{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:36:28Z","timestamp":1786649788430,"version":"build-2736575974"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>This study aimed to assess parental perceptions of quality of life in children aged 5\u201318 with simple and complex forms of repaired tetralogy of Fallot and its determinants, using an original survey including the Pediatric Quality of Life Inventory 4.0 (PedsQL 4.0) questionnaire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results:<\/jats:title>\n                    <jats:p>\n                      Data were gathered through an original online survey of repaired tetralogy of Fallot patients at a reference center for congenital heart disease. The survey, conducted between March and July 2023, included the PedsQL 4.0 (parental version), inquiries on extracurricular sports participation, sleep patterns, distance from the hospital, and social assessment. Of 74 contacts, 51 responses were obtained, representing children with an average age of 10.5 \u00b1 3.7 years. Parents perceived lower quality of life in these children compared to healthy Portuguese counterparts, both in physical (72% vs. 83.5%,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001) and psychosocial (73% vs. 78.2%,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.01) dimensions. Higher physical and psychosocial quality of life were associated with extracurricular sports practice (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.012 and\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.008, respectively), as well as with a greater number of hours spent in extracurricular sports (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.00001 and\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.01, respectively). Factors such as sleep patterns, distance from the hospital, socioeconomic status, and number of surgeries did not correlate with quality of life.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Portuguese children with repaired tetralogy of Fallot exhibit a lower quality of life than their healthy peers, as perceived by parents. Regular sports engagement is associated with improved quality of life, emphasizing the importance of assessing sports habits as an integral component of their follow-up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/apc.apc_208_24","type":"journal-article","created":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T17:04:59Z","timestamp":1759856699000},"page":"204-209","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["A comprehensive evaluation of quality of life and its determinants in portuguese pediatric patients with repaired tetralogy of fallot: An observational study"],"prefix":"10.4103","volume":"18","author":[{"given":"B\u00e1rbara De Paiva Mor\u00e3o Ribeiro","family":"De Aguiar","sequence":"first","affiliation":[{"name":"Department of Pediatric, Beatriz \u00c2ngelo Hospital, Loures, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Rita","family":"Constante","sequence":"additional","affiliation":[{"name":"Caldas da Rainha Hospital, Caldas da Rainha, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana Silva","family":"Costa","sequence":"additional","affiliation":[{"name":"Child and Youth Department, Hospital Professor Doutor, Fernando Fonseca, Amadora, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mafalda Jo\u00e3o","family":"Pereira","sequence":"additional","affiliation":[{"name":"Pediatric Department, Faro Hospital, Faro, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel Sampaio","family":"Gra\u00e7a","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology Department, Santa Cruz Hospital, Carnaxide, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miquel","family":"Verdaguer","sequence":"additional","affiliation":[{"name":"Department of Mathematics, Polytechnic University of Catalonia, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui T.","family":"Anjos","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology Department, Santa Cruz Hospital, Carnaxide, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o P.","family":"Rato","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology Department, Santa Cruz Hospital, Carnaxide, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,10,7]]},"reference":[{"key":"R1-20260420","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1186\/s12872-021-02157-5","article-title":"Validity and reliability of the Italian version of the cardiac quality of life questionnaire for pediatric patients with heart disease (PedsQLTM)","volume":"21","author":"Grimaldi Capitello","year":"2021","journal-title":"BMC Cardiovasc Disord"},{"key":"R3-20260420","doi-asserted-by":"crossref","first-page":"65","DOI":"10.4103\/ijpvm.IJPVM_429_17","article-title":"Quality of life in different chronic diseases and its related factors","volume":"10","author":"Samiei Siboni","year":"2019","journal-title":"Int J Prev Med"},{"key":"R4-20260420","doi-asserted-by":"crossref","first-page":"e27","DOI":"10.4081\/hpr.2013.e27","article-title":"Quality of life in chronic disease patients","volume":"1","author":"Megari","year":"2013","journal-title":"Health Psychol Res"},{"key":"R5-20260420","doi-asserted-by":"crossref","first-page":"4763","DOI":"10.1016\/j.sbspro.2010.03.765","article-title":"Quality of life of children with chronic illnesses: A review of the literature","volume":"2","author":"Kourkoutas","year":"2010","journal-title":"Procedia Soc Behav Sci"},{"key":"R6-20260420","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1161\/CIR.0b013e318293688f","article-title":"Promotion of physical activity for children and adults with congenital heart disease: A scientific statement from the