{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T15:11:51Z","timestamp":1788966711679,"version":"build-2803163510"},"reference-count":48,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Arrhythmias remain a major clinical challenge in adult congenital heart disease (aCHD), contributing significantly to increased hospitalization rates and cardiac complications, affecting over 50% of aCHD patients. Catheter ablation (CA) is regarded as a first-line therapeutic modality due to its potential for disease modification. However, concerns persist regarding its long-term efficacy and safety. Thus, a comprehensive evaluation of CA outcomes in this population is warranted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The outcomes of interest were the success rate, secondary ablation rate, complication rates, and recurrence of arrhythmias. Quality assessment was done using the Risk of Bias in Non-randomized Studies of Interventions tool, and meta-analysis was performed using RStudio.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A comprehensive search of seven databases yielded 15 articles for analysis, among which 10 were categorized as low-risk, four as moderate-risk, and one lacked information regarding bias. The single-arm meta-analysis, examining events per 100 observations, revealed a success rate of 85.37 (95% confidence interval [CI] =78.50, 92.24). Moreover, the secondary ablation rate was determined to be 29.29 (95% CI = 16.92, 41.66), while major complications occurred at a rate of 2.81 (95% CI = 0.89, 4.73) and minor complications at a rate of 5.29 (95% CI = 1.88, 8.70). The overall recurrence rate of arrhythmias was found to be 40.33 (95% CI = 28.37, 52.29), with specific rates for intra-atrial reentrant tachycardia at 20.33 (95% CI = 11.24, 29.43), atrial fibrillation at 14.25 (95% CI = 3.46, 25.05), and atrioventricular nodal reentrant tachycardia at 9.70 (95% CI = 0.00, 19.56). Lastly, the implantation rate of implantable cardioverter defibrilators (ICDs) was found to be 1.05 (95% CI = 0.12, 1.99).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>CA for arrhythmias in aCHD patients demonstrates high success rates with minimal procedural complications. However, the substantial recurrence rates highlight the need for ongoing monitoring and proactive strategies to optimize long-term outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/apc.apc_134_25","type":"journal-article","created":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T10:21:22Z","timestamp":1788949282000},"page":"475-489","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy of catheter ablation for arrhythmia in adults with congenital heart disease: A meta-analysis of clinical outcomes"],"prefix":"10.4103","volume":"19","author":[{"given":"Imke Maria","family":"Puling","sequence":"first","affiliation":[{"name":"Clinical Clerkship Program, Faculty of Medicine, Universitas Brawijaya - Saiful Anwar Regional General Hospital, Malang, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Willyanto","sequence":"additional","affiliation":[{"name":"Clinical Clerkship Program, Faculty of Medicine, Universitas Brawijaya - Saiful Anwar Regional General Hospital, Malang, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nyoman Deva","family":"Giri","sequence":"additional","affiliation":[{"name":"Clinical Clerkship Program, Faculty of Medicine, Universitas Brawijaya - Saiful Anwar Regional General Hospital, Malang, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesphine Arbi","family":"Wijaya","sequence":"additional","affiliation":[{"name":"Clinical Clerkship Program, Faculty of Medicine, Universitas Brawijaya - Saiful Anwar Regional General Hospital, Malang, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liliana","family":"Dewi","sequence":"additional","affiliation":[{"name":"Clinical Clerkship Program, Faculty of Medicine, Universitas Brawijaya - Saiful Anwar Regional General Hospital, Malang, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derren DCH","family":"Rampengan","sequence":"additional","affiliation":[{"name":"Clinical Clerkship Program, Faculty of Medicine, Universitas Sam Ratulangi - R.D. Kandou Central General Hospital, Manado, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerinna Yogibuana Swastika","family":"Putri","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Vascular Medicine, Brawijaya Cardiovascular Research Center, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Starry Homenta","family":"Rampengan","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Vascular Medicine, Division of Interventional Cardiology, Faculty of Medicine, Universitas Sam Ratulangi - R.D. 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