{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:32:03Z","timestamp":1787772723417,"version":"build-2784847793"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      Testing to detect ABO incompatibility between a donor and potential transfusion recipient is the foundation on which all other pretransfusion testing is based. Sometimes, weak agglutination reactions may be obtained with reagent antibodies due to weak expression of A and B antigens on red blood cell (RBC) surface which may cause a discrepancy in blood group typing. Here, we report a patient showing discrepancy between RBCs (forward) and serum (reverse) typing. After doing detailed analysis, the blood type as a variant of blood Group A revealed. Subgroups of A are very rare phenotype of blood. Weaker subgroups of A blood group reported so far are mainly A\n                      <jats:sub>3<\/jats:sub>\n                      , A\n                      <jats:sub>end<\/jats:sub>\n                      , A\n                      <jats:sub>x<\/jats:sub>\n                      , A\n                      <jats:sub>m<\/jats:sub>\n                      , A\n                      <jats:sub>y<\/jats:sub>\n                      , and A\n                      <jats:sub>el<\/jats:sub>\n                      . We are reporting a case of a 35-year-old patient whose RBCs showed a discrepancy between cell and serum grouping during initial testing. Serological investigation included absorption elution tests and saliva tests after performing initial blood grouping. The serological characteristics of the patient's red cells were similar to A\n                      <jats:sub>3<\/jats:sub>\n                      subtype. The patient was a secretor and A and H substance was present in the saliva. Serum did not show any presence of anti-A1. The weak A phenotype identified had serological characteristics similar to A\n                      <jats:sub>3<\/jats:sub>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ajts.ajts_66_21","type":"journal-article","created":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T02:43:12Z","timestamp":1653964992000},"page":"132-134","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":9,"title":["Detection of a weaker subgroup of A in ABO blood group system"],"prefix":"10.4103","volume":"16","author":[{"given":"Gurika","family":"Chopra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manpreet","family":"Kataria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arshpreet Kaur","family":"Batra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gurkiran","family":"kaur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R3-22-20240830","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1046\/j.1365-3148.2001.00320.x","article-title":"Polymorphism and recombination events at the ABO locus: A major challenge for genomic ABO blood grouping strategies","volume":"11","author":"Olsson","year":"2001","journal-title":"Transfus Med"},{"key":"R4-22-20240830","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1053\/tmrv.2001.24591","article-title":"The ABO blood group gene: A locus of considerable genetic diversity","volume":"15","author":"Chester","year":"2001","journal-title":"Transfus Med 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genes","volume":"11","author":"Yamamoto","year":"2001","journal-title":"Transfus Med"},{"key":"R14-22-20240830","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1046\/j.1537-2995.2003.00321.x","article-title":"Systematic analysis of the ABO gene diversity within exons 6 and 7 by PCR screening reveals new ABO alleles","volume":"43","author":"Seltsam","year":"2003","journal-title":"Transfusion"},{"key":"R16-22-20240830","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1111\/j.1537-2995.2005.00558.x","article-title":"Missense mutations outside the catalytic domain of the ABO glycosyltransferase can cause weak blood group A and B phenotypes","volume":"45","author":"Seltsam","year":"2005","journal-title":"Transfusion"}],"container-title":["Asian Journal of Transfusion Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ajts.ajts_66_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:10:28Z","timestamp":1787771428000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ajts.ajts_66_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/ajts.ajts_66_21","relation":{},"ISSN":["0973-6247"],"issn-type":[{"value":"0973-6247","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1]]}}}