{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:29:27Z","timestamp":1786649367824,"version":"build-2736575974"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>This study aims to evaluate the three-dimensional (3D) changes in maxillary alveolar morphology following the application of modified nasoalveolar moulding (NAM) in Vietnamese patients with unilateral cleft lip and palate (UCLP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A cohort of UCLP patients undergoing modified NAM treatment was assessed using 3D imaging techniques to quantify alterations in maxillary alveolar morphology. Pre-treatment and post-treatment images were analysed to measure changes in alveolar width, height and overall morphology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The findings indicate significant improvements in maxillary alveolar dimensions post-NAM application, with notable increases in both the width and height of the alveolar ridge. These morphological changes are crucial for optimising surgical outcomes and enhancing the functional and aesthetic aspects of cleft lip and palate repair.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Modified NAM positively affects the maxillary alveolar morphology in Vietnamese UCLP patients, highlighting the importance of early cleft care intervention and paving the way for future research on NAM\u2019s long-term benefits.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ams.ams_116_25","type":"journal-article","created":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T06:02:13Z","timestamp":1777269733000},"page":"27-32","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Three-dimensional Changes in Maxillary Alveolar Morphology with Modified Nasoalveolar Moulding in Vietnamese Unilateral Cleft Lip and Palate Patients - A Prospective Study"],"prefix":"10.4103","volume":"16","author":[{"given":"Phuong Minh","family":"Hoang","sequence":"first","affiliation":[{"name":"Faculty of Odonto-Stomatology, Hue University of Medicine and Pharmacy, Hue University, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tien Dinh","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Faculty of Odonto-Stomatology, Hue University of Medicine and Pharmacy, Hue University, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ngoc Phuong Thanh","family":"Chau","sequence":"additional","affiliation":[{"name":"Faculty of Odonto-Stomatology, Hue University of Medicine and Pharmacy, Hue University, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vy Thi Nhat","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Faculty of Odonto-Stomatology, Hue University of Medicine and Pharmacy, Hue University, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trang Nha Tran","family":"Vo","sequence":"additional","affiliation":[{"name":"Department of General Dentistry, Odonto-Sotmatology Center, Hue Central Hospital, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nhung Thi","family":"Van","sequence":"additional","affiliation":[{"name":"Department of Odonto-Stomatology, Nghe An Obstetrics and Pediatrics Hospital, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hung Nam","family":"Ngo","sequence":"additional","affiliation":[{"name":"Department of Odonto-Stomatology, Nghe An Obstetrics and Pediatrics Hospital, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tai Tan","family":"Tran","sequence":"additional","affiliation":[{"name":"Faculty of Odonto-Stomatology, Hue University of Medicine and Pharmacy, Hue University, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,4,24]]},"reference":[{"key":"R1-20260703","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1111\/odi.14174","article-title":"Revisiting the embryogenesis of lip and palate development","volume":"28","author":"Hammond","year":"2022","journal-title":"Oral Dis"},{"key":"R3-20260703","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1177\/10556656211040015","article-title":"Maternal cigarette smoking and cleft lip and palate: A systematic review and meta-analysis","volume":"59","author":"Fell","year":"2022","journal-title":"Cleft Palate Craniofac J"},{"key":"R4-20260703","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1097\/01.JAA.0000721644.06681.06","article-title":"An overview of cleft lip and palate","volume":"33","author":"Alois","year":"2020","journal-title":"JAAPA"},{"key":"R5-20260703","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/nrg2933","article-title":"Cleft lip and palate: Understanding genetic and environmental influences","volume":"12","author":"Dixon","year":"2011","journal-title":"Nat Rev Genet"},{"key":"R6-20260703","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/S0901-5027(98)80046-5","article-title":"Experience in teaching of cleft lip and palate surgery in Asia","volume":"27","author":"Natsume","year":"1998","journal-title":"Int J Oral Maxillofac Surg"},{"key":"R7-20260703","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1597\/08-258","article-title":"Ethnic variations in the estimated prevalence of orofacial clefts in Taiwan, 2004 to 2006","volume":"48","author":"Shen","year":"2011","journal-title":"Cleft Palate Craniofac J"},{"key":"R8-20260703","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1597\/1545-1569_1999_036_0486_pnmiiw_2.3.co_2","article-title":"Presurgical nasoalveolar molding in infants with cleft lip and palate","volume":"36","author":"Grayson","year":"1999","journal-title":"Cleft Palate Craniofac J"},{"key":"R9-20260703","doi-asserted-by":"crossref","first-page":"100728","DOI":"10.1016\/j.ortho.2023.100728","article-title":"Comparison of post-surgical soft tissue changes between bilateral cleft patients treated with and without a modified nasoalveolar molding appliance: A cohort study","volume":"21","author":"Haddad","year":"2023","journal-title":"Int Orthod"},{"key":"R10-20260703","doi-asserted-by":"crossref","first-page":"4","DOI":"10.4103\/jos.jos_165_23","article-title":"Presurgical