{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:35:00Z","timestamp":1787758500540,"version":"build-2784847793"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,7]]},"abstract":"Abstract<\/jats:title>\n \n BACKGROUND:<\/jats:title>\n Liver transplantation (LT) is a complicated surgical procedure with high risk for massive intraoperative blood loss due to pre-existing coagulopathy, portosystemic shunts with collateral circulations, and splenomegaly. The transfusion service will direct most of their resources toward LT programs with great impact on cost. The purpose of this study was to evaluate single center transfusion strategies and to identify the risk factors associated with the intraoperative blood loss and blood transfusion.<\/jats:p>\n <\/jats:sec>\n \n METHODS:<\/jats:title>\n The study includes 18 patients who underwent LT at Hospital Selayang between January 2020 and December 2020. Retrospective analysis of data included preoperative assessment of coagulopathy, intraoperative blood loss, and blood component transfusion.<\/jats:p>\n <\/jats:sec>\n \n RESULTS:<\/jats:title>\n \n The mean age in the study group was 36.4 \u00b1 12.68 years. The mean intraoperative blood loss was 4450 \u00b1 1646 ml requiring 4.17 \u00b1 3.3 packed red blood cell (PRBC) units, 7.56 \u00b1 5.5 platelet units, and 9.50 \u00b1 6.0 fresh-frozen plasma units. The independent risk factor for high blood loss (HBL) group was lower preoperative platelet count and it is statistically significant (\n P<\/jats:italic>\n = 0.024). The HBL group is associated with higher usage of PRBC (\n P<\/jats:italic>\n = 0.024) and platelet units (\n P<\/jats:italic>\n = 0.031) and it is statistically significant. The length of stay (LOS) in intensive care unit (ICU) averaging 8.6 \u00b1 4.95 days, and there is no significant differences comparing the HBL and LBL group (\n P<\/jats:italic>\n = 0.552). The mortality <90 days for all recipients was 22.2%.\n <\/jats:p>\n <\/jats:sec>\n \n CONCLUSION:<\/jats:title>\n The preoperative platelet count for is the most important factor associated with HBL in LT procedure. The usage of PRBC and platelet units was statistically higher in the HBL group. Comparing HBL and LBL patients, there is no difference in terms of the LOS in ICU postoperatively. A larger sample size would be needed in view of relatively small sample size.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ajts.ajts_38_21","type":"journal-article","created":{"date-parts":[[2022,9,27]],"date-time":"2022-09-27T04:48:23Z","timestamp":1664254103000},"page":"251-255","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Intraoperative blood loss and blood transfusion requirement among liver transplant recipients: A national single-center experience 2020"],"prefix":"10.4103","volume":"17","author":[{"given":"Mohd Faeiz","family":"Yusop","sequence":"first","affiliation":[{"name":"Department of Pathology, Hospital Selayang, Selangor, Ministry of Health, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norlida Mohamad","family":"Tahir","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hospital Selayang, Selangor, Ministry of Health, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharifah Mai Sarah Syed","family":"Azim","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hospital Selayang, Selangor, Ministry of Health, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ameera Ashyila","family":"Kamaruzaman","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hospital Selayang, Selangor, Ministry of Health, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nur Raihan Mohd","family":"Hata","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hospital Selayang, Selangor, Ministry of Health, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arvend","family":"Kugaan","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hospital Selayang, Selangor, Ministry of Health, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohd Fairuz","family":"Osman","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hospital Selayang, Selangor, Ministry of Health, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tengku Norita Tengku","family":"Yazid","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hospital Selayang, Selangor, Ministry of Health, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suryati","family":"Mokhtar","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary, Hospital Selayang, Selangor, Ministry of Health, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haniza","family":"Omar","sequence":"additional","affiliation":[{"name":"Department of Hepatology, Hospital Selayang, Selangor, Ministry of Health, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad Suhaimi","family":"Amir","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Unit, Hospital Selayang, Selangor, Ministry of Health, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,9,28]]},"reference":[{"key":"R1-20240830","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1046\/j.1537-2995.1985.25285169201.x","article-title":"Blood transfusion in liver transplantation","volume":"25","author":"Butler","year":"1985","journal-title":"Transfusion"},{"key":"R2-20240830","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/S0140-6736(76)91794-3","article-title":"Correction of abnormal coagulation in chronic liver disease by combined use of fresh-frozen plasma and prothrombin complex 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A national single center experience","volume":"21","author":"Tomescu","year":"2014","journal-title":"J Rom Anest Terap Int"},{"key":"R10-20240830","doi-asserted-by":"crossref","first-page":"2153","DOI":"10.1016\/S0041-1345(02)02887-7","article-title":"Identification of preoperative predictors of intraoperative blood transfusion requirement in orthotopic liver transplantation","volume":"34","author":"Pirat","year":"2002","journal-title":"Transplant Proc"},{"key":"R11-20240830","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1097\/TP.0000000000002246","article-title":"Recipient age and mortality after liver transplantation:A population-based cohort study","volume":"102","author":"Gil","year":"2018","journal-title":"Transplantation"}],"container-title":["Asian Journal of Transfusion Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ajts.ajts_38_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:15:48Z","timestamp":1787757348000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ajts.ajts_38_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,28]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/ajts.ajts_38_21","relation":{},"ISSN":["0973-6247","1998-3565"],"issn-type":[{"value":"0973-6247","type":"print"},{"value":"1998-3565","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,28]]},"assertion":[{"value":"2021-03-25","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-29","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}