{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:50:01Z","timestamp":1787071801013,"version":"build-2736575974"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Rationale:<\/jats:title>\n                    <jats:p>This is a case of metastatic leiomyosarcoma (LMS) lesion of the condyle arising from a primary LMS of the uterus in a 43-year-old woman.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patient Concern:<\/jats:title>\n                    <jats:p>The patient presented an uncommon clinical manifestation not justified by the presence of a leiomyoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Diagnosis:<\/jats:title>\n                    <jats:p>The diagnostic process revealed that the patient was affected by uterine LMS, previously misdiagnosed as a leiomyoma, with a secondary metastasis of the left temporomandibular joint condyle.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Treatment:<\/jats:title>\n                    <jats:p>Surgery was proposed with total excision of the lesion and parotidectomy, together with radiotherapy and chemotherapy as adjuvant therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcome:<\/jats:title>\n                    <jats:p>One month after the start of the treatment, the systemic condition of the patient started to quickly worsen, and she passed away due to complications associated with the disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Take-away Lessons:<\/jats:title>\n                    <jats:p>Given the uncommon clinical scenario that the patient presented, guidelines for temporomandibular disorder should also include better indications on how to screen and intercept such possible life-threatening conditions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ams.ams_179_24","type":"journal-article","created":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T17:00:09Z","timestamp":1765472409000},"page":"252-255","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Misdiagnosed Uterine Leiomyosarcoma with Metastasis to the Left Condylar Neck - A Case Report"],"prefix":"10.4103","volume":"15","author":[{"given":"Ovidiu Ionut","family":"Saracutu","sequence":"first","affiliation":[{"name":"Department of Medical Biotechnologies, School of Dentistry University of Siena, Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Guarda-Nardini","sequence":"additional","affiliation":[{"name":"Unit of Oral and Maxillofacial Surgery, Ca Foncello Hospital, Treviso, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Ferrari","sequence":"additional","affiliation":[{"name":"Department of Medical Biotechnologies, School of Dentistry University of Siena, Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele","family":"Manfredini","sequence":"additional","affiliation":[{"name":"Department of Medical Biotechnologies, School of Dentistry University of Siena, Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Val","sequence":"additional","affiliation":[{"name":"Department of Medical Biotechnologies, School of Dentistry University of Siena, Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,12,11]]},"reference":[{"key":"R1-20260127","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.soc.2022.03.011","article-title":"Leiomyosarcoma: Current clinical management and future horizons","volume":"31","author":"Devaud","year":"2022","journal-title":"Surg Oncol Clin N Am"},{"key":"R3-20260127","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1186\/s12885-020-07425-9","article-title":"Malignant tumours of temporomandibular joint","volume":"20","author":"Yibulayin","year":"2020","journal-title":"BMC Cancer"},{"key":"R5-20260127","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/08869634.2024.2405298","article-title":"Temporomandibular disorders: INfORM\/IADR key points for good clinical practice based on standard of care","volume":"43","author":"Manfredini","year":"2024","journal-title":"CRANIO\u00ae"},{"key":"R6-20260127","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/j.bjoms.2018.07.013","article-title":"Solid malignant metastases in the jaw bones","volume":"56","author":"Andabak Rogulj","year":"2018","journal-title":"Br J Oral Maxillofac Surg"},{"key":"R7-20260127","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.oraloncology.2007.09.012","article-title":"Metastatic tumours to the oral cavity \u2013 Pathogenesis and analysis of 673 cases","volume":"44","author":"Hirshberg","year":"2008","journal-title":"Oral Oncol"},{"key":"R8-20260127","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1111\/joor.12132","article-title":"Expanding the taxonomy of the diagnostic criteria for temporomandibular disorders","volume":"41","author":"Peck","year":"2014","journal-title":"J Oral Rehabil"},{"key":"R9-20260127","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.ygyno.2017.02.012","article-title":"Prognosis and treatment of uterine leiomyosarcoma: A national cancer database study","volume":"145","author":"Seagle","year":"2017","journal-title":"Gynecol Oncol"},{"key":"R10-20260127","doi-asserted-by":"crossref","first-page":"106693","DOI":"10.1016\/j.phrs.2023.106693","article-title":"Novel therapeutic strategies targeting UCP2 in uterine leiomyosarcoma","volume":"189","author":"Nagao","year":"2023","journal-title":"Pharmacol Res"}],"container-title":["Annals of Maxillofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ams.ams_179_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:56:08Z","timestamp":1787068568000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ams.ams_179_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":8,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/ams.ams_179_24","relation":{},"ISSN":["2231-0746","2249-3816"],"issn-type":[{"value":"2231-0746","type":"print"},{"value":"2249-3816","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"2024-09-28","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-09","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}