{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:31:52Z","timestamp":1787776312842,"version":"build-2784847793"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Surgical extraction of impacted third molars is a common procedure in maxillofacial surgery. Wound closure is typically achieved using knotted sutures, which require time and may lead to knot-related complications. Knotless sutures, widely used in various surgical fields, offer potential benefits for intraoral applications. This study evaluated the clinical utility of knotless sutures following third molar surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A randomised split-mouth clinical study was conducted on 29 patients undergoing bilateral mandibular third molar removal. Each patient received two types of sutures: knotless polyglyconate barbed sutures and control group: knotted polyglactin 910 sutures. Parameters assessed included suturing time, pain and discomfort during suturing (via Visual Analogue Scale) and post-operative outcomes on day 7, soft tissue healing (Modified Landry Index), wound dehiscence, facial swelling and maximum interincisal opening.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The knotless group showed significantly reduced suturing time and lower pain and discomfort scores. Improved soft tissue healing and reduced wound dehiscence were observed compared to the control group. No significant difference was found in facial swelling or mouth opening between the groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Knotless sutures are effective for intraoral wound closure after third molar extraction. They reduce operative time, minimise patient discomfort and enhance wound healing, offering a viable alternative to conventional knotted sutures.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ams.ams_3_25","type":"journal-article","created":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T13:00:12Z","timestamp":1754571612000},"page":"155-158","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Knotless Suture for Primary Wound Closure Following Surgical Removal of Impacted Mandibular Third Molars \u2013 A Comparative Study"],"prefix":"10.4103","volume":"15","author":[{"given":"Aayushi Nimishbhai","family":"Vora","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Ahmedabad Dental College and Hospital, Gandhinagar, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neha","family":"Vyas","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Ahmedabad Dental College and Hospital, Gandhinagar, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nitu","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Dharmsinh Desai University, Nadiad, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darshan","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Ahmedabad Dental College and Hospital, Gandhinagar, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prashant","family":"Malik","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Ahmedabad Dental College and Hospital, Gandhinagar, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akansha","family":"Bhatia","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Ahmedabad Dental College and Hospital, Gandhinagar, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,8,7]]},"reference":[{"key":"R1-20260127","doi-asserted-by":"crossref","first-page":"229","DOI":"10.4103\/2141-9248.160177","article-title":"Impacted mandibular third molars: Review of literature and a proposal of a combined clinical and radiological classification","volume":"5","author":"Santosh","year":"2015","journal-title":"Ann Med Health Sci Res"},{"key":"R2-20260127","doi-asserted-by":"crossref","first-page":"e72","DOI":"10.1016\/j.bjoms.2020.08.015","article-title":"Use of knotless barbed sutures for closure of intraoral incisions for maxillofacial trauma: A randomised controlled trial","volume":"59","author":"Sharma","year":"2021","journal-title":"Br J Oral Maxillofac Surg"},{"key":"R3-20260127","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jsurg.2010.09.015","article-title":"Bacterial adherence to suture materials","volume":"68","author":"Masini","year":"2011","journal-title":"J Surg Educ"},{"key":"R4-20260127","doi-asserted-by":"crossref","first-page":"161","DOI":"10.23736\/S2724-6329.23.04764-2","article-title":"Clinical and microbiological comparison of knotless\/barbed and silk sutures for impacted third-molar surgery","volume":"72","author":"Uysal","year":"2023","journal-title":"Minerva Dent Oral Sci"},{"key":"R5-20260127","doi-asserted-by":"crossref","first-page":"1954.e1","DOI":"10.1016\/j.joms.2018.03.017","article-title":"Knotless suture for wound closure in intraoral surgery-a report of 2 cases","volume":"76","author":"Kasi Ganesh","year":"2018","journal-title":"J Oral Maxillofac Surg"},{"key":"R6-20260127","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s12306-020-00654-y","article-title":"Barbed sutures reduce arthrotomy closure duration compared to interrupted conventional sutures for total knee arthroplasty: A randomized controlled trial","volume":"105","author":"Sundaram","year":"2021","journal-title":"Musculoskelet Surg"},{"key":"R7-20260127","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s12894-018-0435-3","article-title":"The application of barbed suture during the partial nephrectomy may modify perioperative results: A systematic review and meta-analysis","volume":"19","author":"Lin","year":"2019","journal-title":"BMC Urol"},{"key":"R8-20260127","first-page":"198","article-title":"Measuring techniques and clinical testing of an anti-inflammatory agent (tantum)","volume":"113","author":"Gabka","year":"1971","journal-title":"Munch Med Wochenschr"},{"key":"R9-20260127","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s12663-023-02000-8","article-title":"Does unidirectional polyglycolide caprolactone barbed suture have improved outcomes over non-barbed suture when applied for intra-oral incision closure?","volume":"23","author":"Deo","year":"2024","journal-title":"J Maxillofac Oral Surg"},{"key":"R10-20260127","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1016\/j.jobcr.2023.08.008","article-title":"Knotless barbed suture versus conventional polydioxanone suture material for intraoral surgical incisions \u2013 A randomized controlled trial","volume":"13","author":"Idupulapati","year":"2023","journal-title":"J Oral Biol Craniofac Res"},{"key":"R11-20260127","doi-asserted-by":"crossref","first-page":"308","DOI":"10.14639\/0392-100X-2130","article-title":"Barbed suture in oral cavity reconstruction: Preliminary results","volume":"39","author":"Crosetti","year":"2019","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"R12-20260127","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1016\/j.jcms.2020.07.014","article-title":"Effectiveness of knotless suture as a wound closure agent for impacted third molar \u2013 A split mouth randomized controlled clinical trial","volume":"48","author":"Ramkumar Ceyar","year":"2020","journal-title":"J Craniomaxillofac Surg"},{"key":"R13-20260127","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/j.eururo.2010.07.021","article-title":"Randomized controlled trial of barbed polyglyconate versus polyglactin suture for robot-assisted laparoscopic prostatectomy anastomosis: Technique and outcomes","volume":"58","author":"Williams","year":"2010","journal-title":"Eur Urol"},{"key":"R14-20260127","doi-asserted-by":"crossref","first-page":"395","DOI":"10.53730\/ijhs.v5nS2.5862","article-title":"Effectiveness of knotless barbed sutures as an intraoral wound closure agent in oral and maxillofacial surgery: A systematic review","volume":"5","author":"Krishnan","year":"2021","journal-title":"Int J Health Sci"},{"key":"R15-20260127","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1097\/DSS.0000000000001642","article-title":"Clinical evaluations of a novel thread lifting regimen using barbed polyglyconate suture for facial rejuvenation: Analysis using a 3-dimensional imaging system","volume":"45","author":"Kwon","year":"2019","journal-title":"Dermatol Surg"}],"container-title":["Annals of Maxillofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ams.ams_3_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:06:25Z","timestamp":1787774785000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ams.ams_3_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/ams.ams_3_25","relation":{},"ISSN":["2231-0746","2249-3816"],"issn-type":[{"value":"2231-0746","type":"print"},{"value":"2249-3816","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"2025-01-06","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-19","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}