{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T12:58:28Z","timestamp":1785502708431,"version":"3.56.0"},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:p>Gorlin-Goltz syndrome (GGS) is a rare hereditary autosomal dominant condition. Cardiac fibromas are one of the clinical manifestations of this disease. The presence of these benign heart tumors may lead to life-threatening complications. We present the case of a 5-year-old girl with GGS and a large cardiac fibroma who had ventricular fibrillation during respiratory tract infection. Several options of treatment were considered in the secondary prevention of cardiac arrest. A partial resection of the tumor was performed to prevent recurrence of malignant arrhythmia. The loop recorder implanted postoperatively didn\u2019t record any episodes of sustained ventricular arrhythmia in a 9-month follow-up. In conclusion, cardiac fibromas, especially with the presence of infections, increase risk of ventricular arrhythmias. Partial resection of tumor can be effective and relatively safe in the secondary prevention of ventricular fibrillation in patients with large cardiac fibromas with GGS.<\/jats:p>","DOI":"10.4103\/apc.apc_82_26","type":"journal-article","created":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T11:00:14Z","timestamp":1785495614000},"page":"454-456","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Therapeutic challenge in a 5-year-old girl with Gorlin-Goltz syndrome and cardiac fibroma"],"prefix":"10.4103","volume":"19","author":[{"given":"Agnieszka","family":"Pskit-Hanuszczak","sequence":"first","affiliation":[{"name":"Department of Pediatric Cardiology and General Pediatrics, Doctoral School, Medical University of Warsaw, Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomasz","family":"Ksi\u0105\u017cczyk","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology and General Pediatrics, Medical University of Warsaw, Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rados\u0142aw","family":"Pietrzak","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology and General Pediatrics, Medical University of Warsaw, Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariusz","family":"Furmanek","sequence":"additional","affiliation":[{"name":"Department of Pediatric Radiology, Medical University of Warsaw, Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariusz","family":"Ku\u015bmierczyk","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery and Transplantology, Medical University of Warsaw, Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo\u017cena","family":"Werner","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology and General Pediatrics, Medical University of Warsaw, Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,7,31]]},"reference":[{"key":"R1-20260731","doi-asserted-by":"crossref","first-page":"7559","DOI":"10.3390\/ijms21207559","article-title":"Gorlin syndrome: Recent advances in genetic testing and molecular and cellular biological research","volume":"21","author":"Onodera","year":"2020","journal-title":"Int J Mol Sci"},{"key":"R2-20260731","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1111\/bjd.20700","article-title":"A guideline for the clinical management of basal cell naevus syndrome (Gorlin-Goltz syndrome)","volume":"186","author":"Verkouteren","year":"2022","journal-title":"Br J Dermatol"},{"key":"R3-20260731","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1186\/s13023-023-02792-5","article-title":"Siblings with Gorlin-Goltz syndrome associated with cardiac tumors: A case report and 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