{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:05:53Z","timestamp":1787169953367,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Pheochromocytomas are catecholamine-producing tumors derived from the adrenomedullary chromaffin cells. The presentation is a classic triad of episodic headaches, sweating, and tachycardia. Hypertensive crisis can occur due to profuse catecholamine excess. Unusual manifestations mimicking cardiogenic shock, arrhythmia, and myocarditis have been rarely reported in children. We present a case with uncommon manifestations of pheochromocytoma in a child, including the episodes of exercised-induced presyncope with QT prolongation, and subsequently cardiogenic shock due to fulminant myocarditis. He later developed hypertensive crisis. The adrenal mass on abdominal computed tomography with an increased chromogranin A level and elevated plasma normetanephrine, and the histological study confirmed the diagnosis of pheochromocytoma. Cardiac functions completely recovered after adrenalectomy. Genetic testing was positive for von Hippel-Lindau syndrome. We describe pheochromocytoma crisis presenting with prolonged QT and catecholamine-induced myocarditis. We discuss the clues to assist in the diagnosis of this condition and its appropriate treatment.<\/jats:p>","DOI":"10.4103\/apc.apc_87_22","type":"journal-article","created":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T01:00:15Z","timestamp":1692234015000},"page":"144-146","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Pheochromocytoma presenting with QT prolongation and catecholamine-induced myocarditis in a child"],"prefix":"10.4103","volume":"16","author":[{"given":"Kwannapas","family":"Saengsin","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saviga","family":"Sethasathien","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prapai","family":"Dejkhamron","sequence":"additional","affiliation":[{"name":"Division of Endocrine and Metabolism, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rekwan","family":"Sittiwangkul","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krit","family":"Makonkawkeyoon","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suchaya","family":"Silvilairat","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karn","family":"Wejaphikul","sequence":"additional","affiliation":[{"name":"Division of Endocrine and Metabolism, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yupada","family":"Pongprot","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,8,16]]},"reference":[{"key":"R1-20240901","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1161\/CIRCHEARTFAILURE.115.002036","article-title":"Heart failure due to adrenergic myocardial toxicity from a pheochromocytoma","volume":"8","author":"De 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pheochromocytoma","volume":"13","author":"Roghi","year":"2011","journal-title":"J Cardiovasc Magn Reson"},{"key":"R6-20240901","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1016\/j.surg.2011.09.001","article-title":"Cardiovascular dysfunction and catecholamine cardiomyopathy in pheochromocytoma patients and their reversal following surgical cure:Results of a prospective case-control study","volume":"150","author":"Agarwal","year":"2011","journal-title":"Surgery"},{"key":"R7-20240901","doi-asserted-by":"crossref","first-page":"1545.e3","DOI":"10.1016\/j.ajem.2015.07.025","article-title":"A peculiar etiology of acute heart failure:Adrenergic myocarditis","volume":"33","author":"Polito","year":"2015","journal-title":"Am J Emerg Med"},{"key":"R8-20240901","first-page":"346","article-title":"Acute myocarditis secondary to pheochromocytoma","volume":"83","author":"Magalh\u00e3es","year":"2004","journal-title":"Arq Bras 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