{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:31:43Z","timestamp":1787776303764,"version":"build-2784847793"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Reversible cerebral vasoconstriction syndrome (RCVS) is generally recognized as an intracranial pathology. Involvement of the extracranial segments of the carotid or vertebral arteries (VAs) is rare. Here, we present a case of postpartum RCVS with extracranial VA involvement. A 31-year-old female developed postpartum thunderclap headaches with neck pain, followed by generalized seizures. The patient had been healthy with an uncomplicated pregnancy and delivery. Head computed tomography showed minimal right frontal convexity subarachnoid hemorrhage. Transcranial color-coded sonography disclosed increased mean flow velocity in multiple arteries, consistent with vasoconstriction, while the extracranial Doppler study revealed an abrupt change in the diameter of the left VA, indicative of dissection or vasospasm. Brain magnetic resonance imaging demonstrated nonenhancing T2\/fluid-attenuated inversion recovery hyperintensities involving bilateral occipital, parietal, and frontal regions, with normal diffusion-weighted imaging signals, suggesting vasogenic edema. Magnetic resonance angiography showed multifocal segmental vasoconstriction of cerebral arteries, along with multiple irregular luminal narrowing of bilateral extracranial VAs. T1 fat-suppressed images revealed no features indicative of arterial dissection. The patient was treated with nimodipine as she was diagnosed with postpartum RCVS with extracranial artery involvement and concomitant posterior reversible encephalopathy syndrome. During an outpatient follow-up 1 month after discharge, she reported complete resolution of symptoms. It is crucial to acknowledge that cervical artery vasoconstriction, while rare, remains a possibility in RCVS. In patients having significant multiple extracranial artery vasoconstriction, even when they are the main or even the only arteries involved, RCVS should always be taken into consideration.<\/jats:p>","DOI":"10.4103\/ant.ant_113_0025","type":"journal-article","created":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T13:00:10Z","timestamp":1748437210000},"page":"102-105","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["A Case of Postpartum Reversible Cerebral Vasoconstriction Syndrome with Extracranial Artery Involvement"],"prefix":"10.4103","volume":"34","author":[{"given":"Yu-Jyun","family":"Hong","sequence":"first","affiliation":[{"name":"Department of Neurology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han-Cheng","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan"},{"name":"Department of Neurology, College of Medicine, National Taiwan University, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,5,28]]},"reference":[{"key":"R1-20250613","doi-asserted-by":"crossref","first-page":"e248","DOI":"10.1212\/WNL.0000000000012223","article-title":"Reversible cerebral vasoconstriction syndrome:Symptoms, incidence, and resource utilization in a population-based US cohort","volume":"97","author":"Magid-Bernstein","year":"2021","journal-title":"Neurology"},{"key":"R2-20250613","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1177\/2396987316656981","article-title":"Gender and hormonal influences in reversible cerebral vasoconstriction syndrome","volume":"1","author":"Topcuoglu","year":"2016","journal-title":"Eur Stroke J"},{"key":"R3-20250613","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/S1474-4422(12)70135-7","article-title":"Reversible cerebral vasoconstriction syndrome","volume":"11","author":"Ducros","year":"2012","journal-title":"Lancet Neurol"},{"key":"R4-20250613","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1001\/archneurol.2011.68","article-title":"Reversible cerebral vasoconstriction syndromes:Analysis of 139 cases","volume":"68","author":"Singhal","year":"2011","journal-title":"Arch Neurol"},{"key":"R5-20250613","doi-asserted-by":"crossref","first-page":"222","DOI":"10.4103\/bc.bc_58_22","article-title":"Extracranial reversible cerebral vasoconstriction syndrome associated with vertebral artery dissection:A case report","volume":"8","author":"Yoon","year":"2022","journal-title":"Brain Circ"},{"key":"R6-20250613","doi-asserted-by":"crossref","first-page":"488","DOI":"10.3390\/neurolint14020040","article-title":"Reversible cerebral vasoconstriction syndrome in the postpartum period:A systematic review and meta-analysis","volume":"14","author":"Pacheco","year":"2022","journal-title":"Neurol Int"},{"key":"R7-20250613","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1177\/1358863X14567976","article-title":"Postpartum reversible cerebral vasoconstriction syndrome:Review and analysis of the current data","volume":"20","author":"Skeik","year":"2015","journal-title":"Vasc Med"},{"key":"R8-20250613","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.bjae.2021.12.004","article-title":"Postpartum headache \u2013Diagnosis and treatment","volume":"22","author":"Janvier","year":"2022","journal-title":"BJA Educ"},{"key":"R9-20250613","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1007\/s11916-010-0106-x","article-title":"Reversible cerebral vasospasm, multilobular intracerebral hemorrhages, and nonaneurysmal subarachnoid hemorrhage:Review of possible interrelationships","volume":"14","author":"Hantson","year":"2010","journal-title":"Curr Pain Headache Rep"},{"key":"R10-20250613","doi-asserted-by":"crossref","first-page":"419","DOI":"10.3340\/jkns.2014.56.5.419","article-title":"Progressive manifestations of reversible cerebral vasoconstriction syndrome presenting with subarachnoid hemorrhage, intracerebral hemorrhage, and cerebral infarction","volume":"56","author":"Choi","year":"2014","journal-title":"J Korean Neurosurg Soc"},{"key":"R11-20250613","doi-asserted-by":"crossref","first-page":"34","DOI":"10.3389\/fneur.2020.00034","article-title":"Posterior reversible encephalopathy syndrome and reversible cerebral vasoconstriction syndrome:Clinical and radiological considerations","volume":"11","author":"Pilato","year":"2020","journal-title":"Front Neurol"},{"key":"R12-20250613","doi-asserted-by":"crossref","first-page":"3091","DOI":"10.1093\/brain\/awm256","article-title":"The clinical and radiological spectrum of reversible cerebral vasoconstriction syndrome. A prospective series of 67 patients","volume":"130","author":"Ducros","year":"2007","journal-title":"Brain"},{"key":"R13-20250613","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1212\/WNL.0b013e3182a2cbe2","article-title":"Reversible cerebral vasoconstriction syndrome and cervical artery dissection in 20 patients","volume":"81","author":"Mawet","year":"2013","journal-title":"Neurology"},{"key":"R14-20250613","first-page":"45","article-title":"Isolated extracranial vasospasm and intracranial dissection:An unusual imaging manifestation of reversible cerebral vasoconstriction syndrome","volume":"9","author":"Al Zahmi","year":"2017","journal-title":"J Vasc Interv Neurol"},{"key":"R15-20250613","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s00062-014-0335-1","article-title":"Diffuse intracranial and extracranial vascular involvement in reversible cerebral vasoconstriction syndrome","volume":"25","author":"Kushkuley","year":"2015","journal-title":"Clin Neuroradiol"}],"container-title":["Acta Neurologica Taiwanica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ANT.ANT_113_0025","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:08:16Z","timestamp":1787774896000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ANT.ANT_113_0025"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/ant.ant_113_0025","relation":{},"ISSN":["1028-768X"],"issn-type":[{"value":"1028-768X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"2024-03-28","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-29","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}