{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T04:44:52Z","timestamp":1787719492918,"version":"build-2784847793"},"reference-count":5,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>We report a 6-month-old female infant with deletion of chromosome 22q11.2 (DiGeorge\/VFS TUPLE 1), normal atrial arrangement with concordant atrioventricular connection, pulmonary atresia, large subaortic ventricular septal defect, diminutive native pulmonary arteries, a characteristic weird-shape right aortic arch with arch-on-arch appearance and figure of 8 configuration. We presented the cardiac computed tomographic angiographic and cardiac angiographic features. Using Autodesk 3ds Max 2018 software, we explained and illustrated the speculative embryologic etiology of this bizarre aortic archanomaly with the extensive abnormal remodeling of the left brachiocephalic artery, based on a \u201cfive-embryonic aortic arches\u201d concept. As to the best of the authors' knowledge, this is the first report of a genetically confirmed case of DiGeorge syndrome and an exceedingly rare type of right aortic arch anomaly with embryologic explanation according to the \u201cfive-embryonic-aortic-arches\u201d concept. It seems that the constellation of pulmonary atresia, bizarreshaped right aortic arch due to abnormal development of the aortic sac, and abnormal remodeling of the left brachiocephalic artery may be strongly suggestive of DiGeorge syndrome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/apc.apc_215_19","type":"journal-article","created":{"date-parts":[[2020,11,30]],"date-time":"2020-11-30T09:31:23Z","timestamp":1606728683000},"page":"125-127","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["DiGeorge syndrome and anomalous right aortic arch with arch-on-arch and figure-of-eight configurations"],"prefix":"10.4103","volume":"14","author":[{"given":"Elaheh","family":"Malakan Rad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Momtazmanesh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-25-20240901","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1017\/S1047951114002182","article-title":"How frequent is the fifth arch artery?","volume":"25","author":"Gupta","year":"2015","journal-title":"Cardiol Young"},{"key":"R3-25-20240901","doi-asserted-by":"crossref","first-page":"62","DOI":"10.4103\/0974-2069.171392","article-title":"Clarifying the anatomy of the fifth arch artery","volume":"9","author":"Gupta","year":"2016","journal-title":"Ann Pediatr Cardiol"},{"key":"R4-25-20240901","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1111\/joa.13067","article-title":"A reappraisal and revision of the numbering of the pharyngeal arches","volume":"235","author":"Graham","year":"2019","journal-title":"J Anat"},{"key":"R5-25-20240901","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/S0929-6646(09)60119-4","article-title":"Persistent fifth aortic arch associated with 22q11.2 deletion syndrome","volume":"105","author":"Lee","year":"2006","journal-title":"J Formos Med Assoc"},{"key":"R6-25-20240901","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1053\/j.jvca.2013.10.025","article-title":"Perioperative management of patients with DiGeorge syndrome undergoing cardiac surgery","volume":"28","author":"Yeoh","year":"2014","journal-title":"J Cardiothorac Vasc Anesth"}],"container-title":["Annals of Pediatric Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/apc.APC_215_19","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:30:17Z","timestamp":1786735817000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/apc.APC_215_19"}},"subtitle":["Aortic sac maldevelopment and left brachiocephalic artery abnormal remodeling"],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":5,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/apc.apc_215_19","relation":{},"ISSN":["0974-2069"],"issn-type":[{"value":"0974-2069","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]}}}