{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:03:03Z","timestamp":1787169783438,"version":"build-2736575974"},"reference-count":3,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The impact of a dilated left ventricular (LV) on right ventricular (RV) diastolic function has not been investigated. We hypothesized that in patients with a patent ductus arteriosus (PDA), LV dilation causes elevation of the RV end-diastolic pressure (RVEDP) through ventricular-ventricular interaction. We identified patients\u2019 ages 6 months to 18 years who underwent transcatheter PDA closure at our center from 2010 to 2019. One hundred and thirteen patients were included with a median age of 3 years (0.5\u201318). The median LV end-diastolic dimension (LVEDD) Z-score was 1.6 (\u22121.4\u20136.3). RVEDP was positively associated with RV systolic pressure (0.38,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; 0.01), ratio of pulmonary artery\/aortic systolic pressure (0.4,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; 0.01), and pulmonary capillary wedge pressure (0.71,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; 0.01). RVEDP was not associated with LVEDD Z-score (0.03,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = 0.74). In children with a PDA, RVEDP was not associated with LV dilation, but was positively associated with RV systolic pressure.\n                  <\/jats:p>","DOI":"10.4103\/apc.apc_84_22","type":"journal-article","created":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T07:21:54Z","timestamp":1680506514000},"page":"41-44","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["The relationship between left ventricular dilation and right ventricular diastolic function in children with a patent ductus arteriosus"],"prefix":"10.4103","volume":"16","author":[{"given":"Cole","family":"Miller","sequence":"first","affiliation":[{"name":"Division of Pediatric Cardiology, Children\u2019s Hospital of Atlanta, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Anderson","sequence":"additional","affiliation":[{"name":"Center for Outcomes Research and Evaluation, Atrium Health, Charlotte, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph A.","family":"Paolillo","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology, Levine Children\u2019s Hospital, Charlotte, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew C.","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology, Levine Children\u2019s Hospital, Charlotte, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,4,4]]},"reference":[{"key":"R1-20240901","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.amjcard.2011.09.028","article-title":"Relation of left ventricular end diastolic pressure to right ventricular end diastolic volume after operative treatment of tetralogy of Fallot","volume":"109","author":"Schwartz","year":"2012","journal-title":"Am J Cardiol"},{"key":"R2-20240901","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1161\/CIRCULATIONAHA.113.001375","article-title":"Right versus left ventricular failure:Differences, similarities, and interactions","volume":"129","author":"Friedberg","year":"2014","journal-title":"Circulation"},{"key":"R3-20240901","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1164\/ajrccm.150.3.8087359","article-title":"Pathophysiology of cor pulmonale in chronic obstructive pulmonary disease","volume":"150","author":"MacNee","year":"1994","journal-title":"Part One. Am J Respir Crit Care Med"}],"container-title":["Annals of Pediatric Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/apc.apc_84_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:12:58Z","timestamp":1787166778000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/apc.apc_84_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":3,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/apc.apc_84_22","relation":{},"ISSN":["0974-2069","0974-5149"],"issn-type":[{"value":"0974-2069","type":"print"},{"value":"0974-5149","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"2022-07-16","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-06","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}