{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:22:30Z","timestamp":1787840550717,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T00:00:00Z","timestamp":1653523200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,7]]},"abstract":"Abstract<\/jats:title>\n \n CONTEXT:<\/jats:title>\n On exposure to SARS-CoV-2 in participants anti-SARS-CoV-2 antibodies are expected to appear as a humoral response. Furthermore, various factors affect their expression.<\/jats:p>\n <\/jats:sec>\n \n AIMS:<\/jats:title>\n The aim of this study is to investigate the humoral response of COVID-19-recovered participants and correlation with duration of disease, duration of COVID positive to date of test, occupation, blood group, age group, weight, gender, and symptoms of anti-SARS-CoV-2 antibodies.<\/jats:p>\n <\/jats:sec>\n \n SETTINGS AND DESIGN:<\/jats:title>\n This prospective observational study was conducted at the Department of Transfusion Medicine, at a tertiary care center in North India.<\/jats:p>\n <\/jats:sec>\n \n METHODS:<\/jats:title>\n Seventy-two participants were tested for anti-SARS-CoV-2 antibodies on chemiluminescent microparticle immunoassay postgetting COVID negative.<\/jats:p>\n <\/jats:sec>\n \n STATISTICAL ANALYSIS:<\/jats:title>\n The data were analyzed using Kruskal\u2013Wallis and Mann\u2013Whitney test. To correlate variables such as duration of disease, duration of COVID positive to date of test of immunoglobulin G (IgG), occupation, blood group, weight, gender, symptoms, and age group Chi-square test were used.<\/jats:p>\n <\/jats:sec>\n \n RESULTS:<\/jats:title>\n \n The correlation of anti-SARS-CoV-2 antibodies with a duration of disease (\n P<\/jats:italic>\n > 0.05), duration of COVID positive to date of test of IgG (\n P<\/jats:italic>\n > 0.05), occupation (\n P<\/jats:italic>\n > 0.05), blood group (\n P<\/jats:italic>\n > 0.05), weight (\n P<\/jats:italic>\n > 0.05), gender (\n P<\/jats:italic>\n > 0.05), and symptoms (\n P<\/jats:italic>\n > 0.05) is insignificant and whereas significant correlation with age group (\n P<\/jats:italic>\n < 0.05) seen.\n <\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS:<\/jats:title>\n A significant correlation was seen in anti-SARS-COV-2 antibodies and age group. Higher antibody levels were seen in participants of the upper extreme age group (50\u201360 years).<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ajts.ajts_56_21","type":"journal-article","created":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T02:43:12Z","timestamp":1653964992000},"page":"267-270","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Humoral response to SARS-COV-2 in COVID-19-recovered patients and correlation with various factors"],"prefix":"10.4103","volume":"19","author":[{"given":"Tulika","family":"Chandra","sequence":"first","affiliation":[{"name":"Department of Transfusion Medicine, King George\u2019s M.U, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Himanshu","sequence":"additional","affiliation":[{"name":"Department of Medicine, King George\u2019s M.U, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradeep Kumar","family":"Maurya","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, King George\u2019s M.U, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mallika","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Era Medical College, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saurabh","family":"Pandey","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, King George\u2019s M.U, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,5,26]]},"reference":[{"key":"R1-20251022","first-page":"271","article-title":"Why is it difficult to accurately predict the COVID-19 epidemic?","volume":"5","author":"Roda","year":"2020","journal-title":"Infect Dis 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SARS-CoV-2 after mild and severe COVID-19 infection and analysis of IgG non-responders","volume":"15","author":"Marklund","year":"2020","journal-title":"PLoS One"},{"key":"R7-20251022","first-page":"1","article-title":"NOTE: This preprint reports new research that has not been certified by peer review and should not be used to guide clinical practice","volume":"1","author":"Madewell","year":"2020","journal-title":"medRxiv"},{"key":"R8-20251022","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1086\/500469","article-title":"Two-year prospective study of the humoral immune response of patients with severe acute respiratory syndrome","volume":"193","author":"Liu","year":"2006","journal-title":"J Infect Dis"},{"key":"R9-20251022","doi-asserted-by":"crossref","first-page":"e0237548","DOI":"10.1371\/journal.pone.0237548","article-title":"Evaluation of SARS-CoV-2 IgG antibody response in PCR positive patients: Comparison of nine tests in relation to clinical data","volume":"15","author":"Naaber","year":"2020","journal-title":"PLoS One"},{"key":"R10-20251022","doi-asserted-by":"crossref","DOI":"10.1111\/trf.16323","article-title":"A longitudinal study of convalescent plasma (CCP) donors and correlation of ABO group, initial neutralizing antibodies (nAb ) and body mass index (BMI) with nAb and anti-nucleocapsid (NP) SARS-CoV-2 antibody kinetics: Proposals for better quality of CCP collections","author":"Wendel","year":"2021","journal-title":"Transfusion"},{"key":"R11-20251022","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1128\/CMR.00109-14","article-title":"Blood groups in infection and host susceptibility","volume":"28","author":"Cooling","year":"2015","journal-title":"Clin Microbiol Rev"}],"container-title":["Asian Journal of Transfusion Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ajts.ajts_56_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:24:52Z","timestamp":1787837092000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ajts.ajts_56_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,26]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/ajts.ajts_56_21","relation":{},"ISSN":["0973-6247","1998-3565"],"issn-type":[{"value":"0973-6247","type":"print"},{"value":"1998-3565","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,26]]},"assertion":[{"value":"2021-05-20","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-12","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}