{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T17:05:41Z","timestamp":1787504741630,"version":"build-2736575974"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The long-term structural integrity of expanded polytetrafluoroethylene (ePTFE) conduits used for extracardiac total cavopulmonary connection (EC-TCPC) is not well established. Although conduit calcification has been reported, quantitative data remain limited. We retrospectively analyzed 20 EC-TCPC patients who underwent computed tomography more than 5 years after Fontan completion (median: 13.7 years). Cross-sectional area (CSA) was measured at five sites and expressed as a percentage of the original CSA (%CSA), and calcification volume was indexed to body surface area. Median values of mean and minimum %CSA were 74.0% and 65.5%, respectively. %CSA correlated inversely with calcification volume index (\u03c1 = \u22120.47,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = 0.04). Calcification was greater along the lesser curvature than the greater curvature (0.66 vs. 0.20 mm\n                    <jats:sup>3<\/jats:sup>\n                    \/m\n                    <jats:sup>2<\/jats:sup>\n                    ,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; 0.001). These findings suggest curvature-specific vulnerability in ePTFE conduits and support the importance of long-term structural surveillance in Fontan patients.\n                  <\/jats:p>","DOI":"10.4103\/apc.apc_114_26","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T05:00:15Z","timestamp":1779771615000},"page":"193-197","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Asymmetric calcification of the extracardiac Fontan conduit: Quantitative insights from long-term computed tomography imaging"],"prefix":"10.4103","volume":"19","author":[{"given":"Yuchen","family":"Cao","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, Seirei Hamamatsu General Hospital, Hamamatsu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaaki","family":"Koide","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Seirei Hamamatsu General Hospital, Hamamatsu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masafumi","family":"Yashima","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Seirei Hamamatsu General Hospital, Hamamatsu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aya","family":"Miyazaki","sequence":"additional","affiliation":[{"name":"Department of Adult Congenital Heart Disease, Seirei Hamamatsu General Hospital, Hamamatsu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,5,25]]},"reference":[{"key":"R1-20260527","first-page":"100505","article-title":"Long-term outcomes of extracardiac gore-tex conduits in Fontan patients","volume":"16","author":"Lee","year":"2024","journal-title":"Int J Cardiol Congenit Heart 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Cardiol"},{"key":"R8-20260527","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/bmt.2012.244","article-title":"Investigation of the freely available easy-to-use software 'EZR' for medical statistics","volume":"48","author":"Kanda","year":"2013","journal-title":"Bone Marrow Transplant"},{"key":"R9-20260527","first-page":"1059","article-title":"Stent expansion of restrictive Fontan conduits to nominal diameter and beyond","volume":"100","author":"Salaets","year":"2022","journal-title":"Catheter Cardiovasc Interv"},{"key":"R10-20260527","first-page":"1134","article-title":"Transcatheter stenting to restore cross-sectional area of extracardiac Fontan conduits","volume":"105","author":"Patel","year":"2025","journal-title":"Catheter Cardiovasc Interv"},{"key":"R11-20260527","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1007\/s00246-020-02452-6","article-title":"Evaluating the longevity of the Fontan pathway","volume":"41","author":"Kelly","year":"2020","journal-title":"Pediatr Cardiol"},{"key":"R12-20260527","doi-asserted-by":"crossref","first-page":"914609","DOI":"10.3389\/fcvm.2022.914609","article-title":"Outcomes of treatment for right atrial isomerism with functional single ventricle and extracardiac total anomalous pulmonary venous connection beyond neonatal period: Delayed surgical treatment, improving outcomes","volume":"9","author":"Chen","year":"2022","journal-title":"Front Cardiovasc Med"}],"container-title":["Annals of Pediatric Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/apc.apc_114_26","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:31:44Z","timestamp":1786735904000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/apc.apc_114_26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/apc.apc_114_26","relation":{},"ISSN":["0974-2069","0974-5149"],"issn-type":[{"value":"0974-2069","type":"print"},{"value":"0974-5149","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"2026-03-19","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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