"Rotational thromboelastometry in children presenting to an Australian major trauma centre: A retrospective cohort study","volume":"34","author":"George","year":"2022","journal-title":"Emerg Med Australas"},{"key":"R74-20260422","doi-asserted-by":"crossref","first-page":"e922879","DOI":"10.12659\/MSM.922879","article-title":"Implementation of thromboelastometry for coagulation management in isolated traumatic brain injury patients undergoing craniotomy","volume":"26","author":"Rimaitis","year":"2020","journal-title":"Med Sci Monit"},{"key":"R75-20260422","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1093\/bja\/aer158","article-title":"Prevalence and impact of abnormal ROTEM(R) assays in severe blunt trauma: Results of the \u2018Diagnosis and Treatment of Trauma-Induced Coagulopathy (DIA-TRE-TIC) study\u2019","volume":"107","author":"Tauber","year":"2011","journal-title":"Br J Anaesth"}],"container-title":["Asian Journal of Transfusion Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ajts.ajts_18_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:39:29Z","timestamp":1787067569000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ajts.ajts_18_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":75,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/ajts.ajts_18_23","relation":{},"ISSN":["0973-6247","1998-3565"],"issn-type":[{"value":"0973-6247","type":"print"},{"value":"1998-3565","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2023-01-24","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-14","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}