{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:32:04Z","timestamp":1787758324839,"version":"build-2784847793"},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,1]]},"abstract":"\n Rationale<\/jats:title>\n Various traumatic risk factors have been correlated to the development of medication-related osteonecrosis of the jaw (MRONJ), with long-term use of antiresorptive or antiangiogenic medications. No previous cases of MRONJ secondary to endotracheal intubation have been reported in the oral and maxillofacial surgery literature.<\/jats:p>\n <\/jats:sec>\n \n Patient Concerns<\/jats:title>\n This case report describes a patient on long-term oral bisphosphonate therapy who presented with a nonhealing ulcer and exposed bony island along her right mandibular torus after undergoing general anaesthesia.<\/jats:p>\n <\/jats:sec>\n \n Diagnosis<\/jats:title>\n The lesion was diagnosed to be MRONJ secondary to pressure necrosis from postendotracheal intubation. These findings are suggested to be the result of poor control of the endotracheal tube while managing the airway.<\/jats:p>\n <\/jats:sec>\n \n Treatment and Outcomes<\/jats:title>\n After treatment with antibiotics and mouth rinses, the necrotic bone spontaneously dislodged with complete mucosalisation of the exposed site within 2 weeks.<\/jats:p>\n <\/jats:sec>\n \n Take-away Lessons<\/jats:title>\n Given the severe impact of MRONJ, it is imperative to recognise and minimise all controllable risk factors associated with its development.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ams.ams_300_21","type":"journal-article","created":{"date-parts":[[2022,8,17]],"date-time":"2022-08-17T14:33:58Z","timestamp":1660746838000},"page":"99-101","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["The Role of Endotracheal Tube in Medication-Related Osteonecrosis of the Jaw - A Case Report"],"prefix":"10.4103","volume":"12","author":[{"given":"Injamamul L.","family":"Niloy","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Walter Reed National Military Medical Center, Bethesda, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason N.","family":"Burkes","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Walter Reed National Military Medical Center, Bethesda, MD, USA"},{"name":"Department of Surgery, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,8,16]]},"reference":[{"key":"B1-20240828","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1016\/j.joms.2014.04.031","article-title":"American Association of Oral and Maxillofacial Surgeons position paper on medication-related osteonecrosis of the jaw-2014 update","volume":"72","author":"Ruggiero","year":"2014","journal-title":"J Oral Maxillofac Surg"},{"key":"B2-20240828","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1213\/ANE.0b013e3181e0cdcd","article-title":"Case report:Osteonecrosis of the mandible after laryngoscopy and endotracheal tube placement","volume":"111","author":"Almazrooa","year":"2010","journal-title":"Anesth Analg"},{"key":"B3-20240828","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.ctrv.2018.06.007","article-title":"Medication-related osteonecrosis of the jaw:Prevention, diagnosis and management in patients with cancer and bone metastases","volume":"69","author":"Otto","year":"2018","journal-title":"Cancer Treat Rev"},{"key":"B4-20240828","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.job.2019.03.005","article-title":"Medication-related osteonecrosis of the jaw:A literature review","volume":"61","author":"Kuroshima","year":"2019","journal-title":"J Oral Biosci"},{"key":"B5-20240828","first-page":"1158","article-title":"Bisphosphonate-related osteonecrosis of the jaw:Is pH the missing part in the pathogenesis puzzle?J Oral Maxillofac Surg","volume":"68","author":"Otto","year":"2010"},{"key":"B6-20240828","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.oooo.2019.08.004","article-title":"Systematic review of the use of pentoxifylline and tocopherol for the treatment of medication-related osteonecrosis of the jaw","volume":"128","author":"Heifetz-Li","year":"2019","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"}],"container-title":["Annals of Maxillofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ams.ams_300_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:10:03Z","timestamp":1787757003000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ams.ams_300_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":6,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/ams.ams_300_21","relation":{},"ISSN":["2231-0746","2249-3816"],"issn-type":[{"value":"2231-0746","type":"print"},{"value":"2249-3816","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"2021-12-25","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-22","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}