{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:23:05Z","timestamp":1787840585741,"version":"build-2784847793"},"reference-count":3,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T00:00:00Z","timestamp":1713225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired disease caused by clonal expansion of one or more hematopoietic stem cell lines due to a somatic mutation of the phosphatidylinositol glycan anchor gene. Peripheral blood stem cell (PBSC) harvest is a high-risk procedure and the major concern was regarding the development of COVID infection in the recipient. Herein, we describe an inevitable case of PBSC harvest in a PNH patient who was already started on myeloablation and where the donor became positive 1 day before the harvest. Considering the risk\u2013benefit ratio and the need for elaborate arrangements, the initial plan for bone marrow harvesting was changed to PBSC, and hence, the harvest was performed in a COVID-designated unit. No features of graft versus host disease (GVHD) were observed in the patient. The patient was examined for signs and symptoms of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and there was no evidence of any infection after the procedure. The weekly analysis of the same was done for 1 month after PBSC and the SARS-CoV-2 status remained negative. The authors opine that PBSC from SARS-CoV-2 can be performed safely in some unpreventable situations.<\/jats:p>","DOI":"10.4103\/ajts.ajts_57_23","type":"journal-article","created":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T07:00:14Z","timestamp":1713164414000},"page":"393-395","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["A case of allogeneic peripheral blood stem cell in a paroxysmal nocturnal hemoglobinuria patient from a COVID-positive donor: Managing the unpreventable"],"prefix":"10.4103","volume":"19","author":[{"given":"Mohit","family":"Chowdhry","sequence":"first","affiliation":[{"name":"Department of Transfusion Medicine and Transplant Immunology, Indraprastha Apollo Hospitals, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prachi","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Hemato Oncology and Bone Marrow Transplant, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S Minu","family":"Lekshmi","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine and Transplant Immunology, Indraprastha Apollo Hospitals, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uday Kumar","family":"Thakur","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine and Transplant Immunology, Indraprastha Apollo Hospitals, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shishir","family":"Seth","sequence":"additional","affiliation":[{"name":"Department of Hemato Oncology and Bone Marrow Transplant, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,4,16]]},"reference":[{"key":"R3-20251022","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.1038\/s41409-020-0919-0","article-title":"The challenge of COVID-19 and hematopoietic cell transplantation;EBMT recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing CAR T-cell therapy","volume":"55","author":"Ljungman","year":"2020","journal-title":"Bone Marrow Transplant"},{"key":"R4-20251022","doi-asserted-by":"crossref","first-page":"e167","DOI":"10.1016\/S2352-3026(21)00025-9","article-title":"Allogeneic haematopoietic stem cell transplantation from SARS-CoV-2 positive donors","volume":"8","author":"Leclerc","year":"2021","journal-title":"Lancet Haematol"},{"key":"R5-20251022","doi-asserted-by":"crossref","first-page":"2359","DOI":"10.1038\/s41409-020-0969-3","article-title":"Hematopoietic stem cell transplantation from an infected SARS-CoV2 donor sibling","volume":"55","author":"Anurathapan","year":"2020","journal-title":"Bone Marrow Transplant"}],"container-title":["Asian Journal of Transfusion Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ajts.ajts_57_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:25:31Z","timestamp":1787837131000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ajts.ajts_57_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,16]]},"references-count":3,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/ajts.ajts_57_23","relation":{},"ISSN":["0973-6247","1998-3565"],"issn-type":[{"value":"0973-6247","type":"print"},{"value":"1998-3565","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,16]]},"assertion":[{"value":"2023-03-16","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-30","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}