American Heart Association","volume":"127","author":"Longmuir","year":"2013","journal-title":"Circulation"},{"key":"R7-20260420","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/1479-5868-7-40","article-title":"Systematic review of the health benefits of physical activity and fitness in school-aged children and youth","volume":"7","author":"Janssen","year":"2010","journal-title":"Int J Behav Nutr Phys Act"},{"key":"R8-20260420","doi-asserted-by":"crossref","first-page":"3073","DOI":"10.1093\/eurheartj\/ehq356","article-title":"Predictors of morbidity and mortality in contemporary Fontan patients: Results from a multicenter study including cardiopulmonary exercise testing in 321 patients","volume":"31","author":"Diller","year":"2010","journal-title":"Eur Heart J"},{"key":"R11-20260420","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1016\/j.jpeds.2005.01.055","article-title":"Evidence based physical activity for school-age youth","volume":"146","author":"Strong","year":"2005","journal-title":"J Pediatr"},{"key":"R12-20260420","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1007\/s00246-001-0054-7","article-title":"Exercise performance in tetralogy of Fallot: The impact of primary complete repair in infancy","volume":"23","author":"Mahle","year":"2002","journal-title":"Pediatr Cardiol"},{"key":"R13-20260420","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1016\/j.athoracsur.2005.09.010","article-title":"Long-term neurodevelopmental outcome and exercise capacity after corrective surgery for tetralogy of Fallot or ventricular septal defect in infancy","volume":"81","author":"H\u00f6vels-G\u00fcrich","year":"2006","journal-title":"Ann Thorac Surg"},{"key":"R14-20260420","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1161\/CIRCULATIONAHA.111.058719","article-title":"Comprehensive use of cardiopulmonary exercise testing identifies adults with congenital heart disease at increased mortality risk in the medium term","volume":"125","author":"Inuzuka","year":"2012","journal-title":"Circulation"},{"key":"R15-20260420","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1016\/j.jacc.2005.02.009","article-title":"Task force 2: Congenital heart disease","volume":"45","author":"Graham","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"R16-20260420","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1177\/1741826711420000","article-title":"Recommendations for physical activity, recreation sport, and exercise training in paediatric patients with congenital heart disease: A report from the exercise, basic and translational research section of the European Association of Cardiovascular Prevention and Rehabilitation, the European Congenital Heart and Lung Exercise Group, and the Association for European Paediatric Cardiology","volume":"19","author":"Takken","year":"2012","journal-title":"Eur J Prev Cardiol"},{"key":"R17-20260420","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1747-0803.2010.00481.x","article-title":"Children and adolescents with repaired tetralogy of Fallot report quality of life similar to healthy peers","volume":"6","author":"Kwon","year":"2011","journal-title":"Congenit Heart Dis"},{"key":"R18-20260420","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1186\/s12955-020-01615-6","article-title":"Health-related quality of life in children with congenital heart disease aged 5 to 7 years: A multicentre controlled cross-sectional study","volume":"18","author":"Abassi","year":"2020","journal-title":"Health Qual Life Outcomes"},{"key":"R19-20260420","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1007\/s00246-015-1201-x","article-title":"Quality of life of children with congenital heart diseases: A multicenter controlled cross-sectional study","volume":"36","author":"Amedro","year":"2015","journal-title":"Pediatr Cardiol"},{"key":"R20-20260420","doi-asserted-by":"crossref","first-page":"255","DOI":"10.4103\/2277-9175.170680","article-title":"Anxiety determinants in mothers of children with congenital heart diseases undergoing cardiac surgery","volume":"4","author":"Rahimianfar","year":"2015","journal-title":"Adv Biomed Res"},{"key":"R21-20260420","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1017\/S1047951117001378","article-title":"Multidisciplinary family-centred psychosocial care for patients with CHD: Consensus recommendations from the AEPC psychosocial working group","volume":"28","author":"Utens","year":"2018","journal-title":"Cardiol Young"},{"key":"R22-20260420","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1007\/s00246-006-0123-z","article-title":"Long-term behavior and quality of life after corrective cardiac surgery in infancy for tetralogy of Fallot or ventricular septal defect","volume":"28","author":"H\u00f6vels-G\u00fcrich","year":"2007","journal-title":"Pediatr Cardiol"},{"key":"R23-20260420","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.jesf.2023.05.002","article-title":"Results from Portugal\u2019s 2022 report card on physical activity for children and youth","volume":"21","author":"Pizarro","year":"2023","journal-title":"J Exerc Sci Fit"}],"container-title":["Annals of Pediatric Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/apc.apc_208_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:58:26Z","timestamp":1786647506000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/apc.apc_208_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/apc.apc_208_24","relation":{},"ISSN":["0974-2069","0974-5149"],"issn-type":[{"value":"0974-2069","type":"print"},{"value":"0974-5149","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"2024-10-31","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-01","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}