{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:21:41Z","timestamp":1787775701339,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,7]]},"abstract":"Abstract<\/jats:title>\n \n Rationale:<\/jats:title>\n The aim of this study is to raise awareness among dentists regarding a potential outcome associated with the rapid growth of facial swellings.<\/jats:p>\n <\/jats:sec>\n \n Patient Concerns:<\/jats:title>\n We present a case of Ewing\u2019s sarcoma (ES) in a 23-year-old male who presented with a rapidly progressive swelling in the left maxillary region over six weeks.<\/jats:p>\n <\/jats:sec>\n \n Diagnosis:<\/jats:title>\n There was no significant intraoral dental finding other than a missing left upper first molar. Panoramic imaging initially suggested chronic sinusitis, but the swelling persisted despite treatment. A subsequent cone-beam computed tomography (CBCT) scan revealed a soft-tissue tumour affecting multiple sinuses, confirmed by an open biopsy as a small round cell tumour. Immunohistochemistry was used for precise diagnosis due to biopsy sample limitations and tumour variability.<\/jats:p>\n <\/jats:sec>\n \n Treatment:<\/jats:title>\n The patient\u2019s case was reviewed by our institution\u2019s tumour board. One month after diagnosis, chemotherapy began with alternating drugs for a total of 6 cycles.<\/jats:p>\n <\/jats:sec>\n \n Outcomes:<\/jats:title>\n A follow-up Positron Emission Tomography (PET)\/Computed Tomography (CT) scan after two months of chemotherapy showed resolution of the hypermetabolic mass on the left side without evidence of metastatic disease. The patient is currently under regular follow-up.<\/jats:p>\n <\/jats:sec>\n \n Take-Away Lessons:<\/jats:title>\n Dentists should be vigilant for rapidly expanding oral or facial swellings. Early and accurate diagnosis can improve clinical management and survival rates for ES patients.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ams.ams_49_24","type":"journal-article","created":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T10:16:27Z","timestamp":1725963387000},"page":"228-231","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Ewing\u2019s Sarcoma Presenting in the Paranasal Sinus \u2013 A Case Report"],"prefix":"10.4103","volume":"14","author":[{"given":"Yashika","family":"Kewalramani","sequence":"first","affiliation":[{"name":"Department of Oral Medicine and Radiology, Government College of Dentistry, Indore, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay","family":"Parihar","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Government College of Dentistry, Indore, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prashanthi","family":"Reddy","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Government College of Dentistry, Indore, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rashi","family":"Mandlik","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Government College of Dentistry, Indore, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,9,9]]},"reference":[{"key":"R1-20250109","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1016\/j.hoc.2013.07.001","article-title":"Update in treatment and targets in Ewing sarcoma","volume":"27","author":"Cote","year":"2013","journal-title":"Hematol Oncol Clin North Am"},{"key":"R2-20250109","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1016\/S0031-3955(05)70541-1","article-title":"The Ewing family of tumors. Ewing's sarcoma and primitive neuroectodermal tumors","volume":"44","author":"Grier","year":"1997","journal-title":"Pediatr Clin North Am"},{"key":"R3-20250109","doi-asserted-by":"crossref","first-page":"66","DOI":"10.4132\/jptm.2014.10.14","article-title":"Ewing's sarcoma\/primitive neuroectodermal tumor of the uterine corpus","volume":"49","author":"Lee","year":"2015","journal-title":"J Pathol Transl Med"},{"key":"R4-20250109","doi-asserted-by":"crossref","first-page":"257","DOI":"10.4132\/jptm.2015.04.14","article-title":"IDH mutation analysis in Ewing sarcoma family tumors","volume":"49","author":"Na","year":"2015","journal-title":"J Pathol Transl Med"},{"key":"R5-20250109","doi-asserted-by":"crossref","first-page":"470","DOI":"10.5005\/jp-journals-10005-1665","article-title":"Ewing's sarcoma of mandible: A case report with review","volume":"12","author":"Ahuja","year":"2019","journal-title":"Int J Clin Pediatr Dent"},{"key":"R6-20250109","doi-asserted-by":"crossref","first-page":"e232460","DOI":"10.1136\/bcr-2019-232460","article-title":"Extra-skeletal Ewing's sarcoma of the frontal sinus: A rare disorder in pediatric age","volume":"13","author":"Costa","year":"2020","journal-title":"BMJ Case Rep"},{"key":"R7-20250109","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.humpath.2016.05.008","article-title":"Ewing sarcoma: A chronicle of molecular pathogenesis","volume":"55","author":"Kim","year":"2016","journal-title":"Hum Pathol"},{"key":"R8-20250109","doi-asserted-by":"crossref","first-page":"2829","DOI":"10.1002\/1097-0142(19871201)60:11<2829::AID-CNCR2820601139>3.0.CO;2-S","article-title":"Primary Ewing's sarcoma involving the bones of the head and neck","volume":"60","author":"Siegal","year":"1987","journal-title":"Cancer"},{"key":"R9-20250109","doi-asserted-by":"crossref","first-page":"811","DOI":"10.3171\/jns.1979.50.6.0811","article-title":"Localized primary intracranial Ewing's sarcoma of the orbital roof: Case report","volume":"50","author":"Alvarez-Berdecia","year":"1979","journal-title":"J Neurosurg"},{"key":"R10-20250109","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.jclinepi.2017.04.026","article-title":"CARE guidelines for case reports: Explanation and elaboration document","volume":"89","author":"Riley","year":"2017","journal-title":"J Clin Epidemiol"}],"container-title":["Annals of Maxillofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ams.ams_49_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:39:38Z","timestamp":1787773178000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ams.ams_49_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/ams.ams_49_24","relation":{},"ISSN":["2231-0746","2249-3816"],"issn-type":[{"value":"2231-0746","type":"print"},{"value":"2249-3816","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"2024-03-21","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-02","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}