management trends and nasoalveolar molding usage for infants with cleft lip and palate in the capital of a developing country","volume":"13","author":"Al-Lami","year":"2024","journal-title":"J Orthod Sci"},{"key":"R11-20260703","doi-asserted-by":"crossref","first-page":"787e","DOI":"10.1097\/PRS.0000000000007828","article-title":"The nasoalveolar molding cleft protocol: Long-term treatment outcomes from birth to facial maturity","volume":"147","author":"Yarholar","year":"2021","journal-title":"Plast Reconstr Surg"},{"key":"R12-20260703","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1177\/1055665620980234","article-title":"Does presurgical nasoalveolar molding have a long-term effect on nasal and upper airway dimensions?","volume":"58","author":"Banari","year":"2021","journal-title":"Cleft Palate Craniofac J"},{"key":"R13-20260703","doi-asserted-by":"crossref","first-page":"103","DOI":"10.4103\/ijohs.ijohs_22_21","article-title":"Role of presurgical nasoalveolar molding in the repair of unilateral cleft lip","volume":"11","author":"Dutta","year":"2021","journal-title":"Int J Oral Health Sci"},{"key":"R14-20260703","doi-asserted-by":"crossref","first-page":"775e","DOI":"10.1097\/PRS.0000000000008463","article-title":"Long-term comparison of the aesthetic outcomes between nasoalveolar molding- and non-nasoalveolar molding-treated patients with unilateral cleft lip and palate","volume":"148","author":"Nayak","year":"2021","journal-title":"Plast Reconstr Surg"},{"key":"R15-20260703","doi-asserted-by":"crossref","first-page":"53","DOI":"10.2147\/CCIDE.S129598","article-title":"Presurgical cleft lip and palate orthopedics: An overview","volume":"9","author":"Alzain","year":"2017","journal-title":"Clin Cosmet Investig Dent"},{"key":"R16-20260703","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1597\/11-053","article-title":"Nasoalveolar molding: Prevalence of cleft centers offering NAM and who seeks it","volume":"49","author":"Sischo","year":"2012","journal-title":"Cleft Palate Craniofac J"},{"key":"R17-20260703","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1111\/ipd.13102","article-title":"Effects of nasoalveolar molding on maxillary arch dimensions and malocclusion characteristics in primary dentition patients with cleft lip and palate","volume":"34","author":"Ocak","year":"2024","journal-title":"Int J Paediatr Dent"},{"key":"R18-20260703","doi-asserted-by":"crossref","first-page":"107","DOI":"10.4103\/2348-2125.162964","article-title":"Effects of nasoalveolar molding therapy on alveolar morphology in unilateral cleft lip and palate using two different approaches","volume":"2","author":"Batra","year":"2015","journal-title":"J Cleft Lip Palate Craniofac Anom"},{"key":"R19-20260703","doi-asserted-by":"crossref","first-page":"286","DOI":"10.4041\/kjod.2019.49.5.286","article-title":"Three-dimensional evaluation of alveolar changes induced by nasoalveolar molding in infants with unilateral cleft lip and palate: A case-control study","volume":"49","author":"Burgaz","year":"2019","journal-title":"Korean J Orthod"},{"key":"R20-20260703","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.oooo.2013.06.032","article-title":"CAD presurgical nasoalveolar molding effects on the maxillary morphology in infants with UCLP","volume":"116","author":"Yu","year":"2013","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"R21-20260703","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.jcms.2003.07.004","article-title":"Nasolabial and alveolar morphology following presurgical orthopaedic treatment in complete unilateral clefts of lip, alveolus and palate","volume":"31","author":"Yamada","year":"2003","journal-title":"J Craniomaxillofac Surg"},{"key":"R22-20260703","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1097\/SCS.0000000000006148","article-title":"Novel three-dimensional coordinate system to analyze alveolar molding effects of pre-surgical nasoalveolar molding on infants with non-syndromic unilateral cleft lip and palate","volume":"31","author":"Zheng","year":"2020","journal-title":"J Craniofac Surg"},{"key":"R23-20260703","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1177\/1055665620966189","article-title":"Short-term efficacy of presurgical vacuum formed nasoalveolar molding aligners on nose, lip, and maxillary arch morphology in infants with unilateral cleft lip and palate: A prospective clinical trial","volume":"58","author":"Al Khateeb","year":"2021","journal-title":"Cleft Palate Craniofac J"},{"key":"R24-20260703","doi-asserted-by":"crossref","first-page":"1101184","DOI":"10.3389\/fped.2022.1101184","article-title":"Short-term surgical outcomes in patients with unilateral complete cleft lip and palate after presurgical nasoalveolar molding therapy: A three-dimensional anthropometric study","volume":"10","author":"Yin","year":"2022","journal-title":"Front Pediatr"},{"key":"R25-20260703","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.tripleo.2005.09.009","article-title":"Difference in alveolar molding effect and growth in the cleft segments: 3-dimensional analysis of unilateral cleft lip and palate patients","volume":"102","author":"Baek","year":"2006","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"}],"container-title":["Annals of Maxillofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ams.ams_116_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:53:11Z","timestamp":1786647191000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ams.ams_116_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/ams.ams_116_25","relation":{},"ISSN":["2231-0746","2249-3816"],"issn-type":[{"value":"2231-0746","type":"print"},{"value":"2249-3816","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-06-24","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-25","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}