{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T16:23:01Z","timestamp":1787847781551,"version":"build-2784847793"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Patients with single ventricle physiology who have undergone the Fontan procedure are at risk for long-term complications such as thrombus formation. Thrombus formation in the native aortic root (NAR) can be life-threatening if retrograde filling of the coronary arteries (CAs) is impaired. We present three cases of NAR thrombus with embolization to the CA, resulting in myocardial infarction. Thromboembolic events are well-documented complications of Fontan physiology, and optimal prevention and treatment strategies are poorly defined.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/apc.apc_103_20","type":"journal-article","created":{"date-parts":[[2021,1,18]],"date-time":"2021-01-18T13:44:11Z","timestamp":1610977451000},"page":"72-74","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Myocardial infarction due to thrombosis of native aorta late after Fontan procedure for hypoplastic left heart syndrome"],"prefix":"10.4103","volume":"14","author":[{"given":"Bhavi","family":"Patel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tacy","family":"Downing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lourdes","family":"Prieto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darline","family":"Santana-Acosta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-10-20240901","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1177\/1076029613520464","article-title":"Thrombosis and thromboembolic complications in Fontan patients: A literature review","volume":"20","author":"Firdouse","year":"2014","journal-title":"Clin Appl Thromb Hemost"},{"key":"R2-10-20240901","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1016\/j.amjcard.2017.03.004","article-title":"Effects of Fontan-associated morbidities on survival with intact Fontan circulation","volume":"119","author":"Allen","year":"2017","journal-title":"Am J Cardiol"},{"key":"R3-10-20240901","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.jacc.2012.08.1023","article-title":"Factors associated with thrombotic complications after the Fontan procedure: A secondary analysis of a multicenter, randomized trial of primary thromboprophylaxis for 2 years after the Fontan procedure","volume":"61","author":"McCrindle","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"R4-10-20240901","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1111\/j.1747-0803.2008.00217.x","article-title":"Antiphospholipid syndrome leading to myocardial infarction in a Fontan patient 17 years after Norwood palliation","volume":"4","author":"Morchi","year":"2009","journal-title":"Congenit Heart Dis"},{"key":"R5-10-20240901","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1017\/S1047951107000340","article-title":"Formation of thrombus in a native aortic sinus of Valsalva after palliation of hypoplastic left heart syndrome","volume":"17","author":"Mookerjee","year":"2007","journal-title":"Cardiol Young"},{"key":"R6-10-20240901","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1093\/icvts\/ivv123","article-title":"Aortic root thrombosis with coronary embolization following neo-aortic reconstruction in a child with hypoplastic left heart syndrome","volume":"21","author":"Mitchell","year":"2015","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"R7-10-20240901","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1007\/s00246-005-1274-z","article-title":"Thrombus formation in the native aortic root in patients with hypoplastic left heart syndrome","volume":"27","author":"Owens","year":"2006","journal-title":"Pediatr Cardiol"},{"key":"R8-10-20240901","doi-asserted-by":"crossref","first-page":"e29","DOI":"10.1016\/j.athoracsur.2006.07.068","article-title":"Neoaortic root modification for late thrombosis after Norwood palliation","volume":"82","author":"Graham","year":"2006","journal-title":"Ann Thorac Surg"},{"key":"R9-10-20240901","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1016\/S0003-4975(97)01041-2","article-title":"Causes of death after the modified Norwood procedure: A study of 122 postmortem cases","volume":"64","author":"Bartram","year":"1997","journal-title":"Ann Thorac Surg"}],"container-title":["Annals of Pediatric Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/apc.APC_103_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:37:39Z","timestamp":1787845059000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/apc.APC_103_20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/apc.apc_103_20","relation":{},"ISSN":["0974-2069"],"issn-type":[{"value":"0974-2069","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]}}}